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Updated November 2019
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Protein Info
Short Name:
BEND4
Full Name:
BEN domain-containing protein 4
Alias:
CCDC4; Coiled-coil domain-containing protein 4
Type:
CCDC4
Mass (Da):
57856
Number AA:
530
UniProt ID:
Q6ZU67
International Prot ID:
IPI00410472
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
Q
P
A
E
E
G
P
S
V
P
K
I
Y
K
Q
Site 2
Y14
G
P
S
V
P
K
I
Y
K
Q
R
S
P
Y
S
Site 3
S18
P
K
I
Y
K
Q
R
S
P
Y
S
V
L
K
T
Site 4
Y20
I
Y
K
Q
R
S
P
Y
S
V
L
K
T
F
P
Site 5
S21
Y
K
Q
R
S
P
Y
S
V
L
K
T
F
P
S
Site 6
T25
S
P
Y
S
V
L
K
T
F
P
S
K
R
P
A
Site 7
S28
S
V
L
K
T
F
P
S
K
R
P
A
L
A
K
Site 8
Y37
R
P
A
L
A
K
R
Y
E
R
P
T
L
V
E
Site 9
T41
A
K
R
Y
E
R
P
T
L
V
E
L
P
H
V
Site 10
S65
F
A
P
H
A
A
V
S
I
S
S
S
E
P
P
Site 11
S67
P
H
A
A
V
S
I
S
S
S
E
P
P
P
Q
Site 12
S69
A
A
V
S
I
S
S
S
E
P
P
P
Q
Q
F
Site 13
S80
P
Q
Q
F
Q
A
Q
S
S
Y
P
P
G
P
G
Site 14
S81
Q
Q
F
Q
A
Q
S
S
Y
P
P
G
P
G
R
Site 15
Y82
Q
F
Q
A
Q
S
S
Y
P
P
G
P
G
R
A
Site 16
S94
G
R
A
A
A
A
A
S
S
S
S
P
S
C
T
Site 17
S95
R
A
A
A
A
A
S
S
S
S
P
S
C
T
P
Site 18
S97
A
A
A
A
S
S
S
S
P
S
C
T
P
A
T
Site 19
S99
A
A
S
S
S
S
P
S
C
T
P
A
T
S
Q
Site 20
T101
S
S
S
S
P
S
C
T
P
A
T
S
Q
G
H
Site 21
T104
S
P
S
C
T
P
A
T
S
Q
G
H
L
R
T
Site 22
S105
P
S
C
T
P
A
T
S
Q
G
H
L
R
T
P
Site 23
T111
T
S
Q
G
H
L
R
T
P
A
Q
P
P
P
A
Site 24
S119
P
A
Q
P
P
P
A
S
P
A
A
S
S
S
S
Site 25
S123
P
P
A
S
P
A
A
S
S
S
S
S
F
A
A
Site 26
S149
A
G
T
G
G
T
G
S
D
S
A
S
L
E
L
Site 27
S151
T
G
G
T
G
S
D
S
A
S
L
E
L
S
A
Site 28
S153
G
T
G
S
D
S
A
S
L
E
L
S
A
E
S
Site 29
S157
D
S
A
S
L
E
L
S
A
E
S
R
M
I
L
Site 30
S176
Q
Q
C
S
R
V
L
S
L
L
N
C
G
G
K
Site 31
S187
C
G
G
K
L
L
D
S
N
H
S
Q
S
M
I
Site 32
S190
K
L
L
D
S
N
H
S
Q
S
M
I
S
C
V
Site 33
Y204
V
K
Q
E
G
S
S
Y
N
E
R
Q
E
H
C
Site 34
S219
H
I
G
K
G
V
H
S
Q
T
S
D
N
V
D
Site 35
S222
K
G
V
H
S
Q
T
S
D
N
V
D
I
E
M
Site 36
Y231
N
V
D
I
E
M
Q
Y
M
Q
R
K
Q
Q
T
Site 37
S239
M
Q
R
K
Q
Q
T
S
A
F
L
R
V
F
T
Site 38
Y252
F
T
D
S
L
Q
N
Y
L
L
S
G
S
F
P
Site 39
S255
S
L
Q
N
Y
L
L
S
G
S
F
P
T
P
N
Site 40
S257
Q
N
Y
L
L
S
G
S
F
P
T
P
N
P
S
Site 41
T260
L
L
S
G
S
F
P
T
P
N
P
S
S
A
S
Site 42
S264
S
F
P
T
P
N
P
S
S
A
S
E
Y
G
H
Site 43
S265
F
P
T
P
N
P
S
S
A
S
E
Y
G
H
L
Site 44
S267
T
P
N
P
S
S
A
S
E
Y
G
H
L
A
D
Site 45
S281
D
V
D
P
L
S
T
S
P
V
H
T
L
G
G
Site 46
T285
L
S
T
S
P
V
H
T
L
G
G
W
T
S
P
Site 47
S291
H
T
L
G
G
W
T
S
P
A
T
S
E
S
H
Site 48
T294
G
G
W
T
S
P
A
T
S
E
S
H
G
H
P
Site 49
S295
G
W
T
S
P
A
T
S
E
S
H
G
H
P
S
Site 50
S297
T
S
P
A
T
S
E
S
H
G
H
P
S
S
S
Site 51
S302
S
E
S
H
G
H
P
S
S
S
T
L
P
E
E
Site 52
S303
E
S
H
G
H
P
S
S
S
T
L
P
E
E
E
Site 53
S304
S
H
G
H
P
S
S
S
T
L
P
E
E
E
E
Site 54
Y318
E
E
E
D
E
E
G
Y
C
P
R
C
Q
E
L
Site 55
S345
E
L
R
R
K
L
E
S
I
P
V
P
C
Q
T
Site 56
T377
P
Q
P
A
D
Q
P
T
E
G
S
K
Q
L
L
Site 57
Y387
S
K
Q
L
L
N
N
Y
P
V
Y
I
T
S
K
Site 58
Y390
L
L
N
N
Y
P
V
Y
I
T
S
K
Q
W
D
Site 59
S402
Q
W
D
E
A
V
N
S
S
K
K
D
G
R
R
Site 60
Y426
F
T
T
D
E
L
K
Y
S
C
G
L
G
K
R
Site 61
S427
T
T
D
E
L
K
Y
S
C
G
L
G
K
R
K
Site 62
S436
G
L
G
K
R
K
R
S
V
Q
S
G
E
T
G
Site 63
T498
R
Q
G
R
A
V
G
T
F
L
H
N
G
G
S
Site 64
S515
E
G
I
D
H
Q
A
S
Q
D
E
V
F
N
K
Site 65
S523
Q
D
E
V
F
N
K
S
S
Q
D
G
S
G
D
Site 66
S524
D
E
V
F
N
K
S
S
Q
D
G
S
G
D
_
Site 67
S528
N
K
S
S
Q
D
G
S
G
D
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation