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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LRRC9
Full Name:
Leucine-rich repeat-containing protein 9
Alias:
FLJ46156
Type:
Uncharacterized
Mass (Da):
128135
Number AA:
1111
UniProt ID:
Q6ZRR7
International Prot ID:
IPI00394879
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S32
E
M
V
G
Q
E
G
S
D
T
S
K
L
E
M
Site 2
T34
V
G
Q
E
G
S
D
T
S
K
L
E
M
F
F
Site 3
S35
G
Q
E
G
S
D
T
S
K
L
E
M
F
F
L
Site 4
Y104
C
R
N
L
E
K
L
Y
L
Y
F
N
K
I
S
Site 5
Y106
N
L
E
K
L
Y
L
Y
F
N
K
I
S
K
I
Site 6
T140
K
N
I
E
G
L
Q
T
L
K
N
L
K
D
L
Site 7
S163
S
I
G
R
C
L
D
S
N
E
Q
L
E
R
L
Site 8
S173
Q
L
E
R
L
N
L
S
G
N
Q
I
C
S
F
Site 9
S179
L
S
G
N
Q
I
C
S
F
K
E
L
T
N
L
Site 10
T187
F
K
E
L
T
N
L
T
R
L
P
C
L
K
D
Site 11
Y219
N
Y
S
T
H
V
L
Y
H
L
P
C
L
Q
R
Site 12
T229
P
C
L
Q
R
F
D
T
L
D
V
S
A
K
Q
Site 13
S233
R
F
D
T
L
D
V
S
A
K
Q
I
K
E
L
Site 14
T243
Q
I
K
E
L
A
D
T
T
A
M
K
K
I
M
Site 15
Y251
T
A
M
K
K
I
M
Y
Y
N
M
R
I
K
T
Site 16
Y252
A
M
K
K
I
M
Y
Y
N
M
R
I
K
T
L
Site 17
T258
Y
Y
N
M
R
I
K
T
L
Q
R
H
L
K
E
Site 18
S289
E
E
R
V
K
L
F
S
F
V
K
K
T
L
E
Site 19
T294
L
F
S
F
V
K
K
T
L
E
R
E
L
A
E
Site 20
S305
E
L
A
E
L
K
G
S
G
K
G
H
S
D
G
Site 21
S310
K
G
S
G
K
G
H
S
D
G
S
N
N
S
K
Site 22
S313
G
K
G
H
S
D
G
S
N
N
S
K
V
T
D
Site 23
T323
S
K
V
T
D
P
E
T
L
K
S
C
E
T
V
Site 24
S326
T
D
P
E
T
L
K
S
C
E
T
V
T
E
E
Site 25
T329
E
T
L
K
S
C
E
T
V
T
E
E
P
S
L
Site 26
T331
L
K
S
C
E
T
V
T
E
E
P
S
L
Q
Q
Site 27
T352
N
A
L
N
E
R
V
T
F
W
N
K
K
L
D
Site 28
T427
D
F
R
T
Y
G
I
T
G
V
K
V
K
R
I
Site 29
S462
E
N
E
D
M
H
D
S
E
S
Y
R
R
M
L
Site 30
Y465
D
M
H
D
S
E
S
Y
R
R
M
L
E
C
L
Site 31
S498
L
E
K
G
F
K
D
S
E
T
S
K
L
P
L
Site 32
T500
K
G
F
K
D
S
E
T
S
K
L
P
L
K
K
Site 33
S513
K
K
E
A
I
I
V
S
N
S
L
S
I
S
E
Site 34
S519
V
S
N
S
L
S
I
S
E
C
P
R
I
E
F
Site 35
S538
H
K
D
E
K
K
I
S
L
K
H
E
L
F
R
Site 36
S567
V
Q
A
H
E
K
E
S
I
S
Q
S
N
Y
P
Site 37
S569
A
H
E
K
E
S
I
S
Q
S
N
Y
P
M
V
Site 38
S571
E
K
E
S
I
S
Q
S
N
Y
P
M
V
N
S
Site 39
Y573
E
S
I
S
Q
S
N
Y
P
M
V
N
S
V
F
Site 40
S589
P
R
K
Y
L
L
N
S
V
M
G
Q
R
N
C
Site 41
S651
S
K
K
N
P
E
V
S
V
F
S
K
D
L
K
Site 42
S654
N
P
E
V
S
V
F
S
K
D
L
K
F
D
D
Site 43
S678
K
A
R
P
K
L
I
S
L
D
D
K
T
I
L
Site 44
S698
S
V
Y
S
H
I
V
S
L
N
L
H
G
N
S
Site 45
S705
S
L
N
L
H
G
N
S
L
S
K
L
R
D
L
Site 46
S707
N
L
H
G
N
S
L
S
K
L
R
D
L
S
K
Site 47
S713
L
S
K
L
R
D
L
S
K
L
T
G
L
R
K
Site 48
Y735
F
T
C
L
D
D
V
Y
H
L
Y
N
L
E
Y
Site 49
Y738
L
D
D
V
Y
H
L
Y
N
L
E
Y
L
D
A
Site 50
Y742
Y
H
L
Y
N
L
E
Y
L
D
A
S
H
N
H
Site 51
T752
A
S
H
N
H
V
I
T
L
E
G
F
R
G
L
Site 52
S768
K
L
K
H
L
D
L
S
W
N
Q
L
K
K
S
Site 53
T804
N
P
W
Q
K
P
A
T
L
R
L
S
V
I
G
Site 54
S808
K
P
A
T
L
R
L
S
V
I
G
R
L
K
T
Site 55
S845
G
T
R
I
T
Q
L
S
L
L
R
H
S
S
T
Site 56
S850
Q
L
S
L
L
R
H
S
S
T
K
E
E
R
P
Site 57
S851
L
S
L
L
R
H
S
S
T
K
E
E
R
P
R
Site 58
T852
S
L
L
R
H
S
S
T
K
E
E
R
P
R
I
Site 59
S861
E
E
R
P
R
I
L
S
I
W
P
S
A
K
I
Site 60
T870
W
P
S
A
K
I
L
T
Q
V
S
K
L
G
P
Site 61
S915
L
E
N
L
K
W
A
S
F
S
N
N
N
L
T
Site 62
T922
S
F
S
N
N
N
L
T
K
M
E
G
L
E
S
Site 63
S929
T
K
M
E
G
L
E
S
C
I
N
L
E
E
L
Site 64
S944
T
L
D
G
N
C
I
S
K
I
E
G
I
S
K
Site 65
S959
M
T
K
L
T
R
L
S
I
N
N
N
L
L
T
Site 66
T966
S
I
N
N
N
L
L
T
G
W
E
E
H
T
F
Site 67
S981
D
N
M
L
H
L
H
S
L
S
L
E
N
N
R
Site 68
S983
M
L
H
L
H
S
L
S
L
E
N
N
R
I
T
Site 69
T990
S
L
E
N
N
R
I
T
S
L
S
G
L
Q
K
Site 70
S991
L
E
N
N
R
I
T
S
L
S
G
L
Q
K
S
Site 71
S993
N
N
R
I
T
S
L
S
G
L
Q
K
S
F
T
Site 72
Y1010
E
L
Y
I
S
N
N
Y
I
A
V
N
Q
E
M
Site 73
S1065
D
G
I
P
I
E
P
S
E
T
D
S
A
K
D
Site 74
T1067
I
P
I
E
P
S
E
T
D
S
A
K
D
L
F
Site 75
S1069
I
E
P
S
E
T
D
S
A
K
D
L
F
G
G
Site 76
T1079
D
L
F
G
G
R
L
T
S
D
M
I
A
E
R
Site 77
S1080
L
F
G
G
R
L
T
S
D
M
I
A
E
R
Q
Site 78
T1101
Q
M
Q
E
L
N
W
T
S
S
S
I
R
T
V
Site 79
S1103
Q
E
L
N
W
T
S
S
S
I
R
T
V
D
L
Site 80
S1104
E
L
N
W
T
S
S
S
I
R
T
V
D
L
I
Site 81
T1130
N
L
Q
N
N
H
L
T
S
F
S
G
L
I
Y
Site 82
T1162
M
P
R
L
K
P
Q
T
H
L
T
S
R
Q
L
Site 83
T1165
L
K
P
Q
T
H
L
T
S
R
Q
L
L
Y
Q
Site 84
Y1171
L
T
S
R
Q
L
L
Y
Q
K
V
P
S
S
G
Site 85
S1177
L
Y
Q
K
V
P
S
S
G
Y
G
Q
Q
G
I
Site 86
T1187
G
Q
Q
G
I
S
K
T
N
R
D
I
M
S
S
Site 87
S1193
K
T
N
R
D
I
M
S
S
E
N
L
P
P
I
Site 88
S1194
T
N
R
D
I
M
S
S
E
N
L
P
P
I
M
Site 89
S1239
F
L
Q
G
N
E
I
S
Q
V
E
G
L
D
N
Site 90
S1262
V
D
H
N
R
I
R
S
F
N
D
S
A
F
A
Site 91
S1266
R
I
R
S
F
N
D
S
A
F
A
K
P
S
S
Site 92
S1292
R
E
L
G
K
L
Q
S
L
V
K
L
E
K
L
Site 93
Y1327
T
L
R
E
L
T
V
Y
G
N
P
I
C
R
K
Site 94
S1354
N
L
Q
M
L
D
G
S
P
V
N
S
D
D
R
Site 95
S1358
L
D
G
S
P
V
N
S
D
D
R
A
K
A
E
Site 96
S1377
E
L
Q
A
K
K
N
S
L
I
P
V
T
H
S
Site 97
T1382
K
N
S
L
I
P
V
T
H
S
P
M
D
G
R
Site 98
S1384
S
L
I
P
V
T
H
S
P
M
D
G
R
S
F
Site 99
S1390
H
S
P
M
D
G
R
S
F
G
Q
V
K
T
P
Site 100
T1396
R
S
F
G
Q
V
K
T
P
P
I
E
I
T
N
Site 101
S1416
G
F
S
H
Y
L
G
S
D
V
T
L
T
P
E
Site 102
T1419
H
Y
L
G
S
D
V
T
L
T
P
E
V
E
E
Site 103
T1447
C
L
K
R
N
E
H
T
P
R
N
S
P
V
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation