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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RNF19B
Full Name:
E3 ubiquitin-protein ligase RNF19B
Alias:
IBR domain-containing protein 3;Natural killer lytic-associated molecule;RING finger protein 19B
Type:
Mass (Da):
77925
Number AA:
732
UniProt ID:
Q6ZMZ0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
G
S
E
K
D
S
E
S
P
R
S
T
S
Site 2
S9
G
S
E
K
D
S
E
S
P
R
S
T
S
L
H
Site 3
S12
K
D
S
E
S
P
R
S
T
S
L
H
A
A
A
Site 4
T13
D
S
E
S
P
R
S
T
S
L
H
A
A
A
P
Site 5
S14
S
E
S
P
R
S
T
S
L
H
A
A
A
P
D
Site 6
S26
A
P
D
P
K
C
R
S
G
G
R
R
R
R
L
Site 7
T34
G
G
R
R
R
R
L
T
L
H
S
V
F
S
A
Site 8
S37
R
R
R
L
T
L
H
S
V
F
S
A
S
A
R
Site 9
S40
L
T
L
H
S
V
F
S
A
S
A
R
G
R
R
Site 10
S42
L
H
S
V
F
S
A
S
A
R
G
R
R
A
R
Site 11
S136
E
R
A
P
R
L
L
S
C
P
H
R
S
C
R
Site 12
Y149
C
R
D
C
L
R
H
Y
L
R
L
E
I
S
E
Site 13
S155
H
Y
L
R
L
E
I
S
E
S
R
V
P
I
S
Site 14
S157
L
R
L
E
I
S
E
S
R
V
P
I
S
C
P
Site 15
S162
S
E
S
R
V
P
I
S
C
P
E
C
S
E
R
Site 16
S167
P
I
S
C
P
E
C
S
E
R
L
N
P
H
D
Site 17
Y188
D
P
P
L
M
H
K
Y
E
E
F
M
L
R
R
Site 18
Y196
E
E
F
M
L
R
R
Y
L
A
S
D
P
D
C
Site 19
T261
A
R
Q
Q
R
A
Q
T
L
R
V
R
T
K
H
Site 20
T266
A
Q
T
L
R
V
R
T
K
H
T
S
G
L
S
Site 21
S270
R
V
R
T
K
H
T
S
G
L
S
Y
G
Q
E
Site 22
S273
T
K
H
T
S
G
L
S
Y
G
Q
E
S
G
P
Site 23
Y274
K
H
T
S
G
L
S
Y
G
Q
E
S
G
P
A
Site 24
Y293
P
C
P
R
C
S
A
Y
I
I
K
M
N
D
G
Site 25
Y327
K
E
I
S
D
L
H
Y
L
S
P
S
G
C
T
Site 26
Y388
G
R
K
I
H
S
R
Y
E
G
R
K
T
S
K
Site 27
T393
S
R
Y
E
G
R
K
T
S
K
H
K
R
N
L
Site 28
S394
R
Y
E
G
R
K
T
S
K
H
K
R
N
L
A
Site 29
S449
R
G
G
G
C
G
V
S
T
A
N
G
K
G
V
Site 30
T450
G
G
G
C
G
V
S
T
A
N
G
K
G
V
K
Site 31
T468
D
E
D
D
G
P
I
T
V
A
D
A
W
R
A
Site 32
S480
W
R
A
L
K
N
P
S
I
G
E
S
S
I
E
Site 33
S484
K
N
P
S
I
G
E
S
S
I
E
G
L
T
S
Site 34
S485
N
P
S
I
G
E
S
S
I
E
G
L
T
S
V
Site 35
T490
E
S
S
I
E
G
L
T
S
V
L
S
T
S
G
Site 36
S494
E
G
L
T
S
V
L
S
T
S
G
S
P
T
D
Site 37
T495
G
L
T
S
V
L
S
T
S
G
S
P
T
D
G
Site 38
T500
L
S
T
S
G
S
P
T
D
G
L
S
V
M
Q
Site 39
S504
G
S
P
T
D
G
L
S
V
M
Q
G
P
Y
S
Site 40
S511
S
V
M
Q
G
P
Y
S
E
T
A
S
F
A
A
Site 41
S515
G
P
Y
S
E
T
A
S
F
A
A
L
S
G
G
Site 42
S530
T
L
S
G
G
I
L
S
S
G
K
G
K
Y
S
Site 43
S531
L
S
G
G
I
L
S
S
G
K
G
K
Y
S
R
Site 44
Y536
L
S
S
G
K
G
K
Y
S
R
L
E
V
Q
A
Site 45
S537
S
S
G
K
G
K
Y
S
R
L
E
V
Q
A
D
Site 46
S556
I
F
P
K
D
T
A
S
L
G
A
I
S
D
N
Site 47
S561
T
A
S
L
G
A
I
S
D
N
A
S
T
R
A
Site 48
S565
G
A
I
S
D
N
A
S
T
R
A
M
A
G
S
Site 49
S572
S
T
R
A
M
A
G
S
I
I
S
S
Y
N
P
Site 50
S576
M
A
G
S
I
I
S
S
Y
N
P
Q
D
R
E
Site 51
Y577
A
G
S
I
I
S
S
Y
N
P
Q
D
R
E
C
Site 52
S598
V
D
I
E
A
K
P
S
H
Y
Q
L
V
S
G
Site 53
Y600
I
E
A
K
P
S
H
Y
Q
L
V
S
G
S
S
Site 54
S604
P
S
H
Y
Q
L
V
S
G
S
S
T
E
D
S
Site 55
S606
H
Y
Q
L
V
S
G
S
S
T
E
D
S
L
H
Site 56
S607
Y
Q
L
V
S
G
S
S
T
E
D
S
L
H
V
Site 57
T608
Q
L
V
S
G
S
S
T
E
D
S
L
H
V
H
Site 58
S611
S
G
S
S
T
E
D
S
L
H
V
H
A
Q
M
Site 59
S626
A
E
N
E
E
E
G
S
G
G
G
G
S
E
E
Site 60
S631
E
G
S
G
G
G
G
S
E
E
D
P
P
C
R
Site 61
S656
A
S
K
P
W
D
I
S
L
A
Q
P
E
S
I
Site 62
S662
I
S
L
A
Q
P
E
S
I
R
S
D
L
E
S
Site 63
S665
A
Q
P
E
S
I
R
S
D
L
E
S
S
D
A
Site 64
S669
S
I
R
S
D
L
E
S
S
D
A
Q
S
D
D
Site 65
S670
I
R
S
D
L
E
S
S
D
A
Q
S
D
D
V
Site 66
S674
L
E
S
S
D
A
Q
S
D
D
V
P
D
I
T
Site 67
T681
S
D
D
V
P
D
I
T
S
D
E
C
G
S
P
Site 68
S682
D
D
V
P
D
I
T
S
D
E
C
G
S
P
R
Site 69
S687
I
T
S
D
E
C
G
S
P
R
S
H
T
A
A
Site 70
S690
D
E
C
G
S
P
R
S
H
T
A
A
C
P
S
Site 71
T692
C
G
S
P
R
S
H
T
A
A
C
P
S
T
P
Site 72
S697
S
H
T
A
A
C
P
S
T
P
R
A
Q
G
A
Site 73
T698
H
T
A
A
C
P
S
T
P
R
A
Q
G
A
P
Site 74
S706
P
R
A
Q
G
A
P
S
P
S
A
H
M
N
L
Site 75
S708
A
Q
G
A
P
S
P
S
A
H
M
N
L
S
A
Site 76
S714
P
S
A
H
M
N
L
S
A
L
A
E
G
Q
T
Site 77
T721
S
A
L
A
E
G
Q
T
V
L
K
P
E
G
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation