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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM5C
Full Name:
Protein FAM5C
Alias:
DBCCR1-like protein 1
Type:
Mass (Da):
88445
Number AA:
766
UniProt ID:
Q76B58
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S42
V
S
D
Q
H
A
T
S
P
F
D
W
L
L
S
Site 2
S49
S
P
F
D
W
L
L
S
D
K
G
P
F
H
R
Site 3
S57
D
K
G
P
F
H
R
S
Q
E
Y
T
D
F
V
Site 4
T61
F
H
R
S
Q
E
Y
T
D
F
V
D
R
S
R
Site 5
S67
Y
T
D
F
V
D
R
S
R
Q
G
F
S
T
R
Site 6
S72
D
R
S
R
Q
G
F
S
T
R
Y
K
I
Y
R
Site 7
T73
R
S
R
Q
G
F
S
T
R
Y
K
I
Y
R
E
Site 8
Y75
R
Q
G
F
S
T
R
Y
K
I
Y
R
E
F
G
Site 9
Y78
F
S
T
R
Y
K
I
Y
R
E
F
G
R
W
K
Site 10
S99
E
R
R
N
F
L
G
S
P
L
P
L
A
P
E
Site 11
T119
R
L
L
G
R
R
P
T
L
Q
Q
I
T
E
N
Site 12
Y131
T
E
N
L
I
K
K
Y
G
T
H
F
L
L
S
Site 13
S138
Y
G
T
H
F
L
L
S
A
T
L
G
G
E
E
Site 14
T140
T
H
F
L
L
S
A
T
L
G
G
E
E
S
L
Site 15
S146
A
T
L
G
G
E
E
S
L
T
I
F
V
D
K
Site 16
T148
L
G
G
E
E
S
L
T
I
F
V
D
K
R
K
Site 17
S157
F
V
D
K
R
K
L
S
K
R
A
E
G
S
D
Site 18
S163
L
S
K
R
A
E
G
S
D
S
T
T
N
S
S
Site 19
S165
K
R
A
E
G
S
D
S
T
T
N
S
S
S
V
Site 20
T166
R
A
E
G
S
D
S
T
T
N
S
S
S
V
T
Site 21
T167
A
E
G
S
D
S
T
T
N
S
S
S
V
T
L
Site 22
S169
G
S
D
S
T
T
N
S
S
S
V
T
L
E
T
Site 23
S171
D
S
T
T
N
S
S
S
V
T
L
E
T
L
H
Site 24
T173
T
T
N
S
S
S
V
T
L
E
T
L
H
Q
L
Site 25
Y184
L
H
Q
L
A
A
S
Y
F
I
D
R
D
S
T
Site 26
S190
S
Y
F
I
D
R
D
S
T
L
R
R
L
H
H
Site 27
T191
Y
F
I
D
R
D
S
T
L
R
R
L
H
H
I
Site 28
S218
R
T
G
P
L
G
C
S
N
Y
D
N
L
D
S
Site 29
Y220
G
P
L
G
C
S
N
Y
D
N
L
D
S
V
S
Site 30
S225
S
N
Y
D
N
L
D
S
V
S
S
V
L
V
Q
Site 31
S227
Y
D
N
L
D
S
V
S
S
V
L
V
Q
S
P
Site 32
S228
D
N
L
D
S
V
S
S
V
L
V
Q
S
P
E
Site 33
S233
V
S
S
V
L
V
Q
S
P
E
N
K
I
Q
L
Site 34
T307
E
E
N
L
L
R
I
T
E
T
W
K
A
Y
N
Site 35
Y313
I
T
E
T
W
K
A
Y
N
S
D
F
E
E
S
Site 36
S315
E
T
W
K
A
Y
N
S
D
F
E
E
S
D
E
Site 37
S320
Y
N
S
D
F
E
E
S
D
E
F
K
L
F
M
Site 38
Y334
M
K
R
L
P
M
N
Y
F
L
N
T
S
T
I
Site 39
Y355
D
S
N
F
Q
R
R
Y
E
Q
L
E
N
S
M
Site 40
S378
K
I
V
H
K
L
F
S
L
S
K
R
C
H
K
Site 41
S380
V
H
K
L
F
S
L
S
K
R
C
H
K
Q
P
Site 42
S390
C
H
K
Q
P
L
I
S
L
P
R
Q
R
T
S
Site 43
T396
I
S
L
P
R
Q
R
T
S
T
Y
W
L
T
R
Site 44
S397
S
L
P
R
Q
R
T
S
T
Y
W
L
T
R
I
Site 45
T398
L
P
R
Q
R
T
S
T
Y
W
L
T
R
I
Q
Site 46
T402
R
T
S
T
Y
W
L
T
R
I
Q
S
F
L
Y
Site 47
Y409
T
R
I
Q
S
F
L
Y
C
N
E
N
G
L
L
Site 48
S418
N
E
N
G
L
L
G
S
F
S
E
E
T
H
S
Site 49
S420
N
G
L
L
G
S
F
S
E
E
T
H
S
C
T
Site 50
S425
S
F
S
E
E
T
H
S
C
T
C
P
N
D
Q
Site 51
T451
G
D
A
S
A
C
L
T
C
A
P
D
N
R
T
Site 52
T462
D
N
R
T
R
C
G
T
C
N
T
G
Y
M
L
Site 53
Y485
V
A
E
S
T
D
H
Y
I
G
F
E
T
D
L
Site 54
Y499
L
Q
D
L
E
M
K
Y
L
L
Q
K
T
D
R
Site 55
T504
M
K
Y
L
L
Q
K
T
D
R
R
I
E
V
H
Site 56
T536
W
R
K
R
M
L
L
T
L
K
S
N
K
Y
K
Site 57
S539
R
M
L
L
T
L
K
S
N
K
Y
K
S
S
L
Site 58
Y542
L
T
L
K
S
N
K
Y
K
S
S
L
V
H
M
Site 59
S544
L
K
S
N
K
Y
K
S
S
L
V
H
M
I
L
Site 60
S545
K
S
N
K
Y
K
S
S
L
V
H
M
I
L
G
Site 61
S581
N
P
F
G
G
S
H
S
E
S
W
F
M
P
V
Site 62
Y628
F
F
E
T
V
H
I
Y
L
R
S
R
I
K
S
Site 63
S631
T
V
H
I
Y
L
R
S
R
I
K
S
N
G
P
Site 64
S635
Y
L
R
S
R
I
K
S
N
G
P
N
G
N
E
Site 65
S643
N
G
P
N
G
N
E
S
I
Y
Y
E
P
L
E
Site 66
Y645
P
N
G
N
E
S
I
Y
Y
E
P
L
E
F
I
Site 67
Y646
N
G
N
E
S
I
Y
Y
E
P
L
E
F
I
D
Site 68
S655
P
L
E
F
I
D
P
S
R
N
L
G
Y
M
K
Site 69
Y660
D
P
S
R
N
L
G
Y
M
K
I
N
N
I
Q
Site 70
Y689
D
L
I
L
Q
L
D
Y
P
Y
T
Q
G
S
Q
Site 71
Y691
I
L
Q
L
D
Y
P
Y
T
Q
G
S
Q
D
S
Site 72
T692
L
Q
L
D
Y
P
Y
T
Q
G
S
Q
D
S
A
Site 73
S695
D
Y
P
Y
T
Q
G
S
Q
D
S
A
L
L
Q
Site 74
S714
R
D
R
V
N
K
L
S
P
P
G
Q
R
R
L
Site 75
S725
Q
R
R
L
D
L
F
S
C
L
L
R
H
R
L
Site 76
S735
L
R
H
R
L
K
L
S
T
S
E
V
V
R
I
Site 77
T736
R
H
R
L
K
L
S
T
S
E
V
V
R
I
Q
Site 78
S737
H
R
L
K
L
S
T
S
E
V
V
R
I
Q
S
Site 79
Y759
K
L
P
N
T
M
D
Y
D
T
T
K
L
C
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation