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Updated November 2019
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Protein Info
Short Name:
CYP4V2
Full Name:
Cytochrome P450 4V2
Alias:
Type:
Mass (Da):
60724
Number AA:
525
UniProt ID:
Q6ZWL3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S39
S
L
L
Q
R
V
A
S
Y
A
R
K
W
Q
Q
Site 2
T52
Q
Q
M
R
P
I
P
T
V
A
R
A
Y
P
L
Site 3
Y80
F
F
Q
Q
I
I
E
Y
T
E
E
Y
R
H
M
Site 4
T113
E
N
V
E
V
I
L
T
S
S
K
Q
I
D
K
Site 5
S121
S
S
K
Q
I
D
K
S
S
M
Y
K
F
L
E
Site 6
S122
S
K
Q
I
D
K
S
S
M
Y
K
F
L
E
P
Site 7
Y124
Q
I
D
K
S
S
M
Y
K
F
L
E
P
W
L
Site 8
S138
L
G
L
G
L
L
T
S
T
G
N
K
W
R
S
Site 9
S145
S
T
G
N
K
W
R
S
R
R
K
M
L
T
P
Site 10
T151
R
S
R
R
K
M
L
T
P
T
F
H
F
T
I
Site 11
T153
R
R
K
M
L
T
P
T
F
H
F
T
I
L
E
Site 12
S213
G
K
N
I
G
A
Q
S
N
D
D
S
E
Y
V
Site 13
S217
G
A
Q
S
N
D
D
S
E
Y
V
R
A
V
Y
Site 14
Y219
Q
S
N
D
D
S
E
Y
V
R
A
V
Y
R
M
Site 15
Y224
S
E
Y
V
R
A
V
Y
R
M
S
E
M
I
F
Site 16
S289
C
R
G
D
G
R
G
S
A
P
S
K
N
K
R
Site 17
S292
D
G
R
G
S
A
P
S
K
N
K
R
R
A
F
Site 18
S315
D
D
E
G
N
R
L
S
H
E
D
I
R
E
E
Site 19
T325
D
I
R
E
E
V
D
T
F
M
F
E
G
H
D
Site 20
S347
W
S
L
Y
L
L
G
S
N
P
E
V
Q
K
K
Site 21
S366
L
D
D
V
F
G
K
S
D
R
P
A
T
V
E
Site 22
T371
G
K
S
D
R
P
A
T
V
E
D
L
K
K
L
Site 23
Y380
E
D
L
K
K
L
R
Y
L
E
C
V
I
K
E
Site 24
Y411
E
D
C
E
V
A
G
Y
R
V
L
K
G
T
E
Site 25
Y432
A
L
H
R
D
P
R
Y
F
P
N
P
E
E
F
Site 26
Y455
N
A
Q
G
R
H
P
Y
A
Y
V
P
F
S
A
Site 27
Y457
Q
G
R
H
P
Y
A
Y
V
P
F
S
A
G
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation