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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MICALCL
Full Name:
MICAL C-terminal-like protein
Alias:
ERK2-binding testicular protein 1;Ebitein-1
Type:
Mass (Da):
77277
Number AA:
695
UniProt ID:
Q6ZW33
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
S
P
P
K
D
P
S
P
S
L
P
L
P
S
Site 2
S10
P
P
K
D
P
S
P
S
L
P
L
P
S
S
S
Site 3
S15
S
P
S
L
P
L
P
S
S
S
S
H
S
S
S
Site 4
S16
P
S
L
P
L
P
S
S
S
S
H
S
S
S
P
Site 5
S17
S
L
P
L
P
S
S
S
S
H
S
S
S
P
P
Site 6
S18
L
P
L
P
S
S
S
S
H
S
S
S
P
P
S
Site 7
S20
L
P
S
S
S
S
H
S
S
S
P
P
S
S
S
Site 8
S21
P
S
S
S
S
H
S
S
S
P
P
S
S
S
S
Site 9
S22
S
S
S
S
H
S
S
S
P
P
S
S
S
S
T
Site 10
S25
S
H
S
S
S
P
P
S
S
S
S
T
S
V
S
Site 11
S26
H
S
S
S
P
P
S
S
S
S
T
S
V
S
G
Site 12
S27
S
S
S
P
P
S
S
S
S
T
S
V
S
G
N
Site 13
S28
S
S
P
P
S
S
S
S
T
S
V
S
G
N
A
Site 14
T29
S
P
P
S
S
S
S
T
S
V
S
G
N
A
P
Site 15
S30
P
P
S
S
S
S
T
S
V
S
G
N
A
P
D
Site 16
S32
S
S
S
S
T
S
V
S
G
N
A
P
D
G
S
Site 17
S39
S
G
N
A
P
D
G
S
S
P
P
Q
M
T
A
Site 18
S40
G
N
A
P
D
G
S
S
P
P
Q
M
T
A
S
Site 19
T45
G
S
S
P
P
Q
M
T
A
S
E
P
L
S
Q
Site 20
S47
S
P
P
Q
M
T
A
S
E
P
L
S
Q
V
S
Site 21
S51
M
T
A
S
E
P
L
S
Q
V
S
R
G
H
P
Site 22
S54
S
E
P
L
S
Q
V
S
R
G
H
P
S
P
P
Site 23
S59
Q
V
S
R
G
H
P
S
P
P
T
P
N
F
R
Site 24
T62
R
G
H
P
S
P
P
T
P
N
F
R
R
R
A
Site 25
Y81
A
P
R
E
I
P
L
Y
L
P
H
H
P
K
P
Site 26
Y93
P
K
P
E
W
A
E
Y
C
L
V
S
P
G
E
Site 27
S97
W
A
E
Y
C
L
V
S
P
G
E
D
G
L
S
Site 28
S104
S
P
G
E
D
G
L
S
D
P
A
E
M
T
S
Site 29
S111
S
D
P
A
E
M
T
S
D
E
C
Q
P
A
E
Site 30
S126
A
P
L
G
D
I
G
S
N
H
R
D
P
H
P
Site 31
S140
P
I
W
G
K
D
R
S
W
T
G
Q
E
L
S
Site 32
T142
W
G
K
D
R
S
W
T
G
Q
E
L
S
P
L
Site 33
S147
S
W
T
G
Q
E
L
S
P
L
A
G
E
D
R
Site 34
T159
E
D
R
E
K
G
S
T
G
A
R
K
E
E
E
Site 35
T184
G
L
K
K
L
V
L
T
Q
E
Q
K
T
M
L
Site 36
S197
M
L
L
D
W
N
D
S
I
P
E
S
V
H
L
Site 37
S201
W
N
D
S
I
P
E
S
V
H
L
K
A
G
E
Site 38
S211
L
K
A
G
E
R
I
S
Q
K
S
A
E
N
G
Site 39
S214
G
E
R
I
S
Q
K
S
A
E
N
G
R
G
G
Site 40
T242
A
A
G
E
P
L
P
T
Q
R
G
A
Q
E
K
Site 41
T252
G
A
Q
E
K
M
G
T
P
A
E
Q
A
Q
G
Site 42
S268
R
N
V
P
P
P
K
S
P
L
R
L
I
A
N
Site 43
S280
I
A
N
A
I
R
R
S
L
E
P
L
L
S
N
Site 44
S286
R
S
L
E
P
L
L
S
N
S
E
G
G
K
K
Site 45
T309
T
L
P
A
Q
A
C
T
R
S
F
S
L
R
K
Site 46
S311
P
A
Q
A
C
T
R
S
F
S
L
R
K
T
N
Site 47
S313
Q
A
C
T
R
S
F
S
L
R
K
T
N
S
N
Site 48
T317
R
S
F
S
L
R
K
T
N
S
N
K
D
G
D
Site 49
S319
F
S
L
R
K
T
N
S
N
K
D
G
D
Q
H
Site 50
S327
N
K
D
G
D
Q
H
S
P
G
R
N
Q
S
S
Site 51
S333
H
S
P
G
R
N
Q
S
S
A
F
S
P
P
D
Site 52
S334
S
P
G
R
N
Q
S
S
A
F
S
P
P
D
P
Site 53
S337
R
N
Q
S
S
A
F
S
P
P
D
P
A
L
R
Site 54
S347
D
P
A
L
R
T
H
S
L
P
N
R
P
S
K
Site 55
S353
H
S
L
P
N
R
P
S
K
V
F
P
A
L
R
Site 56
S361
K
V
F
P
A
L
R
S
P
P
C
S
K
I
E
Site 57
S365
A
L
R
S
P
P
C
S
K
I
E
D
V
P
T
Site 58
T372
S
K
I
E
D
V
P
T
L
L
E
K
V
S
L
Site 59
S378
P
T
L
L
E
K
V
S
L
Q
E
N
F
P
D
Site 60
S387
Q
E
N
F
P
D
A
S
K
P
P
K
K
R
I
Site 61
S395
K
P
P
K
K
R
I
S
L
F
S
S
L
R
L
Site 62
S398
K
K
R
I
S
L
F
S
S
L
R
L
K
D
K
Site 63
S399
K
R
I
S
L
F
S
S
L
R
L
K
D
K
S
Site 64
S406
S
L
R
L
K
D
K
S
F
E
S
F
L
Q
E
Site 65
S409
L
K
D
K
S
F
E
S
F
L
Q
E
S
R
Q
Site 66
S426
D
I
R
D
L
F
G
S
P
K
R
K
V
L
P
Site 67
S449
K
L
L
Q
P
F
K
S
T
S
L
R
Q
A
A
Site 68
S451
L
Q
P
F
K
S
T
S
L
R
Q
A
A
P
P
Site 69
S494
A
Q
V
T
E
A
S
S
S
A
S
S
T
S
S
Site 70
S495
Q
V
T
E
A
S
S
S
A
S
S
T
S
S
S
Site 71
S497
T
E
A
S
S
S
A
S
S
T
S
S
S
S
A
Site 72
S498
E
A
S
S
S
A
S
S
T
S
S
S
S
A
D
Site 73
S500
S
S
S
A
S
S
T
S
S
S
S
A
D
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation