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Updated November 2019
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Protein Info
Short Name:
MED13L
Full Name:
Mediator of RNA polymerase II transcription subunit 13-like
Alias:
MD13L; Mediator complex subunit 13-like; Protein similar to TRAP240; Thyroid hormone receptor-associated 2; Thyroid hormone receptor-associated protein complex 240 kDa component-like; TRAP240L
Type:
Mediator complex, Nucleus protein
Mass (Da):
242602
Number AA:
2210
UniProt ID:
Q71F56
International Prot ID:
IPI00400834
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016592
Uniprot
OncoNet
Molecular Function:
GO:0016455
PhosphoSite+
KinaseNET
Biological Process:
GO:0006357
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
A
S
L
E
D
C
H
S
N
L
F
S
L
A
E
Site 2
Y35
T
G
I
K
W
R
R
Y
N
F
G
G
H
G
D
Site 3
S48
G
D
C
G
P
I
I
S
A
P
A
Q
D
D
P
Site 4
S115
G
L
W
E
N
G
L
S
Y
E
C
R
T
L
L
Site 5
Y150
G
K
W
F
V
R
P
Y
E
K
D
E
K
P
V
Site 6
S160
D
E
K
P
V
N
K
S
E
H
L
S
C
A
F
Site 7
T179
H
G
E
S
N
V
C
T
S
V
E
I
A
Q
H
Site 8
Y190
I
A
Q
H
Q
P
I
Y
L
I
N
E
E
H
I
Site 9
T219
S
P
Y
G
L
N
G
T
L
T
G
Q
A
Y
K
Site 10
T221
Y
G
L
N
G
T
L
T
G
Q
A
Y
K
M
S
Site 11
S228
T
G
Q
A
Y
K
M
S
D
P
A
T
R
K
L
Site 12
T232
Y
K
M
S
D
P
A
T
R
K
L
I
E
E
W
Site 13
Y241
K
L
I
E
E
W
Q
Y
F
Y
P
M
V
L
K
Site 14
Y243
I
E
E
W
Q
Y
F
Y
P
M
V
L
K
K
K
Site 15
Y261
K
E
E
D
E
L
G
Y
D
D
D
F
P
V
A
Site 16
S297
N
D
I
P
V
P
Q
S
V
A
S
A
G
G
H
Site 17
S314
V
G
Q
Q
G
L
G
S
V
K
D
P
S
N
C
Site 18
S319
L
G
S
V
K
D
P
S
N
C
G
M
P
L
T
Site 19
T326
S
N
C
G
M
P
L
T
P
P
T
S
P
E
Q
Site 20
S330
M
P
L
T
P
P
T
S
P
E
Q
A
I
L
G
Site 21
S344
G
E
S
G
G
M
Q
S
A
A
S
H
L
V
S
Site 22
S347
G
G
M
Q
S
A
A
S
H
L
V
S
Q
D
G
Site 23
S361
G
G
M
I
T
M
H
S
P
K
R
S
G
K
I
Site 24
S365
T
M
H
S
P
K
R
S
G
K
I
P
P
K
L
Site 25
T389
K
E
C
I
L
N
R
T
Q
S
K
R
S
Q
M
Site 26
S391
C
I
L
N
R
T
Q
S
K
R
S
Q
M
S
T
Site 27
S394
N
R
T
Q
S
K
R
S
Q
M
S
T
P
T
L
Site 28
S397
Q
S
K
R
S
Q
M
S
T
P
T
L
E
E
E
Site 29
T398
S
K
R
S
Q
M
S
T
P
T
L
E
E
E
P
Site 30
T400
R
S
Q
M
S
T
P
T
L
E
E
E
P
A
S
Site 31
S407
T
L
E
E
E
P
A
S
N
P
A
T
W
D
F
Site 32
T411
E
P
A
S
N
P
A
T
W
D
F
V
D
P
T
Site 33
T418
T
W
D
F
V
D
P
T
Q
R
V
S
C
S
C
Site 34
S422
V
D
P
T
Q
R
V
S
C
S
C
S
R
H
K
Site 35
S424
P
T
Q
R
V
S
C
S
C
S
R
H
K
L
L
Site 36
S426
Q
R
V
S
C
S
C
S
R
H
K
L
L
K
R
Site 37
T443
V
G
P
N
R
P
P
T
V
S
Q
P
G
F
S
Site 38
S445
P
N
R
P
P
T
V
S
Q
P
G
F
S
A
G
Site 39
S450
T
V
S
Q
P
G
F
S
A
G
P
S
S
S
S
Site 40
S454
P
G
F
S
A
G
P
S
S
S
S
S
L
P
P
Site 41
S455
G
F
S
A
G
P
S
S
S
S
S
L
P
P
P
Site 42
S456
F
S
A
G
P
S
S
S
S
S
L
P
P
P
A
Site 43
S457
S
A
G
P
S
S
S
S
S
L
P
P
P
A
S
Site 44
S458
A
G
P
S
S
S
S
S
L
P
P
P
A
S
S
Site 45
S464
S
S
L
P
P
P
A
S
S
K
H
K
T
A
E
Site 46
S465
S
L
P
P
P
A
S
S
K
H
K
T
A
E
R
Site 47
T469
P
A
S
S
K
H
K
T
A
E
R
Q
E
K
G
Site 48
S492
I
P
F
H
H
R
P
S
V
A
E
E
L
C
M
Site 49
T503
E
L
C
M
E
Q
D
T
P
G
Q
K
L
G
L
Site 50
S516
G
L
A
G
I
D
S
S
L
E
V
S
S
S
R
Site 51
S520
I
D
S
S
L
E
V
S
S
S
R
K
Y
D
K
Site 52
S521
D
S
S
L
E
V
S
S
S
R
K
Y
D
K
Q
Site 53
S522
S
S
L
E
V
S
S
S
R
K
Y
D
K
Q
M
Site 54
Y525
E
V
S
S
S
R
K
Y
D
K
Q
M
A
V
P
Site 55
T536
M
A
V
P
S
R
N
T
S
K
Q
M
N
L
N
Site 56
S537
A
V
P
S
R
N
T
S
K
Q
M
N
L
N
P
Site 57
S547
M
N
L
N
P
M
D
S
P
H
S
P
I
S
P
Site 58
S550
N
P
M
D
S
P
H
S
P
I
S
P
L
P
P
Site 59
S553
D
S
P
H
S
P
I
S
P
L
P
P
T
L
S
Site 60
T558
P
I
S
P
L
P
P
T
L
S
P
Q
P
R
G
Site 61
S560
S
P
L
P
P
T
L
S
P
Q
P
R
G
Q
E
Site 62
S570
P
R
G
Q
E
T
E
S
L
D
P
P
S
V
P
Site 63
S575
T
E
S
L
D
P
P
S
V
P
V
N
P
A
L
Site 64
T594
L
E
L
Q
Q
L
S
T
L
D
D
R
T
V
L
Site 65
S613
L
P
L
M
A
E
V
S
E
T
A
L
Y
C
G
Site 66
Y618
E
V
S
E
T
A
L
Y
C
G
I
R
P
S
N
Site 67
S624
L
Y
C
G
I
R
P
S
N
P
E
S
S
E
K
Site 68
S628
I
R
P
S
N
P
E
S
S
E
K
W
W
H
S
Site 69
S629
R
P
S
N
P
E
S
S
E
K
W
W
H
S
Y
Site 70
S635
S
S
E
K
W
W
H
S
Y
R
L
P
P
S
D
Site 71
Y636
S
E
K
W
W
H
S
Y
R
L
P
P
S
D
D
Site 72
S641
H
S
Y
R
L
P
P
S
D
D
A
E
F
R
P
Site 73
S702
F
L
D
P
L
P
L
S
Q
Q
P
G
D
S
L
Site 74
S708
L
S
Q
Q
P
G
D
S
L
G
E
V
N
D
P
Site 75
Y716
L
G
E
V
N
D
P
Y
T
F
E
D
G
D
I
Site 76
T717
G
E
V
N
D
P
Y
T
F
E
D
G
D
I
K
Site 77
Y725
F
E
D
G
D
I
K
Y
I
F
T
A
N
K
K
Site 78
T737
N
K
K
C
K
Q
G
T
E
K
D
S
L
K
K
Site 79
S741
K
Q
G
T
E
K
D
S
L
K
K
N
K
S
E
Site 80
S747
D
S
L
K
K
N
K
S
E
D
G
F
G
T
K
Site 81
T757
G
F
G
T
K
D
V
T
T
P
G
H
S
T
P
Site 82
T758
F
G
T
K
D
V
T
T
P
G
H
S
T
P
V
Site 83
S762
D
V
T
T
P
G
H
S
T
P
V
P
D
G
K
Site 84
T763
V
T
T
P
G
H
S
T
P
V
P
D
G
K
N
Site 85
S773
P
D
G
K
N
A
M
S
I
F
S
S
A
T
K
Site 86
S776
K
N
A
M
S
I
F
S
S
A
T
K
T
D
V
Site 87
S777
N
A
M
S
I
F
S
S
A
T
K
T
D
V
R
Site 88
T781
I
F
S
S
A
T
K
T
D
V
R
Q
D
N
A
Site 89
S794
N
A
A
G
R
A
G
S
S
S
L
T
Q
V
T
Site 90
S796
A
G
R
A
G
S
S
S
L
T
Q
V
T
D
L
Site 91
T798
R
A
G
S
S
S
L
T
Q
V
T
D
L
A
P
Site 92
S806
Q
V
T
D
L
A
P
S
L
H
D
L
D
N
I
Site 93
S817
L
D
N
I
F
D
N
S
D
D
D
E
L
G
A
Site 94
S826
D
D
E
L
G
A
V
S
P
A
L
R
S
S
K
Site 95
S832
V
S
P
A
L
R
S
S
K
M
P
A
V
G
T
Site 96
T839
S
K
M
P
A
V
G
T
E
D
R
P
L
G
K
Site 97
Y854
D
G
R
A
A
V
P
Y
P
P
T
V
A
D
L
Site 98
T867
D
L
Q
R
M
F
P
T
P
P
S
L
E
Q
H
Site 99
S870
R
M
F
P
T
P
P
S
L
E
Q
H
P
A
F
Site 100
S878
L
E
Q
H
P
A
F
S
P
V
M
N
Y
K
D
Site 101
Y883
A
F
S
P
V
M
N
Y
K
D
G
I
S
S
E
Site 102
S888
M
N
Y
K
D
G
I
S
S
E
T
V
T
A
L
Site 103
S889
N
Y
K
D
G
I
S
S
E
T
V
T
A
L
G
Site 104
T911
S
M
V
S
T
Q
L
T
E
F
K
M
E
V
E
Site 105
S923
E
V
E
D
G
L
G
S
P
K
P
E
E
I
K
Site 106
S933
P
E
E
I
K
D
F
S
Y
V
H
K
V
P
S
Site 107
Y934
E
E
I
K
D
F
S
Y
V
H
K
V
P
S
F
Site 108
S940
S
Y
V
H
K
V
P
S
F
Q
P
F
V
G
S
Site 109
T992
L
P
M
P
P
A
A
T
F
I
R
D
G
Y
N
Site 110
Y998
A
T
F
I
R
D
G
Y
N
N
V
P
S
V
G
Site 111
S1003
D
G
Y
N
N
V
P
S
V
G
S
L
A
D
P
Site 112
S1006
N
N
V
P
S
V
G
S
L
A
D
P
D
Y
L
Site 113
Y1012
G
S
L
A
D
P
D
Y
L
N
T
P
Q
M
N
Site 114
T1015
A
D
P
D
Y
L
N
T
P
Q
M
N
T
P
V
Site 115
T1020
L
N
T
P
Q
M
N
T
P
V
T
L
N
S
A
Site 116
T1023
P
Q
M
N
T
P
V
T
L
N
S
A
A
P
A
Site 117
S1026
N
T
P
V
T
L
N
S
A
A
P
A
S
N
S
Site 118
S1040
S
G
A
G
V
L
P
S
P
A
T
P
R
F
S
Site 119
S1047
S
P
A
T
P
R
F
S
V
P
T
P
R
T
P
Site 120
T1050
T
P
R
F
S
V
P
T
P
R
T
P
R
T
P
Site 121
T1053
F
S
V
P
T
P
R
T
P
R
T
P
R
T
P
Site 122
T1056
P
T
P
R
T
P
R
T
P
R
T
P
R
G
G
Site 123
T1059
R
T
P
R
T
P
R
T
P
R
G
G
G
T
A
Site 124
T1065
R
T
P
R
G
G
G
T
A
S
G
Q
G
S
V
Site 125
S1067
P
R
G
G
G
T
A
S
G
Q
G
S
V
K
Y
Site 126
S1071
G
T
A
S
G
Q
G
S
V
K
Y
D
S
T
D
Site 127
Y1074
S
G
Q
G
S
V
K
Y
D
S
T
D
Q
G
S
Site 128
S1076
Q
G
S
V
K
Y
D
S
T
D
Q
G
S
P
A
Site 129
T1077
G
S
V
K
Y
D
S
T
D
Q
G
S
P
A
S
Site 130
S1081
Y
D
S
T
D
Q
G
S
P
A
S
T
P
S
T
Site 131
S1084
T
D
Q
G
S
P
A
S
T
P
S
T
T
R
P
Site 132
T1085
D
Q
G
S
P
A
S
T
P
S
T
T
R
P
L
Site 133
S1087
G
S
P
A
S
T
P
S
T
T
R
P
L
N
S
Site 134
T1088
S
P
A
S
T
P
S
T
T
R
P
L
N
S
V
Site 135
S1094
S
T
T
R
P
L
N
S
V
E
P
A
T
M
Q
Site 136
T1099
L
N
S
V
E
P
A
T
M
Q
P
I
P
E
A
Site 137
Y1148
K
G
A
D
V
G
L
Y
I
P
D
S
S
N
E
Site 138
S1152
V
G
L
Y
I
P
D
S
S
N
E
D
Q
Y
R
Site 139
S1153
G
L
Y
I
P
D
S
S
N
E
D
Q
Y
R
C
Site 140
Y1158
D
S
S
N
E
D
Q
Y
R
C
T
C
G
F
S
Site 141
T1161
N
E
D
Q
Y
R
C
T
C
G
F
S
A
I
M
Site 142
S1165
Y
R
C
T
C
G
F
S
A
I
M
N
R
K
L
Site 143
S1224
K
P
Q
E
P
P
I
S
L
L
L
L
L
Q
N
Site 144
T1234
L
L
L
Q
N
Q
H
T
Q
P
F
A
S
L
N
Site 145
Y1245
A
S
L
N
F
L
D
Y
I
S
S
N
N
R
Q
Site 146
S1248
N
F
L
D
Y
I
S
S
N
N
R
Q
T
L
P
Site 147
T1253
I
S
S
N
N
R
Q
T
L
P
C
V
S
W
S
Site 148
Y1261
L
P
C
V
S
W
S
Y
D
R
V
Q
A
D
N
Site 149
Y1271
V
Q
A
D
N
N
D
Y
W
T
E
C
F
N
A
Site 150
Y1285
A
L
E
Q
G
R
Q
Y
V
D
N
P
T
G
G
Site 151
S1301
V
D
E
A
L
V
R
S
A
T
V
H
S
W
P
Site 152
T1303
E
A
L
V
R
S
A
T
V
H
S
W
P
H
S
Site 153
S1306
V
R
S
A
T
V
H
S
W
P
H
S
N
V
L
Site 154
S1316
H
S
N
V
L
D
I
S
M
L
S
S
Q
D
V
Site 155
S1320
L
D
I
S
M
L
S
S
Q
D
V
V
R
M
L
Site 156
T1370
H
K
M
A
G
R
G
T
Y
G
S
E
E
S
P
Site 157
Y1371
K
M
A
G
R
G
T
Y
G
S
E
E
S
P
E
Site 158
S1373
A
G
R
G
T
Y
G
S
E
E
S
P
E
P
L
Site 159
S1376
G
T
Y
G
S
E
E
S
P
E
P
L
P
I
P
Site 160
T1395
G
Y
D
K
D
F
L
T
I
S
P
F
S
L
P
Site 161
Y1412
E
R
L
L
L
D
P
Y
G
G
H
R
D
V
A
Site 162
Y1420
G
G
H
R
D
V
A
Y
I
V
V
C
P
E
N
Site 163
S1442
K
T
F
F
R
D
L
S
A
V
Y
E
M
C
R
Site 164
Y1445
F
R
D
L
S
A
V
Y
E
M
C
R
L
G
Q
Site 165
T1470
G
I
M
R
V
G
K
T
V
A
Q
K
L
T
D
Site 166
Y1502
N
H
S
R
L
K
L
Y
A
Q
V
C
R
H
H
Site 167
Y1513
C
R
H
H
L
A
P
Y
L
A
T
L
Q
L
D
Site 168
S1521
L
A
T
L
Q
L
D
S
S
L
L
I
P
P
K
Site 169
S1522
A
T
L
Q
L
D
S
S
L
L
I
P
P
K
Y
Site 170
Y1529
S
L
L
I
P
P
K
Y
Q
T
P
P
A
A
A
Site 171
T1531
L
I
P
P
K
Y
Q
T
P
P
A
A
A
Q
G
Site 172
T1541
A
A
A
Q
G
Q
A
T
P
G
N
A
G
P
L
Site 173
S1553
G
P
L
A
P
N
G
S
A
A
P
P
A
G
S
Site 174
S1560
S
A
A
P
P
A
G
S
A
F
N
P
T
S
N
Site 175
T1565
A
G
S
A
F
N
P
T
S
N
S
S
S
T
N
Site 176
S1566
G
S
A
F
N
P
T
S
N
S
S
S
T
N
P
Site 177
S1568
A
F
N
P
T
S
N
S
S
S
T
N
P
A
A
Site 178
S1570
N
P
T
S
N
S
S
S
T
N
P
A
A
S
S
Site 179
T1571
P
T
S
N
S
S
S
T
N
P
A
A
S
S
S
Site 180
S1576
S
S
T
N
P
A
A
S
S
S
A
S
G
S
S
Site 181
S1577
S
T
N
P
A
A
S
S
S
A
S
G
S
S
V
Site 182
S1578
T
N
P
A
A
S
S
S
A
S
G
S
S
V
P
Site 183
S1580
P
A
A
S
S
S
A
S
G
S
S
V
P
P
V
Site 184
S1582
A
S
S
S
A
S
G
S
S
V
P
P
V
S
S
Site 185
S1583
S
S
S
A
S
G
S
S
V
P
P
V
S
S
S
Site 186
S1588
G
S
S
V
P
P
V
S
S
S
A
S
A
P
G
Site 187
S1592
P
P
V
S
S
S
A
S
A
P
G
I
S
Q
I
Site 188
S1597
S
A
S
A
P
G
I
S
Q
I
S
T
T
S
S
Site 189
S1600
A
P
G
I
S
Q
I
S
T
T
S
S
S
G
F
Site 190
T1601
P
G
I
S
Q
I
S
T
T
S
S
S
G
F
S
Site 191
T1602
G
I
S
Q
I
S
T
T
S
S
S
G
F
S
G
Site 192
S1603
I
S
Q
I
S
T
T
S
S
S
G
F
S
G
S
Site 193
S1604
S
Q
I
S
T
T
S
S
S
G
F
S
G
S
V
Site 194
S1605
Q
I
S
T
T
S
S
S
G
F
S
G
S
V
G
Site 195
S1608
T
T
S
S
S
G
F
S
G
S
V
G
G
Q
N
Site 196
S1610
S
S
S
G
F
S
G
S
V
G
G
Q
N
P
S
Site 197
S1617
S
V
G
G
Q
N
P
S
T
G
G
I
S
A
D
Site 198
T1618
V
G
G
Q
N
P
S
T
G
G
I
S
A
D
R
Site 199
T1626
G
G
I
S
A
D
R
T
Q
G
N
I
G
C
G
Site 200
T1636
N
I
G
C
G
G
D
T
D
P
G
Q
S
S
S
Site 201
S1641
G
D
T
D
P
G
Q
S
S
S
Q
P
S
Q
D
Site 202
S1642
D
T
D
P
G
Q
S
S
S
Q
P
S
Q
D
G
Site 203
S1643
T
D
P
G
Q
S
S
S
Q
P
S
Q
D
G
Q
Site 204
S1646
G
Q
S
S
S
Q
P
S
Q
D
G
Q
E
S
V
Site 205
S1652
P
S
Q
D
G
Q
E
S
V
T
E
R
E
R
I
Site 206
T1654
Q
D
G
Q
E
S
V
T
E
R
E
R
I
G
I
Site 207
T1663
R
E
R
I
G
I
P
T
E
P
D
S
A
D
S
Site 208
S1667
G
I
P
T
E
P
D
S
A
D
S
H
A
H
P
Site 209
S1670
T
E
P
D
S
A
D
S
H
A
H
P
P
A
V
Site 210
T1686
I
Y
M
V
D
P
F
T
Y
A
A
E
E
D
S
Site 211
T1694
Y
A
A
E
E
D
S
T
S
G
N
F
W
L
L
Site 212
S1695
A
A
E
E
D
S
T
S
G
N
F
W
L
L
S
Site 213
Y1743
M
K
D
E
Q
V
F
Y
I
Q
Y
L
K
S
M
Site 214
T1764
Q
C
R
R
P
L
P
T
Q
I
H
I
K
S
L
Site 215
S1770
P
T
Q
I
H
I
K
S
L
T
G
F
G
P
A
Site 216
S1779
T
G
F
G
P
A
A
S
I
E
M
T
L
K
N
Site 217
T1783
P
A
A
S
I
E
M
T
L
K
N
P
E
R
P
Site 218
S1791
L
K
N
P
E
R
P
S
P
I
Q
L
Y
S
P
Site 219
T1810
A
P
I
K
D
K
Q
T
E
L
G
E
T
F
G
Site 220
T1815
K
Q
T
E
L
G
E
T
F
G
E
A
S
Q
K
Site 221
S1820
G
E
T
F
G
E
A
S
Q
K
Y
N
V
L
F
Site 222
Y1823
F
G
E
A
S
Q
K
Y
N
V
L
F
V
G
Y
Site 223
S1842
D
Q
R
W
L
L
A
S
C
T
D
L
H
G
E
Site 224
S1864
N
I
A
L
P
N
R
S
R
R
S
K
V
S
A
Site 225
S1867
L
P
N
R
S
R
R
S
K
V
S
A
R
K
I
Site 226
S1870
R
S
R
R
S
K
V
S
A
R
K
I
G
L
Q
Site 227
S1913
H
G
E
L
K
D
W
S
I
L
L
G
E
C
S
Site 228
T1923
L
G
E
C
S
L
Q
T
I
S
K
K
L
K
D
Site 229
T1976
G
S
V
F
G
R
S
T
A
L
N
M
Q
S
S
Site 230
S1983
T
A
L
N
M
Q
S
S
Q
L
N
T
P
Q
D
Site 231
T1987
M
Q
S
S
Q
L
N
T
P
Q
D
A
S
C
T
Site 232
Y2012
I
Q
V
A
P
A
N
Y
P
N
E
D
G
F
S
Site 233
S2019
Y
P
N
E
D
G
F
S
P
N
N
D
D
M
F
Site 234
S2049
L
M
T
G
N
L
H
S
S
P
N
S
S
P
V
Site 235
S2050
M
T
G
N
L
H
S
S
P
N
S
S
P
V
P
Site 236
S2053
N
L
H
S
S
P
N
S
S
P
V
P
S
P
G
Site 237
S2054
L
H
S
S
P
N
S
S
P
V
P
S
P
G
S
Site 238
S2058
P
N
S
S
P
V
P
S
P
G
S
P
S
G
I
Site 239
S2061
S
P
V
P
S
P
G
S
P
S
G
I
G
V
G
Site 240
S2063
V
P
S
P
G
S
P
S
G
I
G
V
G
S
H
Site 241
S2069
P
S
G
I
G
V
G
S
H
F
Q
H
S
R
S
Site 242
S2074
V
G
S
H
F
Q
H
S
R
S
Q
G
E
R
L
Site 243
S2076
S
H
F
Q
H
S
R
S
Q
G
E
R
L
L
S
Site 244
S2083
S
Q
G
E
R
L
L
S
R
E
A
P
E
E
L
Site 245
S2137
A
S
L
H
H
H
I
S
V
A
Q
T
D
E
L
Site 246
T2141
H
H
I
S
V
A
Q
T
D
E
L
L
P
A
R
Site 247
S2150
E
L
L
P
A
R
N
S
Q
R
V
P
H
P
L
Site 248
S2159
R
V
P
H
P
L
D
S
K
T
T
S
D
V
L
Site 249
T2161
P
H
P
L
D
S
K
T
T
S
D
V
L
R
F
Site 250
T2189
N
P
A
T
Q
D
R
T
S
C
L
P
V
H
F
Site 251
S2190
P
A
T
Q
D
R
T
S
C
L
P
V
H
F
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation