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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SPOCD1
Full Name:
SPOC domain-containing protein 1
Alias:
Type:
Mass (Da):
130027
Number AA:
1216
UniProt ID:
Q6ZMY3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
A
G
D
V
E
G
P
S
T
G
D
P
V
L
S
Site 2
T12
G
D
V
E
G
P
S
T
G
D
P
V
L
S
P
Site 3
S18
S
T
G
D
P
V
L
S
P
Q
H
N
C
E
L
Site 4
S33
L
Q
N
M
E
G
A
S
S
M
P
G
L
S
P
Site 5
S34
Q
N
M
E
G
A
S
S
M
P
G
L
S
P
D
Site 6
S39
A
S
S
M
P
G
L
S
P
D
G
P
G
A
S
Site 7
S46
S
P
D
G
P
G
A
S
S
G
P
G
V
R
A
Site 8
S47
P
D
G
P
G
A
S
S
G
P
G
V
R
A
G
Site 9
S55
G
P
G
V
R
A
G
S
R
R
K
I
P
R
K
Site 10
S69
K
E
A
L
R
G
G
S
S
R
A
A
G
A
A
Site 11
S106
G
L
H
M
Q
L
P
S
V
P
T
Q
G
R
A
Site 12
T115
P
T
Q
G
R
A
L
T
S
K
R
L
Q
V
S
Site 13
S116
T
Q
G
R
A
L
T
S
K
R
L
Q
V
S
L
Site 14
S122
T
S
K
R
L
Q
V
S
L
C
D
I
L
D
D
Site 15
S130
L
C
D
I
L
D
D
S
C
P
R
K
L
C
S
Site 16
S137
S
C
P
R
K
L
C
S
R
S
A
G
L
P
E
Site 17
S173
E
A
R
D
G
G
M
S
S
P
G
C
D
R
R
Site 18
S174
A
R
D
G
G
M
S
S
P
G
C
D
R
R
S
Site 19
S181
S
P
G
C
D
R
R
S
P
T
L
S
K
E
E
Site 20
T183
G
C
D
R
R
S
P
T
L
S
K
E
E
P
P
Site 21
S185
D
R
R
S
P
T
L
S
K
E
E
P
P
G
R
Site 22
T195
E
P
P
G
R
P
L
T
S
S
P
D
P
V
P
Site 23
S196
P
P
G
R
P
L
T
S
S
P
D
P
V
P
V
Site 24
S197
P
G
R
P
L
T
S
S
P
D
P
V
P
V
R
Site 25
S216
W
R
R
Q
G
A
H
S
E
C
E
E
G
A
G
Site 26
S231
D
F
L
W
L
D
Q
S
P
R
G
D
N
L
L
Site 27
S239
P
R
G
D
N
L
L
S
V
G
D
P
P
Q
V
Site 28
S260
G
G
P
C
R
P
P
S
P
K
D
T
G
S
G
Site 29
T264
R
P
P
S
P
K
D
T
G
S
G
P
G
E
P
Site 30
S266
P
S
P
K
D
T
G
S
G
P
G
E
P
G
G
Site 31
S274
G
P
G
E
P
G
G
S
G
A
G
C
A
S
G
Site 32
S280
G
S
G
A
G
C
A
S
G
T
E
K
F
G
Y
Site 33
Y287
S
G
T
E
K
F
G
Y
L
P
A
T
G
D
G
Site 34
T291
K
F
G
Y
L
P
A
T
G
D
G
P
Q
P
G
Site 35
S299
G
D
G
P
Q
P
G
S
P
C
G
P
V
G
F
Site 36
S310
P
V
G
F
P
V
P
S
G
G
E
S
L
S
S
Site 37
S314
P
V
P
S
G
G
E
S
L
S
S
A
A
Q
A
Site 38
S316
P
S
G
G
E
S
L
S
S
A
A
Q
A
P
P
Site 39
S317
S
G
G
E
S
L
S
S
A
A
Q
A
P
P
Q
Site 40
S337
L
G
A
S
A
Q
A
S
A
E
Q
Q
E
A
V
Site 41
S351
V
C
V
V
R
T
G
S
D
E
G
Q
A
P
A
Site 42
S372
E
A
K
A
Q
P
A
S
R
G
R
L
E
Q
G
Site 43
T386
G
L
A
A
P
A
D
T
C
A
S
S
R
E
P
Site 44
S389
A
P
A
D
T
C
A
S
S
R
E
P
L
G
G
Site 45
S390
P
A
D
T
C
A
S
S
R
E
P
L
G
G
L
Site 46
S398
R
E
P
L
G
G
L
S
S
S
L
D
T
E
A
Site 47
S399
E
P
L
G
G
L
S
S
S
L
D
T
E
A
S
Site 48
S400
P
L
G
G
L
S
S
S
L
D
T
E
A
S
R
Site 49
T403
G
L
S
S
S
L
D
T
E
A
S
R
A
C
S
Site 50
S406
S
S
L
D
T
E
A
S
R
A
C
S
G
P
F
Site 51
S410
T
E
A
S
R
A
C
S
G
P
F
M
E
Q
R
Site 52
S419
P
F
M
E
Q
R
R
S
K
G
T
K
N
L
K
Site 53
T438
P
C
A
Q
D
R
G
T
D
R
S
S
D
N
S
Site 54
S441
Q
D
R
G
T
D
R
S
S
D
N
S
H
Q
D
Site 55
S442
D
R
G
T
D
R
S
S
D
N
S
H
Q
D
R
Site 56
S445
T
D
R
S
S
D
N
S
H
Q
D
R
P
E
E
Site 57
S454
Q
D
R
P
E
E
P
S
P
G
G
C
P
R
L
Site 58
S512
E
D
L
M
E
V
S
S
P
S
P
A
Q
R
L
Site 59
S514
L
M
E
V
S
S
P
S
P
A
Q
R
L
R
R
Site 60
S539
G
C
Q
V
F
Q
P
S
P
S
G
G
T
A
G
Site 61
S552
A
G
D
P
G
G
L
S
D
P
F
Y
P
P
R
Site 62
Y556
G
G
L
S
D
P
F
Y
P
P
R
S
G
S
L
Site 63
S560
D
P
F
Y
P
P
R
S
G
S
L
A
L
G
D
Site 64
S562
F
Y
P
P
R
S
G
S
L
A
L
G
D
P
S
Site 65
S569
S
L
A
L
G
D
P
S
S
D
P
A
C
S
Q
Site 66
S570
L
A
L
G
D
P
S
S
D
P
A
C
S
Q
S
Site 67
S575
P
S
S
D
P
A
C
S
Q
S
G
P
M
E
A
Site 68
S577
S
D
P
A
C
S
Q
S
G
P
M
E
A
E
E
Site 69
S586
P
M
E
A
E
E
D
S
L
P
E
Q
P
E
D
Site 70
S603
Q
L
Q
Q
E
K
P
S
L
Y
I
G
V
R
G
Site 71
Y605
Q
Q
E
K
P
S
L
Y
I
G
V
R
G
T
V
Site 72
T622
S
M
Q
E
V
L
W
T
R
L
R
E
L
P
D
Site 73
T652
E
A
A
L
W
D
L
T
Q
G
T
N
G
R
Y
Site 74
T661
G
T
N
G
R
Y
K
T
K
Y
R
S
L
L
F
Site 75
Y663
N
G
R
Y
K
T
K
Y
R
S
L
L
F
N
L
Site 76
T688
K
V
V
H
G
D
V
T
P
Y
D
L
V
R
M
Site 77
Y690
V
H
G
D
V
T
P
Y
D
L
V
R
M
S
S
Site 78
S696
P
Y
D
L
V
R
M
S
S
M
Q
L
A
P
Q
Site 79
S697
Y
D
L
V
R
M
S
S
M
Q
L
A
P
Q
E
Site 80
S733
E
P
C
R
L
P
A
S
K
M
T
H
K
G
E
Site 81
T750
I
Q
R
D
M
D
Q
T
L
T
L
E
D
L
V
Site 82
T752
R
D
M
D
Q
T
L
T
L
E
D
L
V
G
P
Site 83
S774
P
Q
A
L
P
I
A
S
E
D
T
T
G
Q
H
Site 84
T778
P
I
A
S
E
D
T
T
G
Q
H
D
H
H
F
Site 85
S805
P
S
N
E
L
L
G
S
F
E
A
A
K
S
C
Site 86
S811
G
S
F
E
A
A
K
S
C
G
D
N
I
F
Q
Site 87
S822
N
I
F
Q
K
A
L
S
Q
T
P
M
P
A
P
Site 88
T824
F
Q
K
A
L
S
Q
T
P
M
P
A
P
E
M
Site 89
T834
P
A
P
E
M
P
K
T
R
E
L
S
P
T
E
Site 90
S838
M
P
K
T
R
E
L
S
P
T
E
P
Q
D
R
Site 91
T840
K
T
R
E
L
S
P
T
E
P
Q
D
R
V
P
Site 92
S849
P
Q
D
R
V
P
P
S
G
L
H
V
P
A
A
Site 93
S875
E
G
V
L
D
M
F
S
I
K
R
F
R
A
R
Site 94
S887
R
A
R
A
Q
L
V
S
G
H
S
C
R
L
V
Site 95
T940
C
P
H
G
A
R
D
T
Q
N
C
R
L
L
Y
Site 96
Y947
T
Q
N
C
R
L
L
Y
S
Y
L
N
D
R
Q
Site 97
Y949
N
C
R
L
L
Y
S
Y
L
N
D
R
Q
R
H
Site 98
S960
R
Q
R
H
G
L
A
S
V
E
H
M
G
M
V
Site 99
T1023
P
K
E
G
L
P
D
T
A
G
S
S
P
W
L
Site 100
S1026
G
L
P
D
T
A
G
S
S
P
W
L
G
K
V
Site 101
S1027
L
P
D
T
A
G
S
S
P
W
L
G
K
V
Q
Site 102
S1038
G
K
V
Q
K
M
V
S
F
N
S
K
V
E
K
Site 103
Y1047
N
S
K
V
E
K
R
Y
Y
Q
P
D
D
R
R
Site 104
Y1048
S
K
V
E
K
R
Y
Y
Q
P
D
D
R
R
P
Site 105
T1062
P
N
V
P
L
K
G
T
P
P
P
G
G
A
W
Site 106
S1072
P
G
G
A
W
Q
Q
S
Q
G
R
G
S
I
A
Site 107
S1077
Q
Q
S
Q
G
R
G
S
I
A
P
R
G
I
S
Site 108
S1084
S
I
A
P
R
G
I
S
A
W
Q
R
P
P
R
Site 109
S1120
P
E
P
G
L
R
Q
S
Q
H
P
Y
S
V
A
Site 110
Y1124
L
R
Q
S
Q
H
P
Y
S
V
A
P
A
G
H
Site 111
S1125
R
Q
S
Q
H
P
Y
S
V
A
P
A
G
H
G
Site 112
S1155
A
L
L
R
H
L
E
S
L
A
T
M
S
H
Q
Site 113
T1158
R
H
L
E
S
L
A
T
M
S
H
Q
L
Q
A
Site 114
T1171
Q
A
L
L
C
P
Q
T
K
S
S
I
P
R
P
Site 115
S1173
L
L
C
P
Q
T
K
S
S
I
P
R
P
L
Q
Site 116
S1174
L
C
P
Q
T
K
S
S
I
P
R
P
L
Q
R
Site 117
S1183
P
R
P
L
Q
R
L
S
S
A
L
A
A
P
E
Site 118
S1184
R
P
L
Q
R
L
S
S
A
L
A
A
P
E
P
Site 119
S1198
P
P
G
P
A
R
D
S
S
L
G
P
T
D
E
Site 120
S1199
P
G
P
A
R
D
S
S
L
G
P
T
D
E
A
Site 121
T1203
R
D
S
S
L
G
P
T
D
E
A
G
S
E
C
Site 122
S1208
G
P
T
D
E
A
G
S
E
C
P
F
P
R
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation