PhosphoNET

           
Protein Info 
   
Short Name:  USP43
Full Name:  Ubiquitin carboxyl-terminal hydrolase 43
Alias:  Deubiquitinating enzyme 43; EC 3.1.2.15; Ubiquitin specific peptidase 43; Ubiquitin thioesterase 43; Ubiquitin-specific-processing protease 43; UBP43
Type:  Phosphoprotein
Mass (Da):  122956
Number AA:  1124
UniProt ID:  Q70EL4
International Prot ID:  IPI00166377
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:  GO:0008234  GO:0004221   PhosphoSite+ KinaseNET
Biological Process:  GO:0006511     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S23PRPRRRRSLRRLFSR
Site 2S37RFLLALGSRSRPGDS
Site 3S39LLALGSRSRPGDSPP
Site 4S44SRSRPGDSPPRPQPG
Site 5S74PVPAAPGSPGEERPP
Site 6Y134EFLALGRYRAAPGRA
Site 7Y159RALWTREYTPQLSAE
Site 8T160ALWTREYTPQLSAEF
Site 9S164REYTPQLSAEFFQNA
Site 10Y175FQNAVSKYGSQFQGN
Site 11S211GSSRGPVSEQLPPEA
Site 12S508KLAVEWDSSVKERLF
Site 13S720SIPPWSASSSMRGST
Site 14S721IPPWSASSSMRGSTS
Site 15S728SSMRGSTSSSLSDHW
Site 16S729SMRGSTSSSLSDHWL
Site 17S754RGSLLSWSSAPCPSL
Site 18S966SFQMGSKSSPPSPYM
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation