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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DNA-binding protein RFX8
Full Name:
DNA-binding protein RFX8
Alias:
Regulatory factor X 8
Type:
Mass (Da):
66266
Number AA:
586
UniProt ID:
Q6ZV50
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
A
E
G
V
P
A
S
P
S
S
G
E
G
S
Site 2
S10
E
G
V
P
A
S
P
S
S
G
E
G
S
R
G
Site 3
S11
G
V
P
A
S
P
S
S
G
E
G
S
R
G
P
Site 4
S15
S
P
S
S
G
E
G
S
R
G
P
H
S
G
V
Site 5
S20
E
G
S
R
G
P
H
S
G
V
I
Q
W
L
V
Site 6
Y47
R
C
L
M
Y
E
I
Y
V
E
T
C
G
Q
N
Site 7
T63
E
N
Q
V
N
P
A
T
F
G
K
L
V
R
L
Site 8
T77
L
V
F
P
D
L
G
T
R
R
L
G
T
R
G
Site 9
T82
L
G
T
R
R
L
G
T
R
G
S
A
R
Y
H
Site 10
S85
R
R
L
G
T
R
G
S
A
R
Y
H
Y
D
G
Site 11
Y88
G
T
R
G
S
A
R
Y
H
Y
D
G
I
C
I
Site 12
Y90
R
G
S
A
R
Y
H
Y
D
G
I
C
I
K
K
Site 13
Y105
S
S
F
F
Y
A
Q
Y
C
Y
L
I
G
E
K
Site 14
Y107
F
F
Y
A
Q
Y
C
Y
L
I
G
E
K
R
Y
Site 15
S116
I
G
E
K
R
Y
H
S
G
D
A
I
A
F
E
Site 16
S142
E
A
T
C
E
D
H
S
P
M
K
T
D
P
V
Site 17
T146
E
D
H
S
P
M
K
T
D
P
V
G
S
P
L
Site 18
S151
M
K
T
D
P
V
G
S
P
L
S
E
F
R
R
Site 19
S154
D
P
V
G
S
P
L
S
E
F
R
R
C
P
F
Site 20
Y170
E
Q
E
Q
A
K
K
Y
S
C
N
M
M
A
F
Site 21
Y182
M
A
F
L
A
D
E
Y
C
N
Y
C
R
D
I
Site 22
Y185
L
A
D
E
Y
C
N
Y
C
R
D
I
L
R
N
Site 23
T198
R
N
V
E
D
L
L
T
S
F
W
K
S
L
Q
Site 24
S199
N
V
E
D
L
L
T
S
F
W
K
S
L
Q
Q
Site 25
S203
L
L
T
S
F
W
K
S
L
Q
Q
D
T
V
M
Site 26
T208
W
K
S
L
Q
Q
D
T
V
M
L
M
S
L
P
Site 27
Y229
K
C
Y
D
V
Q
L
Y
K
G
I
E
D
V
L
Site 28
S251
V
S
I
Q
Y
L
K
S
V
Q
L
F
S
K
K
Site 29
S277
V
P
A
L
L
Q
I
S
K
L
K
E
V
T
L
Site 30
T293
V
K
R
L
R
R
K
T
Y
L
S
N
M
A
K
Site 31
Y294
K
R
L
R
R
K
T
Y
L
S
N
M
A
K
T
Site 32
S296
L
R
R
K
T
Y
L
S
N
M
A
K
T
M
R
Site 33
T301
Y
L
S
N
M
A
K
T
M
R
M
V
L
K
S
Site 34
S308
T
M
R
M
V
L
K
S
K
R
R
V
S
V
L
Site 35
S313
L
K
S
K
R
R
V
S
V
L
K
S
D
L
Q
Site 36
S317
R
R
V
S
V
L
K
S
D
L
Q
A
I
I
N
Site 37
S337
T
S
K
K
A
L
A
S
D
R
S
G
A
D
E
Site 38
S340
K
A
L
A
S
D
R
S
G
A
D
E
L
E
N
Site 39
S388
F
V
F
Q
T
S
R
S
K
E
E
F
T
K
L
Site 40
S398
E
F
T
K
L
A
A
S
F
Q
L
R
W
N
L
Site 41
T415
T
A
V
S
K
A
M
T
L
C
H
R
D
S
F
Site 42
T455
E
E
E
E
D
M
G
T
V
K
E
M
L
P
D
Site 43
T465
E
M
L
P
D
D
P
T
L
G
Q
P
D
Q
A
Site 44
S476
P
D
Q
A
L
F
H
S
L
N
S
S
L
S
Q
Site 45
S482
H
S
L
N
S
S
L
S
Q
A
C
A
S
P
S
Site 46
S487
S
L
S
Q
A
C
A
S
P
S
M
E
P
L
G
Site 47
T498
E
P
L
G
V
M
P
T
H
M
G
Q
G
R
Y
Site 48
Y505
T
H
M
G
Q
G
R
Y
P
V
G
V
S
N
M
Site 49
T538
Q
V
L
L
E
D
E
T
T
E
S
A
V
K
L
Site 50
T539
V
L
L
E
D
E
T
T
E
S
A
V
K
L
S
Site 51
S541
L
E
D
E
T
T
E
S
A
V
K
L
S
L
P
Site 52
T556
M
G
Q
E
A
L
I
T
L
K
D
G
Q
Q
F
Site 53
S568
Q
Q
F
V
I
Q
I
S
D
V
P
Q
S
S
E
Site 54
S573
Q
I
S
D
V
P
Q
S
S
E
D
I
Y
F
R
Site 55
Y578
P
Q
S
S
E
D
I
Y
F
R
E
N
N
A
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation