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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
USP30
Full Name:
Ubiquitin carboxyl-terminal hydrolase 30
Alias:
Deubiquitinating enzyme 30;Ubiquitin thiolesterase 30;Ubiquitin-specific-processing protease 30
Type:
Mass (Da):
58503
Number AA:
517
UniProt ID:
Q70CQ3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T11
S
R
A
E
A
A
M
T
A
A
D
R
A
I
Q
Site 2
Y29
R
T
G
A
A
V
R
Y
K
V
M
K
N
W
G
Site 3
T57
Y
V
I
W
G
P
I
T
E
R
K
K
R
R
K
Site 4
S101
R
W
L
E
E
F
T
S
Q
Y
S
R
D
Q
K
Site 5
Y103
L
E
E
F
T
S
Q
Y
S
R
D
Q
K
E
P
Site 6
S112
R
D
Q
K
E
P
P
S
H
Q
Y
L
S
L
T
Site 7
Y115
K
E
P
P
S
H
Q
Y
L
S
L
T
L
L
H
Site 8
S128
L
H
L
L
K
A
L
S
C
Q
E
V
T
D
D
Site 9
S172
L
F
H
V
I
T
S
S
L
E
D
E
R
D
R
Site 10
T184
R
D
R
Q
P
R
V
T
H
L
F
D
V
H
S
Site 11
S191
T
H
L
F
D
V
H
S
L
E
Q
Q
S
E
I
Site 12
T199
L
E
Q
Q
S
E
I
T
P
K
Q
I
T
C
R
Site 13
T204
E
I
T
P
K
Q
I
T
C
R
T
R
G
S
P
Site 14
S210
I
T
C
R
T
R
G
S
P
H
P
T
S
N
H
Site 15
T214
T
R
G
S
P
H
P
T
S
N
H
W
K
S
Q
Site 16
S215
R
G
S
P
H
P
T
S
N
H
W
K
S
Q
H
Site 17
T247
Q
S
P
V
R
F
D
T
F
D
S
L
S
L
S
Site 18
S275
H
C
L
H
H
F
I
S
S
E
S
V
R
D
V
Site 19
S278
H
H
F
I
S
S
E
S
V
R
D
V
V
C
D
Site 20
T295
T
K
I
E
A
K
G
T
L
N
G
E
K
V
E
Site 21
T306
E
K
V
E
H
Q
R
T
T
F
V
K
Q
L
K
Site 22
T307
K
V
E
H
Q
R
T
T
F
V
K
Q
L
K
L
Site 23
S329
C
I
H
L
Q
R
L
S
W
S
S
H
G
T
P
Site 24
S331
H
L
Q
R
L
S
W
S
S
H
G
T
P
L
K
Site 25
S332
L
Q
R
L
S
W
S
S
H
G
T
P
L
K
R
Site 26
T335
L
S
W
S
S
H
G
T
P
L
K
R
H
E
H
Site 27
Y356
L
M
M
D
I
Y
K
Y
H
L
L
G
H
K
P
Site 28
S364
H
L
L
G
H
K
P
S
Q
H
N
P
K
L
N
Site 29
T388
Q
D
G
P
G
A
P
T
P
V
L
N
Q
P
G
Site 30
T399
N
Q
P
G
A
P
K
T
Q
I
F
M
N
G
A
Site 31
S430
L
P
V
V
P
D
Y
S
S
S
T
Y
L
F
R
Site 32
T455
M
H
S
G
H
F
V
T
Y
R
R
S
P
P
S
Site 33
Y456
H
S
G
H
F
V
T
Y
R
R
S
P
P
S
A
Site 34
S459
H
F
V
T
Y
R
R
S
P
P
S
A
R
N
P
Site 35
S462
T
Y
R
R
S
P
P
S
A
R
N
P
L
S
T
Site 36
S468
P
S
A
R
N
P
L
S
T
S
N
Q
W
L
W
Site 37
T469
S
A
R
N
P
L
S
T
S
N
Q
W
L
W
V
Site 38
T480
W
L
W
V
S
D
D
T
V
R
K
A
S
L
Q
Site 39
S485
D
D
T
V
R
K
A
S
L
Q
E
V
L
S
S
Site 40
S504
L
F
Y
E
R
V
L
S
R
M
Q
H
Q
S
Q
Site 41
S510
L
S
R
M
Q
H
Q
S
Q
E
C
K
S
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation