KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
DCDC5
Full Name:
Doublecortin domain-containing protein 5
Alias:
doublecortin domain containing 5; FLJ46154
Type:
Mass (Da):
72734
Number AA:
648
UniProt ID:
Q6ZRR9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0007242
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
K
K
P
I
C
K
T
T
E
P
Y
A
P
V
Site 2
S30
G
E
K
N
K
N
R
S
V
T
I
L
G
P
D
Site 3
T32
K
N
K
N
R
S
V
T
I
L
G
P
D
I
S
Site 4
S39
T
I
L
G
P
D
I
S
P
G
R
K
T
Q
C
Site 5
T44
D
I
S
P
G
R
K
T
Q
C
T
E
I
L
N
Site 6
T47
P
G
R
K
T
Q
C
T
E
I
L
N
L
P
S
Site 7
Y60
P
S
A
A
R
R
L
Y
N
E
K
G
K
E
I
Site 8
Y80
L
Q
R
D
E
L
V
Y
V
S
C
G
E
L
W
Site 9
S93
L
W
I
N
P
D
L
S
I
A
Q
Q
K
K
Q
Site 10
S135
E
V
Q
S
D
I
V
S
G
S
K
L
A
V
H
Site 11
T155
F
G
E
E
K
Q
V
T
E
P
E
E
K
Q
M
Site 12
T168
Q
M
Q
E
D
P
L
T
T
E
N
A
S
S
E
Site 13
S174
L
T
T
E
N
A
S
S
E
I
L
D
S
H
V
Site 14
S179
A
S
S
E
I
L
D
S
H
V
R
A
H
L
R
Site 15
S210
H
D
F
D
E
D
D
S
L
P
K
K
T
E
K
Site 16
S230
V
E
P
Q
K
K
H
S
C
S
P
K
H
S
K
Site 17
S232
P
Q
K
K
H
S
C
S
P
K
H
S
K
L
H
Site 18
S255
Y
R
D
G
Q
I
I
S
H
A
A
P
Q
L
V
Site 19
S283
V
V
L
V
E
K
K
S
D
G
S
H
Q
R
W
Site 20
T298
I
H
Q
E
D
S
R
T
F
H
L
V
S
N
P
Site 21
S312
P
D
L
V
L
A
V
S
M
T
K
T
R
N
E
Site 22
T316
L
A
V
S
M
T
K
T
R
N
E
V
C
G
Y
Site 23
Y323
T
R
N
E
V
C
G
Y
P
V
I
V
Q
K
Y
Site 24
Y387
E
N
I
D
Q
P
G
Y
C
Y
L
S
P
D
G
Site 25
Y389
I
D
Q
P
G
Y
C
Y
L
S
P
D
G
K
R
Site 26
S391
Q
P
G
Y
C
Y
L
S
P
D
G
K
R
K
T
Site 27
T398
S
P
D
G
K
R
K
T
M
L
C
L
A
C
G
Site 28
T431
L
C
I
S
G
T
K
T
Q
K
P
F
L
Q
G
Site 29
S451
S
V
A
E
V
D
L
S
C
D
K
A
E
K
T
Site 30
T458
S
C
D
K
A
E
K
T
L
S
Y
Y
Q
A
R
Site 31
S460
D
K
A
E
K
T
L
S
Y
Y
Q
A
R
L
L
Site 32
Y462
A
E
K
T
L
S
Y
Y
Q
A
R
L
L
S
L
Site 33
S468
Y
Y
Q
A
R
L
L
S
L
R
M
K
T
C
T
Site 34
T473
L
L
S
L
R
M
K
T
C
T
Q
A
A
S
H
Site 35
T475
S
L
R
M
K
T
C
T
Q
A
A
S
H
S
G
Site 36
Y496
K
A
V
K
I
I
A
Y
K
N
G
D
G
Y
R
Site 37
Y502
A
Y
K
N
G
D
G
Y
R
N
G
K
L
I
V
Site 38
S531
L
G
L
A
R
A
A
S
K
V
Y
T
K
D
G
Site 39
T535
R
A
A
S
K
V
Y
T
K
D
G
T
P
I
F
Site 40
T539
K
V
Y
T
K
D
G
T
P
I
F
T
L
R
D
Site 41
S555
V
L
W
A
L
D
E
S
F
L
Q
R
D
S
E
Site 42
S561
E
S
F
L
Q
R
D
S
E
K
Q
K
Q
D
A
Site 43
S594
K
N
R
L
F
A
K
S
V
T
S
D
S
L
D
Site 44
S599
A
K
S
V
T
S
D
S
L
D
G
I
D
K
S
Site 45
S632
P
F
L
P
P
N
E
S
R
K
I
R
E
T
E
Site 46
T638
E
S
R
K
I
R
E
T
E
L
A
K
K
G
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation