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Updated November 2019
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Protein Info
Short Name:
C9orf79
Full Name:
FAM75-like protein C9orf79
Alias:
Type:
Mass (Da):
157136
Number AA:
1445
UniProt ID:
Q6ZUB1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
G
R
A
G
R
V
E
S
G
Q
R
I
P
P
P
Site 2
S30
P
P
P
A
P
R
P
S
V
E
C
T
G
D
D
Site 3
T34
P
R
P
S
V
E
C
T
G
D
D
I
A
L
Q
Site 4
S51
K
M
L
F
P
L
K
S
P
S
A
T
W
L
S
Site 5
S53
L
F
P
L
K
S
P
S
A
T
W
L
S
P
S
Site 6
T55
P
L
K
S
P
S
A
T
W
L
S
P
S
S
T
Site 7
S58
S
P
S
A
T
W
L
S
P
S
S
T
P
W
M
Site 8
S60
S
A
T
W
L
S
P
S
S
T
P
W
M
M
D
Site 9
S88
L
L
L
L
Y
V
H
S
D
P
P
S
P
P
P
Site 10
S92
Y
V
H
S
D
P
P
S
P
P
P
G
R
K
R
Site 11
S100
P
P
P
G
R
K
R
S
S
R
E
P
Q
R
E
Site 12
S101
P
P
G
R
K
R
S
S
R
E
P
Q
R
E
R
Site 13
S109
R
E
P
Q
R
E
R
S
G
R
S
R
S
R
K
Site 14
S112
Q
R
E
R
S
G
R
S
R
S
R
K
I
S
A
Site 15
S114
E
R
S
G
R
S
R
S
R
K
I
S
A
L
K
Site 16
S118
R
S
R
S
R
K
I
S
A
L
K
A
C
R
I
Site 17
T133
L
L
R
E
L
E
E
T
R
D
L
N
Y
L
L
Site 18
Y138
E
E
T
R
D
L
N
Y
L
L
E
S
H
L
R
Site 19
S152
R
K
L
A
G
E
G
S
S
H
L
P
L
G
G
Site 20
S153
K
L
A
G
E
G
S
S
H
L
P
L
G
G
D
Site 21
S185
G
K
C
M
Q
D
P
S
P
A
S
L
S
P
P
Site 22
S188
M
Q
D
P
S
P
A
S
L
S
P
P
A
P
P
Site 23
S190
D
P
S
P
A
S
L
S
P
P
A
P
P
A
P
Site 24
T201
P
P
A
P
L
A
S
T
L
S
P
G
P
M
T
Site 25
T208
T
L
S
P
G
P
M
T
F
S
E
P
F
G
P
Site 26
S210
S
P
G
P
M
T
F
S
E
P
F
G
P
H
S
Site 27
S217
S
E
P
F
G
P
H
S
T
L
S
A
S
G
P
Site 28
T218
E
P
F
G
P
H
S
T
L
S
A
S
G
P
P
Site 29
S220
F
G
P
H
S
T
L
S
A
S
G
P
P
E
P
Site 30
S222
P
H
S
T
L
S
A
S
G
P
P
E
P
L
L
Site 31
S245
P
H
V
V
F
P
P
S
P
Q
P
H
G
P
L
Site 32
S254
Q
P
H
G
P
L
A
S
S
P
P
P
P
D
S
Site 33
S255
P
H
G
P
L
A
S
S
P
P
P
P
D
S
S
Site 34
S261
S
S
P
P
P
P
D
S
S
L
A
G
L
Q
C
Site 35
S262
S
P
P
P
P
D
S
S
L
A
G
L
Q
C
G
Site 36
T271
A
G
L
Q
C
G
S
T
T
C
P
V
P
Q
S
Site 37
S278
T
T
C
P
V
P
Q
S
S
P
L
H
N
Q
V
Site 38
S279
T
C
P
V
P
Q
S
S
P
L
H
N
Q
V
L
Site 39
S294
P
P
P
T
R
V
I
S
G
L
G
C
S
S
D
Site 40
Y307
S
D
P
I
W
D
L
Y
C
W
R
E
A
A
T
Site 41
S319
A
A
T
T
W
G
L
S
T
Y
S
H
G
K
S
Site 42
S322
T
W
G
L
S
T
Y
S
H
G
K
S
Q
P
R
Site 43
S326
S
T
Y
S
H
G
K
S
Q
P
R
H
L
P
D
Site 44
T335
P
R
H
L
P
D
H
T
S
E
A
S
F
W
G
Site 45
S336
R
H
L
P
D
H
T
S
E
A
S
F
W
G
D
Site 46
S339
P
D
H
T
S
E
A
S
F
W
G
D
P
T
P
Site 47
T345
A
S
F
W
G
D
P
T
P
K
H
M
E
V
G
Site 48
S423
L
P
R
P
Q
Q
V
S
D
A
T
T
V
G
N
Site 49
T427
Q
Q
V
S
D
A
T
T
V
G
N
H
L
Q
Q
Site 50
S437
N
H
L
Q
Q
K
R
S
Q
L
F
W
D
L
P
Site 51
S445
Q
L
F
W
D
L
P
S
L
N
S
E
S
L
A
Site 52
S448
W
D
L
P
S
L
N
S
E
S
L
A
T
T
V
Site 53
T453
L
N
S
E
S
L
A
T
T
V
W
V
S
R
N
Site 54
T454
N
S
E
S
L
A
T
T
V
W
V
S
R
N
P
Site 55
S458
L
A
T
T
V
W
V
S
R
N
P
S
S
Q
N
Site 56
S462
V
W
V
S
R
N
P
S
S
Q
N
A
H
S
V
Site 57
S463
W
V
S
R
N
P
S
S
Q
N
A
H
S
V
P
Site 58
S468
P
S
S
Q
N
A
H
S
V
P
L
D
K
A
S
Site 59
S475
S
V
P
L
D
K
A
S
T
S
L
P
G
E
P
Site 60
S477
P
L
D
K
A
S
T
S
L
P
G
E
P
E
V
Site 61
S487
G
E
P
E
V
E
A
S
S
Q
L
S
Q
A
P
Site 62
S491
V
E
A
S
S
Q
L
S
Q
A
P
P
Q
P
H
Site 63
T507
M
A
Q
P
Q
H
F
T
P
A
W
P
Q
S
Q
Site 64
S513
F
T
P
A
W
P
Q
S
Q
P
P
P
L
A
E
Site 65
T523
P
P
L
A
E
I
Q
T
Q
A
H
L
S
P
P
Site 66
S528
I
Q
T
Q
A
H
L
S
P
P
V
P
S
L
G
Site 67
S533
H
L
S
P
P
V
P
S
L
G
C
S
S
P
P
Site 68
S537
P
V
P
S
L
G
C
S
S
P
P
Q
I
R
G
Site 69
S538
V
P
S
L
G
C
S
S
P
P
Q
I
R
G
C
Site 70
S548
Q
I
R
G
C
G
A
S
Y
P
T
S
Q
E
R
Site 71
Y549
I
R
G
C
G
A
S
Y
P
T
S
Q
E
R
T
Site 72
S552
C
G
A
S
Y
P
T
S
Q
E
R
T
Q
S
V
Site 73
T556
Y
P
T
S
Q
E
R
T
Q
S
V
I
P
T
G
Site 74
S558
T
S
Q
E
R
T
Q
S
V
I
P
T
G
K
E
Site 75
T562
R
T
Q
S
V
I
P
T
G
K
E
Y
L
E
W
Site 76
Y566
V
I
P
T
G
K
E
Y
L
E
W
P
L
K
K
Site 77
S583
K
W
K
R
V
L
P
S
L
L
K
K
S
Q
A
Site 78
S588
L
P
S
L
L
K
K
S
Q
A
V
L
S
Q
P
Site 79
S593
K
K
S
Q
A
V
L
S
Q
P
T
A
H
L
P
Site 80
S606
L
P
Q
E
R
P
A
S
W
S
P
K
S
A
P
Site 81
S608
Q
E
R
P
A
S
W
S
P
K
S
A
P
I
L
Site 82
S611
P
A
S
W
S
P
K
S
A
P
I
L
P
G
V
Site 83
S640
N
A
I
H
Q
E
Q
S
C
G
P
P
S
R
L
Site 84
S645
E
Q
S
C
G
P
P
S
R
L
Q
A
S
G
D
Site 85
S650
P
P
S
R
L
Q
A
S
G
D
L
L
Q
P
D
Site 86
S666
E
F
P
G
R
P
Q
S
Q
A
E
D
T
Q
Q
Site 87
T671
P
Q
S
Q
A
E
D
T
Q
Q
A
L
L
P
S
Site 88
S678
T
Q
Q
A
L
L
P
S
Q
P
S
D
F
A
G
Site 89
S681
A
L
L
P
S
Q
P
S
D
F
A
G
K
G
R
Site 90
T694
G
R
K
D
V
Q
K
T
G
F
R
S
S
G
R
Site 91
S698
V
Q
K
T
G
F
R
S
S
G
R
F
S
D
K
Site 92
S699
Q
K
T
G
F
R
S
S
G
R
F
S
D
K
G
Site 93
S703
F
R
S
S
G
R
F
S
D
K
G
C
L
G
S
Site 94
S710
S
D
K
G
C
L
G
S
K
L
G
P
D
P
S
Site 95
S717
S
K
L
G
P
D
P
S
R
D
Q
G
S
G
R
Site 96
S722
D
P
S
R
D
Q
G
S
G
R
T
S
V
K
A
Site 97
S726
D
Q
G
S
G
R
T
S
V
K
A
L
D
E
D
Site 98
S743
A
E
G
D
L
R
R
S
W
K
Y
Q
S
V
S
Site 99
Y746
D
L
R
R
S
W
K
Y
Q
S
V
S
S
T
P
Site 100
S748
R
R
S
W
K
Y
Q
S
V
S
S
T
P
R
D
Site 101
S750
S
W
K
Y
Q
S
V
S
S
T
P
R
D
P
D
Site 102
S751
W
K
Y
Q
S
V
S
S
T
P
R
D
P
D
K
Site 103
T752
K
Y
Q
S
V
S
S
T
P
R
D
P
D
K
E
Site 104
S799
A
K
C
A
V
P
K
S
D
T
H
R
K
P
G
Site 105
T801
C
A
V
P
K
S
D
T
H
R
K
P
G
K
L
Site 106
S810
R
K
P
G
K
L
A
S
W
R
G
G
K
A
H
Site 107
S821
G
K
A
H
V
N
T
S
Q
E
L
S
F
L
H
Site 108
S825
V
N
T
S
Q
E
L
S
F
L
H
P
C
T
Q
Site 109
T850
C
V
R
H
S
W
G
T
D
L
Q
S
L
E
P
Site 110
S854
S
W
G
T
D
L
Q
S
L
E
P
I
N
V
W
Site 111
S873
Q
A
P
P
F
P
Q
S
T
F
T
P
W
A
S
Site 112
T874
A
P
P
F
P
Q
S
T
F
T
P
W
A
S
W
Site 113
T876
P
F
P
Q
S
T
F
T
P
W
A
S
W
V
S
Site 114
S880
S
T
F
T
P
W
A
S
W
V
S
R
V
E
S
Site 115
S883
T
P
W
A
S
W
V
S
R
V
E
S
V
P
K
Site 116
T908
N
G
P
G
D
N
R
T
T
S
K
S
V
P
T
Site 117
T909
G
P
G
D
N
R
T
T
S
K
S
V
P
T
V
Site 118
S910
P
G
D
N
R
T
T
S
K
S
V
P
T
V
S
Site 119
S912
D
N
R
T
T
S
K
S
V
P
T
V
S
G
P
Site 120
S917
S
K
S
V
P
T
V
S
G
P
L
A
A
P
P
Site 121
S937
V
Q
R
P
P
R
G
S
Q
S
A
D
T
H
G
Site 122
S939
R
P
P
R
G
S
Q
S
A
D
T
H
G
R
S
Site 123
T942
R
G
S
Q
S
A
D
T
H
G
R
S
E
A
F
Site 124
T951
G
R
S
E
A
F
P
T
G
H
K
G
R
G
C
Site 125
S959
G
H
K
G
R
G
C
S
Q
P
P
T
C
S
L
Site 126
T963
R
G
C
S
Q
P
P
T
C
S
L
V
G
R
T
Site 127
S965
C
S
Q
P
P
T
C
S
L
V
G
R
T
W
Q
Site 128
S973
L
V
G
R
T
W
Q
S
R
T
V
L
E
S
G
Site 129
T975
G
R
T
W
Q
S
R
T
V
L
E
S
G
K
P
Site 130
S979
Q
S
R
T
V
L
E
S
G
K
P
K
P
R
L
Site 131
S989
P
K
P
R
L
E
G
S
M
G
S
E
M
A
G
Site 132
S1003
G
N
E
A
W
L
E
S
E
S
M
S
P
G
D
Site 133
S1005
E
A
W
L
E
S
E
S
M
S
P
G
D
P
C
Site 134
S1007
W
L
E
S
E
S
M
S
P
G
D
P
C
S
S
Site 135
S1013
M
S
P
G
D
P
C
S
S
R
A
L
Q
V
L
Site 136
S1014
S
P
G
D
P
C
S
S
R
A
L
Q
V
L
S
Site 137
S1021
S
R
A
L
Q
V
L
S
I
G
S
Q
W
A
R
Site 138
T1044
K
V
G
E
K
P
P
T
W
E
V
T
L
G
A
Site 139
T1048
K
P
P
T
W
E
V
T
L
G
A
S
V
R
A
Site 140
S1052
W
E
V
T
L
G
A
S
V
R
A
S
S
G
S
Site 141
S1056
L
G
A
S
V
R
A
S
S
G
S
V
Q
E
D
Site 142
S1057
G
A
S
V
R
A
S
S
G
S
V
Q
E
D
L
Site 143
S1059
S
V
R
A
S
S
G
S
V
Q
E
D
L
R
S
Site 144
S1066
S
V
Q
E
D
L
R
S
T
G
A
L
G
T
T
Site 145
T1067
V
Q
E
D
L
R
S
T
G
A
L
G
T
T
G
Site 146
T1073
S
T
G
A
L
G
T
T
G
N
P
S
A
S
S
Site 147
S1080
T
G
N
P
S
A
S
S
V
C
V
A
Q
D
P
Site 148
S1108
A
L
I
V
Q
V
D
S
E
E
Q
L
P
G
R
Site 149
T1139
G
R
H
M
D
M
L
T
A
A
D
R
L
P
T
Site 150
T1146
T
A
A
D
R
L
P
T
Q
A
P
L
S
T
S
Site 151
S1151
L
P
T
Q
A
P
L
S
T
S
Q
S
V
S
G
Site 152
S1153
T
Q
A
P
L
S
T
S
Q
S
V
S
G
K
N
Site 153
S1155
A
P
L
S
T
S
Q
S
V
S
G
K
N
M
T
Site 154
S1157
L
S
T
S
Q
S
V
S
G
K
N
M
T
A
S
Site 155
T1162
S
V
S
G
K
N
M
T
A
S
Q
G
P
C
A
Site 156
S1164
S
G
K
N
M
T
A
S
Q
G
P
C
A
L
L
Site 157
S1177
L
L
W
K
G
G
D
S
P
G
Q
Q
E
P
G
Site 158
S1185
P
G
Q
Q
E
P
G
S
P
K
A
K
A
P
Q
Site 159
S1194
K
A
K
A
P
Q
K
S
Q
K
T
L
G
C
A
Site 160
T1212
E
A
H
R
R
P
R
T
G
E
Q
G
H
R
S
Site 161
S1219
T
G
E
Q
G
H
R
S
K
G
P
R
T
S
E
Site 162
T1224
H
R
S
K
G
P
R
T
S
E
A
S
G
R
S
Site 163
S1225
R
S
K
G
P
R
T
S
E
A
S
G
R
S
H
Site 164
S1228
G
P
R
T
S
E
A
S
G
R
S
H
P
A
Q
Site 165
Y1247
G
D
K
Q
E
R
K
Y
N
Q
L
Q
L
E
K
Site 166
T1257
L
Q
L
E
K
G
Q
T
P
P
E
S
H
F
Q
Site 167
S1261
K
G
Q
T
P
P
E
S
H
F
Q
R
K
I
S
Site 168
S1268
S
H
F
Q
R
K
I
S
H
H
P
Q
G
L
H
Site 169
S1299
P
G
A
D
A
F
Q
S
W
G
S
G
P
P
R
Site 170
S1340
L
Q
W
G
R
G
P
S
E
V
N
R
H
K
G
Site 171
S1378
E
M
R
A
L
A
C
S
P
K
A
T
P
K
G
Site 172
T1382
L
A
C
S
P
K
A
T
P
K
G
H
H
C
P
Site 173
S1400
R
G
I
R
D
R
D
S
S
W
A
P
P
P
R
Site 174
S1401
G
I
R
D
R
D
S
S
W
A
P
P
P
R
E
Site 175
S1411
P
P
P
R
E
P
V
S
P
A
G
P
H
H
H
Site 176
S1424
H
H
R
P
R
M
A
S
T
S
G
G
P
H
P
Site 177
S1426
R
P
R
M
A
S
T
S
G
G
P
H
P
Q
L
Site 178
S1438
P
Q
L
Q
E
L
M
S
A
Q
R
C
L
A
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation