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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KCP
Full Name:
Kielin/chordin-like protein
Alias:
Cysteine-rich BMP regulator 2;Cysteine-rich motor neuron 2 protein;Kielin/chordin-like protein 1
Type:
Mass (Da):
159938
Number AA:
1503
UniProt ID:
Q6ZWJ8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T38
R
E
P
P
G
Q
Q
T
T
A
H
S
S
V
L
Site 2
S43
Q
Q
T
T
A
H
S
S
V
L
A
G
N
S
Q
Site 3
S49
S
S
V
L
A
G
N
S
Q
E
Q
W
H
P
L
Site 4
T79
E
Q
N
K
D
L
Q
T
R
V
R
Q
L
E
S
Site 5
S86
T
R
V
R
Q
L
E
S
C
E
C
H
P
A
S
Site 6
T150
Q
T
Y
G
N
G
E
T
F
S
P
D
A
C
T
Site 7
S152
Y
G
N
G
E
T
F
S
P
D
A
C
T
T
C
Site 8
S174
Q
C
Q
G
P
S
C
S
E
L
N
C
L
E
S
Site 9
S181
S
E
L
N
C
L
E
S
C
T
P
P
G
E
C
Site 10
T183
L
N
C
L
E
S
C
T
P
P
G
E
C
C
P
Site 11
T208
E
H
G
Q
E
W
T
T
P
G
D
P
C
R
I
Site 12
S232
C
R
Q
R
E
C
A
S
L
C
P
Y
P
A
R
Site 13
Y236
E
C
A
S
L
C
P
Y
P
A
R
P
L
P
G
Site 14
S261
L
N
G
R
E
H
R
S
G
E
P
V
G
S
G
Site 15
S267
R
S
G
E
P
V
G
S
G
D
P
C
S
H
C
Site 16
Y312
P
V
C
D
G
C
E
Y
Q
G
H
Q
Y
Q
S
Site 17
Y317
C
E
Y
Q
G
H
Q
Y
Q
S
Q
E
T
F
R
Site 18
T322
H
Q
Y
Q
S
Q
E
T
F
R
L
Q
E
R
G
Site 19
S342
S
C
Q
A
G
E
V
S
C
E
E
Q
E
C
P
Site 20
T351
E
E
Q
E
C
P
V
T
P
C
A
L
P
A
S
Site 21
T387
E
P
D
G
R
P
C
T
A
C
V
C
Q
D
G
Site 22
T412
P
A
P
C
Q
H
P
T
Q
P
P
G
A
C
C
Site 23
Y427
P
S
C
D
S
C
T
Y
H
S
Q
V
Y
A
N
Site 24
S458
Q
D
G
T
V
T
C
S
L
V
D
C
P
P
T
Site 25
T465
S
L
V
D
C
P
P
T
T
C
A
R
P
Q
S
Site 26
T466
L
V
D
C
P
P
T
T
C
A
R
P
Q
S
G
Site 27
S472
T
T
C
A
R
P
Q
S
G
P
G
Q
C
C
P
Site 28
S496
E
V
F
V
D
G
E
S
F
S
H
P
R
D
P
Site 29
S498
F
V
D
G
E
S
F
S
H
P
R
D
P
C
Q
Site 30
Y549
C
A
F
G
G
K
E
Y
P
S
G
A
D
F
P
Site 31
S551
F
G
G
K
E
Y
P
S
G
A
D
F
P
H
P
Site 32
S559
G
A
D
F
P
H
P
S
D
P
C
R
L
C
R
Site 33
Y617
A
H
A
R
H
Q
E
Y
F
S
P
P
G
D
P
Site 34
S619
A
R
H
Q
E
Y
F
S
P
P
G
D
P
C
R
Site 35
Y664
P
S
C
D
G
C
L
Y
Q
G
K
E
F
A
S
Site 36
S671
Y
Q
G
K
E
F
A
S
G
E
R
F
P
S
P
Site 37
S677
A
S
G
E
R
F
P
S
P
T
A
A
C
H
L
Site 38
Y721
P
D
C
D
G
C
E
Y
L
G
E
S
Y
L
S
Site 39
Y726
C
E
Y
L
G
E
S
Y
L
S
N
Q
E
F
P
Site 40
S728
Y
L
G
E
S
Y
L
S
N
Q
E
F
P
D
P
Site 41
S762
P
C
E
P
P
G
C
S
H
P
L
I
P
S
G
Site 42
Y780
P
T
C
Q
G
C
R
Y
H
G
V
T
T
A
S
Site 43
T784
G
C
R
Y
H
G
V
T
T
A
S
G
E
T
L
Site 44
S787
Y
H
G
V
T
T
A
S
G
E
T
L
P
D
P
Site 45
S800
D
P
L
D
P
T
C
S
L
C
T
C
Q
E
G
Site 46
S839
P
V
C
H
S
C
L
S
Q
G
R
E
H
Q
D
Site 47
T884
L
P
C
K
L
Q
V
T
E
R
G
S
C
C
P
Site 48
S888
L
Q
V
T
E
R
G
S
C
C
P
R
C
R
G
Site 49
S907
G
E
E
H
P
E
G
S
R
W
V
P
P
D
S
Site 50
S914
S
R
W
V
P
P
D
S
A
C
S
S
C
V
C
Site 51
S918
P
P
D
S
A
C
S
S
C
V
C
H
E
G
V
Site 52
Y961
C
E
H
E
G
R
K
Y
E
P
G
E
S
F
Q
Site 53
S966
R
K
Y
E
P
G
E
S
F
Q
P
G
A
D
P
Site 54
S988
P
Q
P
E
G
P
P
S
L
R
C
H
R
R
Q
Site 55
S998
C
H
R
R
Q
C
P
S
L
V
G
C
P
P
S
Site 56
S1033
C
S
E
G
L
L
G
S
E
L
A
P
P
D
P
Site 57
Y1042
L
A
P
P
D
P
C
Y
T
C
Q
C
Q
D
L
Site 58
S1062
H
Q
A
C
P
E
L
S
C
P
L
S
E
R
H
Site 59
S1066
P
E
L
S
C
P
L
S
E
R
H
T
P
P
G
Site 60
T1070
C
P
L
S
E
R
H
T
P
P
G
S
C
C
P
Site 61
S1074
E
R
H
T
P
P
G
S
C
C
P
V
C
R
A
Site 62
S1085
V
C
R
A
P
T
Q
S
C
V
H
Q
G
R
E
Site 63
T1100
V
A
S
G
E
R
W
T
V
D
T
C
T
S
C
Site 64
T1113
S
C
S
C
M
A
G
T
V
R
C
Q
S
Q
R
Site 65
S1118
A
G
T
V
R
C
Q
S
Q
R
C
S
P
L
S
Site 66
S1122
R
C
Q
S
Q
R
C
S
P
L
S
C
G
P
D
Site 67
S1125
S
Q
R
C
S
P
L
S
C
G
P
D
K
A
P
Site 68
S1135
P
D
K
A
P
A
L
S
P
G
S
C
C
P
R
Site 69
S1149
R
C
L
P
R
P
A
S
C
M
A
F
G
D
P
Site 70
Y1158
M
A
F
G
D
P
H
Y
R
T
F
D
G
R
L
Site 71
T1160
F
G
D
P
H
Y
R
T
F
D
G
R
L
L
H
Site 72
Y1174
H
F
Q
G
S
C
S
Y
V
L
A
K
D
C
H
Site 73
T1190
G
D
F
S
V
H
V
T
N
D
D
R
G
R
S
Site 74
S1197
T
N
D
D
R
G
R
S
G
V
A
W
T
Q
E
Site 75
T1202
G
R
S
G
V
A
W
T
Q
E
V
A
V
L
L
Site 76
Y1240
F
L
Q
E
P
L
L
Y
V
E
L
R
G
H
T
Site 77
T1247
Y
V
E
L
R
G
H
T
V
I
L
H
A
Q
P
Site 78
S1264
Q
V
L
W
D
G
Q
S
Q
V
E
V
S
V
P
Site 79
S1269
G
Q
S
Q
V
E
V
S
V
P
G
S
Y
Q
G
Site 80
S1273
V
E
V
S
V
P
G
S
Y
Q
G
R
T
C
G
Site 81
S1303
P
E
G
L
L
L
P
S
E
A
A
F
G
N
S
Site 82
S1324
L
W
P
G
R
P
C
S
A
G
R
E
V
D
P
Site 83
S1352
A
R
C
G
V
L
K
S
S
P
F
S
R
C
H
Site 84
S1353
R
C
G
V
L
K
S
S
P
F
S
R
C
H
A
Site 85
S1397
D
A
L
E
A
Y
A
S
H
C
R
Q
A
G
V
Site 86
T1405
H
C
R
Q
A
G
V
T
P
T
W
R
G
P
T
Site 87
T1407
R
Q
A
G
V
T
P
T
W
R
G
P
T
L
C
Site 88
S1494
Q
P
L
G
A
R
P
S
P
S
R
E
P
Q
E
Site 89
S1496
L
G
A
R
P
S
P
S
R
E
P
Q
E
T
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation