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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DKFZp761B107
Full Name:
Coiled-coil domain-containing protein 149
Alias:
Type:
Mass (Da):
52796
Number AA:
474
UniProt ID:
Q6ZUS6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
Q
L
R
E
R
H
Q
S
L
K
K
K
Y
R
E
Site 2
Y16
H
Q
S
L
K
K
K
Y
R
E
L
I
D
G
D
Site 3
S25
E
L
I
D
G
D
P
S
L
P
P
E
K
R
K
Site 4
S43
L
A
Q
L
L
R
D
S
Q
D
R
N
K
H
L
Site 5
T74
D
N
K
L
L
R
M
T
I
A
K
Q
R
L
G
Site 6
S111
R
A
K
E
Q
I
E
S
L
E
H
D
L
Q
A
Site 7
S119
L
E
H
D
L
Q
A
S
V
D
E
L
Q
D
V
Site 8
S132
D
V
K
E
E
R
S
S
Y
Q
D
K
V
E
R
Site 9
Y133
V
K
E
E
R
S
S
Y
Q
D
K
V
E
R
L
Site 10
S149
Q
E
L
N
H
I
L
S
G
H
E
N
R
I
I
Site 11
Y167
A
L
C
M
E
N
R
Y
L
Q
E
R
L
K
Q
Site 12
S184
E
E
V
N
L
L
K
S
N
I
A
K
Y
K
N
Site 13
Y189
L
K
S
N
I
A
K
Y
K
N
A
L
E
R
R
Site 14
S199
A
L
E
R
R
K
N
S
K
G
Q
G
K
S
S
Site 15
S205
N
S
K
G
Q
G
K
S
S
S
S
A
L
T
G
Site 16
S206
S
K
G
Q
G
K
S
S
S
S
A
L
T
G
V
Site 17
S207
K
G
Q
G
K
S
S
S
S
A
L
T
G
V
L
Site 18
T211
K
S
S
S
S
A
L
T
G
V
L
S
A
K
Q
Site 19
S224
K
Q
V
Q
D
L
L
S
E
D
H
G
C
S
L
Site 20
S230
L
S
E
D
H
G
C
S
L
P
A
T
P
Q
S
Site 21
T234
H
G
C
S
L
P
A
T
P
Q
S
I
S
D
L
Site 22
S237
S
L
P
A
T
P
Q
S
I
S
D
L
K
S
L
Site 23
S239
P
A
T
P
Q
S
I
S
D
L
K
S
L
A
T
Site 24
T265
V
I
Q
H
Q
R
Q
T
N
K
I
L
G
N
R
Site 25
T282
E
L
E
K
K
L
R
T
L
E
V
S
G
L
W
Site 26
S286
K
L
R
T
L
E
V
S
G
L
W
S
L
P
G
Site 27
S290
L
E
V
S
G
L
W
S
L
P
G
G
K
D
T
Site 28
T297
S
L
P
G
G
K
D
T
I
L
F
S
D
P
T
Site 29
S301
G
K
D
T
I
L
F
S
D
P
T
L
P
S
G
Site 30
T304
T
I
L
F
S
D
P
T
L
P
S
G
Q
R
S
Site 31
S307
F
S
D
P
T
L
P
S
G
Q
R
S
R
S
P
Site 32
S311
T
L
P
S
G
Q
R
S
R
S
P
L
L
K
F
Site 33
S313
P
S
G
Q
R
S
R
S
P
L
L
K
F
V
E
Site 34
S342
Q
K
Q
E
E
D
E
S
C
A
A
A
E
A
L
Site 35
S362
A
G
R
P
A
V
N
S
P
A
N
Q
S
R
G
Site 36
S378
Q
C
K
L
F
H
P
S
L
P
Q
L
P
S
E
Site 37
S384
P
S
L
P
Q
L
P
S
E
E
E
V
N
S
L
Site 38
S390
P
S
E
E
E
V
N
S
L
G
R
E
I
I
K
Site 39
T399
G
R
E
I
I
K
L
T
K
E
Q
A
A
A
E
Site 40
S414
L
E
E
V
R
R
E
S
P
I
E
G
Q
R
S
Site 41
S421
S
P
I
E
G
Q
R
S
E
T
G
P
A
P
P
Site 42
T423
I
E
G
Q
R
S
E
T
G
P
A
P
P
G
L
Site 43
S439
I
Q
G
E
L
P
K
S
H
L
D
S
F
E
A
Site 44
S443
L
P
K
S
H
L
D
S
F
E
A
S
R
P
A
Site 45
S447
H
L
D
S
F
E
A
S
R
P
A
A
K
A
S
Site 46
S454
S
R
P
A
A
K
A
S
T
P
E
D
G
K
G
Site 47
T455
R
P
A
A
K
A
S
T
P
E
D
G
K
G
I
Site 48
S470
P
E
G
G
G
M
R
S
T
V
K
T
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation