PhosphoNET

           
Protein Info 
   
Short Name:  PHLPP2
Full Name:  PH domain leucine-rich repeat-containing protein phosphatase 2
Alias:  PH domain leucine-rich repeat-containing protein phosphatase-like
Type: 
Mass (Da):  146751
Number AA:  1323
UniProt ID:  Q6ZVD8
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S6__MKRNGSRNCLNRR
Site 2S14RNCLNRRSRFGSRER
Site 3S18NRRSRFGSRERDWLR
Site 4Y34DVKRGCVYLYGADTT
Site 5Y36KRGCVYLYGADTTTA
Site 6T40VYLYGADTTTATTTT
Site 7T46DTTTATTTTTTSSSS
Site 8T47TTTATTTTTTSSSSS
Site 9T48TTATTTTTTSSSSSS
Site 10T49TATTTTTTSSSSSSS
Site 11S50ATTTTTTSSSSSSSS
Site 12S51TTTTTTSSSSSSSSS
Site 13S52TTTTTSSSSSSSSSS
Site 14S53TTTTSSSSSSSSSSS
Site 15S54TTTSSSSSSSSSSSD
Site 16S55TTSSSSSSSSSSSDL
Site 17S56TSSSSSSSSSSSDLH
Site 18S57SSSSSSSSSSSDLHL
Site 19S58SSSSSSSSSSDLHLV
Site 20S59SSSSSSSSSDLHLVL
Site 21S60SSSSSSSSDLHLVLC
Site 22S84CAGEGRESLYLQLHG
Site 23Y86GEGRESLYLQLHGDL
Site 24T100LVRRLEPTERPLQIV
Site 25Y108ERPLQIVYDYLSRLG
Site 26S112QIVYDYLSRLGFDDP
Site 27S154RLDRILLSGIYNVRK
Site 28Y157RILLSGIYNVRKGKT
Site 29T191SSVKDCQTGKMHILP
Site 30Y212EEVKRRQYSLAFSSA
Site 31S213EVKRRQYSLAFSSAG
Site 32S217RQYSLAFSSAGAQAQ
Site 33T225SAGAQAQTYHVSFET
Site 34Y226AGAQAQTYHVSFETL
Site 35S229QAQTYHVSFETLAEY
Site 36Y236SFETLAEYQRWQRQA
Site 37S244QRWQRQASKVVSQRI
Site 38S248RQASKVVSQRISTVD
Site 39S260TVDLSCYSLEEVPEH
Site 40Y270EVPEHLFYSQDITYL
Site 41Y276FYSQDITYLNLRHNF
Site 42T294ERPGGLDTLYKFSQL
Site 43Y296PGGLDTLYKFSQLKG
Site 44S299LDTLYKFSQLKGLNL
Site 45S307QLKGLNLSHNKLGLF
Site 46S330TLTELNLSCNGFHDL
Site 47S339NGFHDLPSQIGNLLN
Site 48T359LDGNFLTTLPEELGN
Site 49S372GNLQQLSSLGISFNN
Site 50S376QLSSLGISFNNFSQI
Site 51S381GISFNNFSQIPEVYE
Site 52T429LRMNHLKTMVIENLE
Site 53T452DLRDNRLTDLDLSSL
Site 54S457RLTDLDLSSLCSLEQ
Site 55T476RNQLRELTLSGFSLR
Site 56T484LSGFSLRTLYASSNR
Site 57Y486GFSLRTLYASSNRLT
Site 58S488SLRTLYASSNRLTAV
Site 59S489LRTLYASSNRLTAVN
Site 60T493YASSNRLTAVNVYPV
Site 61Y598SKALNLRYLNASANS
Site 62S602NLRYLNASANSLESL
Site 63S605YLNASANSLESLPSA
Site 64S608ASANSLESLPSACTG
Site 65S611NSLESLPSACTGEES
Site 66T614ESLPSACTGEESLSM
Site 67T658LANNQLQTFPASKLN
Site 68S662QLQTFPASKLNKLEQ
Site 69S676QLEELNLSGNKLKTI
Site 70T682LSGNKLKTIPTTIAN
Site 71T695ANCKRLHTLVAHSNN
Site 72T764DIFSHITTLKIDQKP
Site 73T775DQKPLPTTDSTVTST
Site 74S777KPLPTTDSTVTSTFW
Site 75T778PLPTTDSTVTSTFWS
Site 76S781TTDSTVTSTFWSHGL
Site 77T782TDSTVTSTFWSHGLA
Site 78Y816AEGVGAVYGMFDGDR
Site 79T850VQQSTNDTVFMANTF
Site 80T856DTVFMANTFLVSHRK
Site 81Y879GSSALLCYIRPDTAD
Site 82T884LCYIRPDTADPASSF
Site 83S889PDTADPASSFSLTVA
Site 84S890DTADPASSFSLTVAN
Site 85S915GGKPVPLSKVFSLEQ
Site 86S919VPLSKVFSLEQDPEE
Site 87T971PKPHISSTPLTIQDE
Site 88S992KALWEHLSYTEAVNA
Site 89T1069KDAPKPATPSSSSGI
Site 90S1071APKPATPSSSSGIAS
Site 91S1072PKPATPSSSSGIASE
Site 92S1073KPATPSSSSGIASEF
Site 93S1074PATPSSSSGIASEFS
Site 94S1078SSSSGIASEFSSEMS
Site 95S1081SGIASEFSSEMSTSE
Site 96S1082GIASEFSSEMSTSEV
Site 97S1085SEFSSEMSTSEVSSE
Site 98T1086EFSSEMSTSEVSSEV
Site 99S1087FSSEMSTSEVSSEVG
Site 100S1091MSTSEVSSEVGSTAS
Site 101S1095EVSSEVGSTASDEHN
Site 102T1096VSSEVGSTASDEHNA
Site 103S1098SEVGSTASDEHNAGG
Site 104S1119PRPERRCSLHPTPTS
Site 105T1123RRCSLHPTPTSGLFQ
Site 106T1125CSLHPTPTSGLFQRQ
Site 107S1126SLHPTPTSGLFQRQP
Site 108S1134GLFQRQPSSATFSSN
Site 109S1135LFQRQPSSATFSSNQ
Site 110T1137QRQPSSATFSSNQSD
Site 111S1139QPSSATFSSNQSDNG
Site 112S1140PSSATFSSNQSDNGL
Site 113S1143ATFSSNQSDNGLDSD
Site 114S1149QSDNGLDSDDDQPVE
Site 115T1160QPVEGVITNGSKVEV
Site 116S1163EGVITNGSKVEVEVD
Site 117S1182RGRDLENSPPLIESS
Site 118S1188NSPPLIESSPTLCSE
Site 119S1189SPPLIESSPTLCSEE
Site 120T1191PLIESSPTLCSEEHA
Site 121S1194ESSPTLCSEEHARGS
Site 122S1201SEEHARGSCFGIRRQ
Site 123S1210FGIRRQNSVNSGMLL
Site 124S1220SGMLLPMSKDRMELQ
Site 125S1229DRMELQKSPSTSCLY
Site 126S1231MELQKSPSTSCLYGK
Site 127S1233LQKSPSTSCLYGKKL
Site 128Y1236SPSTSCLYGKKLSNG
Site 129S1241CLYGKKLSNGSIVPL
Site 130T1259LNLIEVATEVPKRKT
Site 131T1266TEVPKRKTGYFAAPT
Site 132Y1268VPKRKTGYFAAPTQM
Site 133S1301QMKQHQDSRLEPEPH
Site 134T1313EPHEEDRTEPPEEFD
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation