PhosphoNET

           
Protein Info 
   
Short Name:  USP53
Full Name:  Inactive ubiquitin carboxyl-terminal hydrolase 53
Alias:  Inactive ubiquitin-specific peptidase 53
Type: 
Mass (Da):  120806
Number AA:  1073
UniProt ID:  Q70EK8
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y18GGNLGKVYQPGSMLS
Site 2S22GKVYQPGSMLSLAPT
Site 3S25YQPGSMLSLAPTKGL
Site 4T29SMLSLAPTKGLLNEP
Site 5S59QLDIFRRSLRVLTGH
Site 6T64RRSLRVLTGHVCQGD
Site 7S88IFAQFQHSREKALPS
Site 8S95SREKALPSDNIRHAL
Site 9S105IRHALAESFKDEQRF
Site 10Y160QKFAMTLYEQCVCRS
Site 11S167YEQCVCRSCGASSDP
Site 12S171VCRSCGASSDPLPFT
Site 13T178SSDPLPFTEFVRYIS
Site 14S185TEFVRYISTTALCNE
Site 15Y221AANTTDDYRKCPSNC
Site 16S253TIGLVWDSEHSDLTE
Site 17T259DSEHSDLTEAVVRNL
Site 18Y271RNLATHLYLPGLFYR
Site 19T280PGLFYRVTDENAKNS
Site 20S357NPDGTAVSTEDALRQ
Site 21S367DALRQVISWSHYKSV
Site 22S369LRQVISWSHYKSVAE
Site 23Y371QVISWSHYKSVAENM
Site 24S388EKPVIHKSDNLKENG
Site 25T410RENQKFPTDNISSSN
Site 26S414KFPTDNISSSNRSHS
Site 27S415FPTDNISSSNRSHSH
Site 28S416PTDNISSSNRSHSHT
Site 29S419NISSSNRSHSHTGVG
Site 30S421SSSNRSHSHTGVGKG
Site 31T423SNRSHSHTGVGKGPA
Site 32S433GKGPAKLSHIDQREK
Site 33S445REKIKDISRECALKA
Site 34S461EQKNLLSSQRKDLEK
Site 35S486DLVDEDLSHFQSGSP
Site 36S490EDLSHFQSGSPPAPN
Site 37S492LSHFQSGSPPAPNGF
Site 38Y508QHGNPHLYHSQGKGS
Site 39S510GNPHLYHSQGKGSYK
Site 40S525HDRVVPQSRASAQII
Site 41S528VVPQSRASAQIISSS
Site 42S533RASAQIISSSKSQIL
Site 43S535SAQIISSSKSQILAP
Site 44S537QIISSSKSQILAPGE
Site 45S552KITGKVKSDNGTGYD
Site 46T556KVKSDNGTGYDTDSS
Site 47Y558KSDNGTGYDTDSSQD
Site 48T560DNGTGYDTDSSQDSR
Site 49S562GTGYDTDSSQDSRDR
Site 50S563TGYDTDSSQDSRDRG
Site 51S566DTDSSQDSRDRGNSC
Site 52S572DSRDRGNSCDSSSKS
Site 53S575DRGNSCDSSSKSRNR
Site 54S576RGNSCDSSSKSRNRG
Site 55S577GNSCDSSSKSRNRGW
Site 56S579SCDSSSKSRNRGWKP
Site 57T590GWKPMRETLNVDSIF
Site 58S595RETLNVDSIFSESEK
Site 59S600VDSIFSESEKRQHSP
Site 60S606ESEKRQHSPRHKPNI
Site 61S614PRHKPNISNKPKSSK
Site 62S619NISNKPKSSKDPSFS
Site 63S620ISNKPKSSKDPSFSN
Site 64S624PKSSKDPSFSNWPKE
Site 65S626SSKDPSFSNWPKENP
Site 66S652EMKQEIGSRSSLESN
Site 67S654KQEIGSRSSLESNGK
Site 68S655QEIGSRSSLESNGKG
Site 69S658GSRSSLESNGKGAEK
Site 70S686WQMQRTESGYESSDH
Site 71Y688MQRTESGYESSDHIS
Site 72S690RTESGYESSDHISNG
Site 73S691TESGYESSDHISNGS
Site 74S695YESSDHISNGSTNLD
Site 75T699DHISNGSTNLDSPVI
Site 76S703NGSTNLDSPVIDGNG
Site 77T721DISGVKETVCFSDQI
Site 78S725VKETVCFSDQITTSN
Site 79T729VCFSDQITTSNLNKE
Site 80T741NKERGDCTSLQSQHH
Site 81S742KERGDCTSLQSQHHL
Site 82S745GDCTSLQSQHHLEGF
Site 83S765NLEAGYKSHEFHPES
Site 84S796DNGKLFPSSSLQIPK
Site 85S797NGKLFPSSSLQIPKD
Site 86S798GKLFPSSSLQIPKDH
Site 87S814AREHIHQSDEQKLEK
Site 88S836EWLNIENSERTGLPF
Site 89T839NIENSERTGLPFHVD
Site 90S856ASGKRVNSNEPSSLW
Site 91S860RVNSNEPSSLWSSHL
Site 92S861VNSNEPSSLWSSHLR
Site 93S864NEPSSLWSSHLRTVG
Site 94S865EPSSLWSSHLRTVGL
Site 95T869LWSSHLRTVGLKPET
Site 96Y890QNIMDQCYFENSLST
Site 97S896CYFENSLSTECIIRS
Site 98S903STECIIRSASRSDGC
Site 99S905ECIIRSASRSDGCQM
Site 100S907IIRSASRSDGCQMPK
Site 101Y929PPLPPKKYAITSVPQ
Site 102T932PPKKYAITSVPQSEK
Site 103S933PKKYAITSVPQSEKS
Site 104S937AITSVPQSEKSESTP
Site 105S940SVPQSEKSESTPDVK
Site 106S942PQSEKSESTPDVKLT
Site 107T943QSEKSESTPDVKLTE
Site 108T949STPDVKLTEVFKATS
Site 109S956TEVFKATSHLPKHSL
Site 110S962TSHLPKHSLSTASEP
Site 111S964HLPKHSLSTASEPSL
Site 112S967KHSLSTASEPSLEVS
Site 113S970LSTASEPSLEVSTHM
Site 114S974SEPSLEVSTHMNDER
Site 115T985NDERHKETFQVRECF
Site 116T995VRECFGNTPNCPSSS
Site 117S1000GNTPNCPSSSSTNDF
Site 118S1001NTPNCPSSSSTNDFQ
Site 119S1003PNCPSSSSTNDFQAN
Site 120T1004NCPSSSSTNDFQANS
Site 121S1024FCQPELDSISTCPNE
Site 122S1026QPELDSISTCPNETV
Site 123T1036PNETVSLTTYFSVDS
Site 124T1048VDSCMTDTYRLKYHQ
Site 125Y1049DSCMTDTYRLKYHQR
Site 126Y1053TDTYRLKYHQRPKLS
Site 127S1060YHQRPKLSFPESSGF
Site 128S1064PKLSFPESSGFCNNS
Site 129S1065KLSFPESSGFCNNSL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation