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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCDC129
Full Name:
Coiled-coil domain-containing protein 129
Alias:
Type:
Mass (Da):
98946
Number AA:
896
UniProt ID:
Q6ZRS4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
L
Q
E
G
Q
E
K
S
K
R
E
I
L
K
C
Site 2
S29
E
I
L
K
C
T
K
S
A
W
A
P
L
D
E
Site 3
S46
P
P
D
P
E
E
E
S
Q
S
L
T
I
P
M
Site 4
S48
D
P
E
E
E
S
Q
S
L
T
I
P
M
L
E
Site 5
T50
E
E
E
S
Q
S
L
T
I
P
M
L
E
D
S
Site 6
S57
T
I
P
M
L
E
D
S
K
Q
E
S
I
Q
Q
Site 7
S61
L
E
D
S
K
Q
E
S
I
Q
Q
W
L
D
S
Site 8
S68
S
I
Q
Q
W
L
D
S
G
F
F
V
S
A
N
Site 9
S73
L
D
S
G
F
F
V
S
A
N
E
N
F
Q
Q
Site 10
T85
F
Q
Q
V
I
D
R
T
V
S
L
Y
E
Q
G
Site 11
S87
Q
V
I
D
R
T
V
S
L
Y
E
Q
G
M
V
Site 12
Y89
I
D
R
T
V
S
L
Y
E
Q
G
M
V
Q
M
Site 13
Y101
V
Q
M
T
V
K
D
Y
M
R
S
L
H
Q
F
Site 14
S109
M
R
S
L
H
Q
F
S
E
T
P
I
L
S
R
Site 15
T111
S
L
H
Q
F
S
E
T
P
I
L
S
R
G
T
Site 16
S115
F
S
E
T
P
I
L
S
R
G
T
S
F
N
S
Site 17
T118
T
P
I
L
S
R
G
T
S
F
N
S
C
Y
S
Site 18
S119
P
I
L
S
R
G
T
S
F
N
S
C
Y
S
T
Site 19
S122
S
R
G
T
S
F
N
S
C
Y
S
T
A
S
V
Site 20
Y124
G
T
S
F
N
S
C
Y
S
T
A
S
V
P
Q
Site 21
S125
T
S
F
N
S
C
Y
S
T
A
S
V
P
Q
S
Site 22
T126
S
F
N
S
C
Y
S
T
A
S
V
P
Q
S
I
Site 23
S128
N
S
C
Y
S
T
A
S
V
P
Q
S
I
P
E
Site 24
S132
S
T
A
S
V
P
Q
S
I
P
E
W
L
E
F
Site 25
Y199
D
I
E
N
P
N
L
Y
G
R
F
R
Q
L
E
Site 26
S216
D
H
V
T
N
A
F
S
S
L
L
S
D
V
S
Site 27
S223
S
S
L
L
S
D
V
S
I
L
P
N
R
A
E
Site 28
S237
E
E
K
A
G
G
E
S
V
Q
R
T
S
V
Q
Site 29
T241
G
G
E
S
V
Q
R
T
S
V
Q
S
F
E
E
Site 30
S242
G
E
S
V
Q
R
T
S
V
Q
S
F
E
E
E
Site 31
S245
V
Q
R
T
S
V
Q
S
F
E
E
E
T
G
N
Site 32
T257
T
G
N
P
L
D
M
T
S
G
T
V
G
A
R
Site 33
S258
G
N
P
L
D
M
T
S
G
T
V
G
A
R
V
Site 34
T260
P
L
D
M
T
S
G
T
V
G
A
R
V
D
R
Site 35
S270
A
R
V
D
R
A
N
S
C
Q
S
D
S
S
G
Site 36
S273
D
R
A
N
S
C
Q
S
D
S
S
G
F
L
E
Site 37
S275
A
N
S
C
Q
S
D
S
S
G
F
L
E
E
P
Site 38
S292
P
L
P
L
Q
M
P
S
L
P
N
S
Q
S
P
Site 39
S296
Q
M
P
S
L
P
N
S
Q
S
P
A
E
N
G
Site 40
S298
P
S
L
P
N
S
Q
S
P
A
E
N
G
G
R
Site 41
S311
G
R
K
P
R
D
Q
S
H
S
L
V
S
S
Q
Site 42
S313
K
P
R
D
Q
S
H
S
L
V
S
S
Q
D
C
Site 43
S317
Q
S
H
S
L
V
S
S
Q
D
C
Q
L
E
S
Site 44
S324
S
Q
D
C
Q
L
E
S
D
G
P
D
S
K
S
Site 45
S329
L
E
S
D
G
P
D
S
K
S
R
A
S
M
S
Site 46
S331
S
D
G
P
D
S
K
S
R
A
S
M
S
F
S
Site 47
S334
P
D
S
K
S
R
A
S
M
S
F
S
S
Q
E
Site 48
S336
S
K
S
R
A
S
M
S
F
S
S
Q
E
V
N
Site 49
S338
S
R
A
S
M
S
F
S
S
Q
E
V
N
A
L
Site 50
S339
R
A
S
M
S
F
S
S
Q
E
V
N
A
L
E
Site 51
S350
N
A
L
E
Q
R
A
S
V
S
V
M
E
E
E
Site 52
S352
L
E
Q
R
A
S
V
S
V
M
E
E
E
F
L
Site 53
T379
P
D
M
A
C
A
K
T
T
T
R
G
E
C
P
Site 54
S390
G
E
C
P
R
K
D
S
H
L
W
Q
L
L
P
Site 55
Y403
L
P
M
P
H
A
E
Y
E
V
T
R
P
T
A
Site 56
T406
P
H
A
E
Y
E
V
T
R
P
T
A
T
S
K
Site 57
T409
E
Y
E
V
T
R
P
T
A
T
S
K
Y
D
H
Site 58
S412
V
T
R
P
T
A
T
S
K
Y
D
H
P
L
G
Site 59
Y414
R
P
T
A
T
S
K
Y
D
H
P
L
G
F
M
Site 60
S431
H
V
T
E
M
Q
D
S
F
V
R
P
E
G
A
Site 61
S443
E
G
A
G
K
V
Q
S
H
H
N
E
S
Q
R
Site 62
S448
V
Q
S
H
H
N
E
S
Q
R
S
P
G
N
D
Site 63
S451
H
H
N
E
S
Q
R
S
P
G
N
D
H
T
Q
Site 64
T457
R
S
P
G
N
D
H
T
Q
D
K
F
L
H
V
Site 65
S466
D
K
F
L
H
V
D
S
E
A
P
R
E
E
E
Site 66
S475
A
P
R
E
E
E
S
S
G
F
C
P
H
T
N
Site 67
T481
S
S
G
F
C
P
H
T
N
H
S
L
L
V
P
Site 68
S484
F
C
P
H
T
N
H
S
L
L
V
P
E
S
S
Site 69
S490
H
S
L
L
V
P
E
S
S
S
Q
C
I
P
K
Site 70
S491
S
L
L
V
P
E
S
S
S
Q
C
I
P
K
H
Site 71
S492
L
L
V
P
E
S
S
S
Q
C
I
P
K
H
S
Site 72
T502
I
P
K
H
S
E
I
T
P
Y
A
T
D
L
A
Site 73
Y504
K
H
S
E
I
T
P
Y
A
T
D
L
A
Q
T
Site 74
S531
G
D
P
A
Q
V
K
S
R
S
G
T
L
G
Q
Site 75
S533
P
A
Q
V
K
S
R
S
G
T
L
G
Q
I
L
Site 76
T535
Q
V
K
S
R
S
G
T
L
G
Q
I
L
P
G
Site 77
T543
L
G
Q
I
L
P
G
T
E
A
E
M
E
N
L
Site 78
S556
N
L
P
L
N
T
G
S
S
R
S
V
M
T
Q
Site 79
S557
L
P
L
N
T
G
S
S
R
S
V
M
T
Q
M
Site 80
S559
L
N
T
G
S
S
R
S
V
M
T
Q
M
S
S
Site 81
T562
G
S
S
R
S
V
M
T
Q
M
S
S
S
L
V
Site 82
S586
G
T
G
P
R
G
T
S
L
E
C
T
V
C
D
Site 83
T604
A
T
E
T
R
L
G
T
K
A
R
Q
L
N
D
Site 84
S613
A
R
Q
L
N
D
A
S
I
Q
T
S
A
L
S
Site 85
S617
N
D
A
S
I
Q
T
S
A
L
S
N
K
T
L
Site 86
S620
S
I
Q
T
S
A
L
S
N
K
T
L
T
H
G
Site 87
T623
T
S
A
L
S
N
K
T
L
T
H
G
P
Q
P
Site 88
T625
A
L
S
N
K
T
L
T
H
G
P
Q
P
L
T
Site 89
T632
T
H
G
P
Q
P
L
T
K
S
V
S
L
D
S
Site 90
S634
G
P
Q
P
L
T
K
S
V
S
L
D
S
G
F
Site 91
S636
Q
P
L
T
K
S
V
S
L
D
S
G
F
S
S
Site 92
S639
T
K
S
V
S
L
D
S
G
F
S
S
I
C
P
Site 93
S673
H
C
H
G
E
R
Q
S
P
G
P
E
P
S
V
Site 94
S679
Q
S
P
G
P
E
P
S
V
C
R
H
C
L
C
Site 95
T706
T
L
K
A
L
Q
D
T
T
V
R
E
L
C
S
Site 96
T707
L
K
A
L
Q
D
T
T
V
R
E
L
C
S
C
Site 97
S728
A
M
K
T
I
C
Q
S
F
R
E
Y
L
E
E
Site 98
Y732
I
C
Q
S
F
R
E
Y
L
E
E
I
E
Q
H
Site 99
S748
M
G
Q
Q
A
L
F
S
R
D
M
S
E
E
E
Site 100
S752
A
L
F
S
R
D
M
S
E
E
E
R
E
E
A
Site 101
T764
E
E
A
E
Q
L
Q
T
L
R
E
A
L
R
Q
Site 102
T799
L
L
Q
L
E
V
L
T
A
E
P
P
E
H
Y
Site 103
T822
I
E
E
S
N
G
Q
T
S
C
S
K
I
H
P
Site 104
S823
E
E
S
N
G
Q
T
S
C
S
K
I
H
P
G
Site 105
T835
H
P
G
M
A
P
R
T
V
F
P
P
D
D
G
Site 106
S848
D
G
Q
E
A
P
C
S
G
G
T
Q
L
A
A
Site 107
T857
G
T
Q
L
A
A
F
T
P
P
T
L
E
N
S
Site 108
T860
L
A
A
F
T
P
P
T
L
E
N
S
T
R
M
Site 109
S864
T
P
P
T
L
E
N
S
T
R
M
S
P
S
S
Site 110
S868
L
E
N
S
T
R
M
S
P
S
S
S
A
W
A
Site 111
S870
N
S
T
R
M
S
P
S
S
S
A
W
A
K
L
Site 112
S871
S
T
R
M
S
P
S
S
S
A
W
A
K
L
G
Site 113
S872
T
R
M
S
P
S
S
S
A
W
A
K
L
G
P
Site 114
S883
K
L
G
P
T
P
L
S
N
C
P
V
G
E
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation