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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
STAC2
Full Name:
SH3 and cysteine-rich domain-containing protein 2
Alias:
SH3 and cysteine-rich domain-containing protein 2: SRC homology 3 and cysteine-rich domain protein 2: 24b2/STAC2
Type:
Mass (Da):
44990
Number AA:
411
UniProt ID:
Q6ZMT1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0007242
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T16
N
E
P
D
D
A
A
T
H
S
P
P
G
T
V
Site 2
S18
P
D
D
A
A
T
H
S
P
P
G
T
V
S
A
Site 3
T22
A
T
H
S
P
P
G
T
V
S
A
L
Q
E
T
Site 4
S37
K
L
Q
R
F
K
R
S
L
S
L
K
T
I
L
Site 5
S39
Q
R
F
K
R
S
L
S
L
K
T
I
L
R
S
Site 6
T42
K
R
S
L
S
L
K
T
I
L
R
S
K
S
L
Site 7
S46
S
L
K
T
I
L
R
S
K
S
L
E
N
F
F
Site 8
S48
K
T
I
L
R
S
K
S
L
E
N
F
F
L
R
Site 9
S58
N
F
F
L
R
S
G
S
E
L
K
C
P
T
E
Site 10
T72
E
V
L
L
T
P
P
T
P
L
P
P
P
S
P
Site 11
S78
P
T
P
L
P
P
P
S
P
P
P
T
A
S
D
Site 12
T82
P
P
P
S
P
P
P
T
A
S
D
R
G
L
A
Site 13
S84
P
S
P
P
P
T
A
S
D
R
G
L
A
T
P
Site 14
T90
A
S
D
R
G
L
A
T
P
S
P
S
P
C
P
Site 15
S92
D
R
G
L
A
T
P
S
P
S
P
C
P
V
P
Site 16
S94
G
L
A
T
P
S
P
S
P
C
P
V
P
R
P
Site 17
S112
L
K
P
V
R
L
H
S
F
Q
E
H
V
F
K
Site 18
S122
E
H
V
F
K
R
A
S
P
C
E
L
C
H
Q
Site 19
S135
H
Q
L
I
V
G
N
S
K
Q
G
L
R
C
K
Site 20
S168
C
P
G
K
T
S
T
S
F
R
R
N
F
S
S
Site 21
S174
T
S
F
R
R
N
F
S
S
P
L
L
V
H
E
Site 22
S175
S
F
R
R
N
F
S
S
P
L
L
V
H
E
P
Site 23
T188
E
P
P
P
V
C
A
T
S
K
E
S
P
P
T
Site 24
S189
P
P
P
V
C
A
T
S
K
E
S
P
P
T
G
Site 25
S192
V
C
A
T
S
K
E
S
P
P
T
G
D
S
G
Site 26
T195
T
S
K
E
S
P
P
T
G
D
S
G
K
V
D
Site 27
S198
E
S
P
P
T
G
D
S
G
K
V
D
P
V
Y
Site 28
Y205
S
G
K
V
D
P
V
Y
E
T
L
R
Y
G
T
Site 29
T207
K
V
D
P
V
Y
E
T
L
R
Y
G
T
S
L
Site 30
T212
Y
E
T
L
R
Y
G
T
S
L
A
L
M
N
R
Site 31
S213
E
T
L
R
Y
G
T
S
L
A
L
M
N
R
S
Site 32
S220
S
L
A
L
M
N
R
S
S
F
S
S
T
S
E
Site 33
S221
L
A
L
M
N
R
S
S
F
S
S
T
S
E
S
Site 34
S223
L
M
N
R
S
S
F
S
S
T
S
E
S
P
T
Site 35
S224
M
N
R
S
S
F
S
S
T
S
E
S
P
T
R
Site 36
T225
N
R
S
S
F
S
S
T
S
E
S
P
T
R
S
Site 37
S226
R
S
S
F
S
S
T
S
E
S
P
T
R
S
L
Site 38
S228
S
F
S
S
T
S
E
S
P
T
R
S
L
S
E
Site 39
T230
S
S
T
S
E
S
P
T
R
S
L
S
E
R
D
Site 40
S232
T
S
E
S
P
T
R
S
L
S
E
R
D
E
L
Site 41
S234
E
S
P
T
R
S
L
S
E
R
D
E
L
T
E
Site 42
T240
L
S
E
R
D
E
L
T
E
D
G
E
G
S
I
Site 43
S246
L
T
E
D
G
E
G
S
I
R
S
S
E
E
G
Site 44
S249
D
G
E
G
S
I
R
S
S
E
E
G
P
G
D
Site 45
S250
G
E
G
S
I
R
S
S
E
E
G
P
G
D
S
Site 46
S257
S
E
E
G
P
G
D
S
A
S
P
V
F
T
A
Site 47
S259
E
G
P
G
D
S
A
S
P
V
F
T
A
P
A
Site 48
T263
D
S
A
S
P
V
F
T
A
P
A
E
S
E
G
Site 49
S277
G
P
G
P
E
E
K
S
P
G
Q
Q
L
P
K
Site 50
Y295
R
K
D
V
G
P
M
Y
S
Y
V
A
L
Y
K
Site 51
Y370
S
G
N
K
E
Q
G
Y
M
S
L
K
E
N
Q
Site 52
S395
A
D
G
F
I
R
V
S
S
G
K
K
R
G
L
Site 53
S396
D
G
F
I
R
V
S
S
G
K
K
R
G
L
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation