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Updated November 2019
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Protein Info
Short Name:
FAM179A
Full Name:
Protein FAM179A
Alias:
Type:
Mass (Da):
111153
Number AA:
1019
UniProt ID:
Q6ZUX3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T26
Y
C
G
S
I
P
R
T
S
A
G
P
R
V
L
Site 2
S27
C
G
S
I
P
R
T
S
A
G
P
R
V
L
P
Site 3
S37
P
R
V
L
P
P
G
S
I
N
S
S
L
P
H
Site 4
S40
L
P
P
G
S
I
N
S
S
L
P
H
G
E
G
Site 5
S41
P
P
G
S
I
N
S
S
L
P
H
G
E
G
S
Site 6
S48
S
L
P
H
G
E
G
S
L
Q
P
E
P
R
A
Site 7
T79
L
G
G
L
K
L
D
T
P
S
K
G
W
Q
A
Site 8
S98
P
R
N
L
R
A
L
S
L
G
D
Q
P
L
V
Site 9
S109
Q
P
L
V
L
L
P
S
P
E
S
E
A
N
S
Site 10
S112
V
L
L
P
S
P
E
S
E
A
N
S
V
A
R
Site 11
S116
S
P
E
S
E
A
N
S
V
A
R
D
T
I
Q
Site 12
T121
A
N
S
V
A
R
D
T
I
Q
I
K
D
K
L
Site 13
S134
K
L
K
K
R
R
L
S
E
G
L
A
A
S
S
Site 14
S140
L
S
E
G
L
A
A
S
S
R
A
S
L
D
P
Site 15
S141
S
E
G
L
A
A
S
S
R
A
S
L
D
P
G
Site 16
S144
L
A
A
S
S
R
A
S
L
D
P
G
G
G
P
Site 17
S158
P
Q
G
V
P
L
H
S
T
I
P
R
A
T
S
Site 18
T159
Q
G
V
P
L
H
S
T
I
P
R
A
T
S
Q
Site 19
T164
H
S
T
I
P
R
A
T
S
Q
R
L
L
R
V
Site 20
S165
S
T
I
P
R
A
T
S
Q
R
L
L
R
V
P
Site 21
S180
R
P
M
P
L
I
Q
S
I
P
T
T
P
E
A
Site 22
T184
L
I
Q
S
I
P
T
T
P
E
A
S
G
V
K
Site 23
S200
K
G
L
D
L
P
G
S
I
P
G
P
H
E
L
Site 24
S231
N
D
E
K
M
Q
K
S
L
G
A
I
V
I
P
Site 25
T245
P
P
I
P
K
A
R
T
V
A
A
T
P
S
R
Site 26
T249
K
A
R
T
V
A
A
T
P
S
R
V
P
G
S
Site 27
S251
R
T
V
A
A
T
P
S
R
V
P
G
S
L
P
Site 28
S256
T
P
S
R
V
P
G
S
L
P
S
P
L
P
P
Site 29
S259
R
V
P
G
S
L
P
S
P
L
P
P
G
Q
G
Site 30
T269
P
P
G
Q
G
V
L
T
G
L
R
A
P
R
T
Site 31
T276
T
G
L
R
A
P
R
T
R
L
A
R
G
S
G
Site 32
S282
R
T
R
L
A
R
G
S
G
P
R
E
K
T
P
Site 33
T288
G
S
G
P
R
E
K
T
P
A
S
L
E
P
K
Site 34
S291
P
R
E
K
T
P
A
S
L
E
P
K
P
L
A
Site 35
S299
L
E
P
K
P
L
A
S
P
I
R
D
R
P
A
Site 36
S316
K
K
P
A
L
P
F
S
Q
S
A
P
T
L
T
Site 37
T321
P
F
S
Q
S
A
P
T
L
T
A
F
S
F
D
Site 38
T352
I
G
T
K
I
Q
V
T
I
S
K
S
A
R
E
Site 39
S354
T
K
I
Q
V
T
I
S
K
S
A
R
E
K
M
Site 40
S356
I
Q
V
T
I
S
K
S
A
R
E
K
M
Q
L
Site 41
T380
R
R
L
E
E
P
R
T
G
Q
E
L
T
S
Q
Site 42
S386
R
T
G
Q
E
L
T
S
Q
C
L
G
S
Q
R
Site 43
S391
L
T
S
Q
C
L
G
S
Q
R
A
F
M
K
E
Site 44
S410
L
R
G
S
G
T
L
S
V
P
T
R
L
S
G
Site 45
T413
S
G
T
L
S
V
P
T
R
L
S
G
P
C
R
Site 46
S416
L
S
V
P
T
R
L
S
G
P
C
R
N
D
V
Site 47
S435
R
K
W
A
S
R
A
S
L
P
S
I
P
I
S
Site 48
S438
A
S
R
A
S
L
P
S
I
P
I
S
R
Q
E
Site 49
S442
S
L
P
S
I
P
I
S
R
Q
E
P
R
F
A
Site 50
S453
P
R
F
A
R
H
A
S
A
N
S
L
P
A
V
Site 51
T462
N
S
L
P
A
V
L
T
L
G
S
P
E
W
E
Site 52
S465
P
A
V
L
T
L
G
S
P
E
W
E
E
E
E
Site 53
S486
C
K
E
L
R
P
F
S
N
P
E
L
G
L
R
Site 54
S522
Q
R
L
A
A
C
H
S
E
V
L
T
G
K
L
Site 55
S545
G
E
V
T
N
L
R
S
K
V
S
H
L
A
I
Site 56
S595
I
Q
R
A
A
G
Q
S
L
R
A
M
V
E
N
Site 57
Y627
R
N
P
L
I
R
K
Y
A
A
E
H
L
S
A
Site 58
S646
I
G
A
E
K
L
L
S
G
T
R
D
S
T
D
Site 59
S651
L
L
S
G
T
R
D
S
T
D
M
L
V
H
N
Site 60
T652
L
S
G
T
R
D
S
T
D
M
L
V
H
N
L
Site 61
S666
L
V
R
L
A
Q
D
S
N
Q
D
T
R
F
Y
Site 62
T670
A
Q
D
S
N
Q
D
T
R
F
Y
G
R
K
M
Site 63
Y673
S
N
Q
D
T
R
F
Y
G
R
K
M
V
N
I
Site 64
S694
F
D
A
F
L
K
Q
S
L
P
S
Y
D
L
Q
Site 65
Y698
L
K
Q
S
L
P
S
Y
D
L
Q
K
V
M
A
Site 66
S729
K
G
R
K
V
L
R
S
L
V
V
C
E
N
G
Site 67
S755
P
R
L
V
G
L
R
S
T
L
Q
G
R
G
E
Site 68
T756
R
L
V
G
L
R
S
T
L
Q
G
R
G
E
M
Site 69
T771
V
E
Q
L
R
E
L
T
R
L
L
E
A
K
D
Site 70
T812
V
Q
V
F
D
A
F
T
P
R
L
Q
D
S
N
Site 71
T941
N
T
A
T
R
N
G
T
L
P
G
P
S
G
N
Site 72
S946
N
G
T
L
P
G
P
S
G
N
I
R
G
V
V
Site 73
S957
R
G
V
V
C
R
L
S
R
S
L
Q
E
H
M
Site 74
S959
V
V
C
R
L
S
R
S
L
Q
E
H
M
G
S
Site 75
S974
R
L
L
D
F
A
A
S
Q
P
K
H
V
L
K
Site 76
T982
Q
P
K
H
V
L
K
T
L
Q
E
L
L
D
S
Site 77
S989
T
L
Q
E
L
L
D
S
E
S
L
G
G
S
R
Site 78
S991
Q
E
L
L
D
S
E
S
L
G
G
S
R
K
A
Site 79
S995
D
S
E
S
L
G
G
S
R
K
A
T
D
R
G
Site 80
T999
L
G
G
S
R
K
A
T
D
R
G
V
A
P
D
Site 81
S1007
D
R
G
V
A
P
D
S
K
T
T
G
S
S
Y
Site 82
T1009
G
V
A
P
D
S
K
T
T
G
S
S
Y
P
F
Site 83
S1012
P
D
S
K
T
T
G
S
S
Y
P
F
Q
L
D
Site 84
Y1014
S
K
T
T
G
S
S
Y
P
F
Q
L
D
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation