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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RUFY3
Full Name:
Protein RUFY3
Alias:
KIAA0871; Rap2-interacting protein x; RIPX; RUN and FYVE domain containing 3; Singar1; Single axon-regulated protein; Single axon-related 1
Type:
Mass (Da):
52946
Number AA:
469
UniProt ID:
Q7L099
International Prot ID:
IPI00033573
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030175
GO:0030426
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0050771
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
A
L
T
P
P
T
D
Site 2
T5
_
_
_
M
S
A
L
T
P
P
T
D
M
P
T
Site 3
T8
M
S
A
L
T
P
P
T
D
M
P
T
P
T
T
Site 4
T12
T
P
P
T
D
M
P
T
P
T
T
D
K
I
T
Site 5
S34
Y
L
C
K
F
R
V
S
M
D
G
E
W
L
C
Site 6
S49
L
R
E
L
D
D
I
S
L
T
P
D
P
E
P
Site 7
T51
E
L
D
D
I
S
L
T
P
D
P
E
P
T
H
Site 8
Y63
P
T
H
E
D
P
N
Y
L
M
A
N
E
R
M
Site 9
T93
S
A
L
N
L
G
R
T
L
D
S
D
Y
A
P
Site 10
S96
N
L
G
R
T
L
D
S
D
Y
A
P
L
Q
Q
Site 11
Y98
G
R
T
L
D
S
D
Y
A
P
L
Q
Q
F
F
Site 12
T121
H
G
L
K
A
K
K
T
F
L
G
Q
N
K
S
Site 13
S128
T
F
L
G
Q
N
K
S
F
W
G
P
L
E
L
Site 14
T158
K
D
L
P
G
L
K
T
P
V
G
R
G
R
A
Site 15
S177
A
L
M
Q
K
K
L
S
E
Y
M
K
A
L
I
Site 16
Y194
K
E
L
L
S
E
F
Y
E
P
N
A
L
M
M
Site 17
S231
M
K
G
E
D
L
D
S
Q
V
G
V
I
D
F
Site 18
Y241
G
V
I
D
F
S
M
Y
L
K
D
G
N
S
S
Site 19
S247
M
Y
L
K
D
G
N
S
S
K
G
T
E
G
D
Site 20
T251
D
G
N
S
S
K
G
T
E
G
D
G
Q
I
T
Site 21
Y266
A
I
L
D
Q
K
N
Y
V
E
E
L
N
R
H
Site 22
T277
L
N
R
H
L
N
A
T
V
N
N
L
Q
A
K
Site 23
S291
K
V
D
A
L
E
K
S
N
T
K
L
T
E
E
Site 24
T293
D
A
L
E
K
S
N
T
K
L
T
E
E
L
A
Site 25
T308
V
A
N
N
R
I
I
T
L
Q
E
E
M
E
R
Site 26
S320
M
E
R
V
K
E
E
S
S
Y
I
L
E
S
N
Site 27
S321
E
R
V
K
E
E
S
S
Y
I
L
E
S
N
R
Site 28
Y322
R
V
K
E
E
S
S
Y
I
L
E
S
N
R
K
Site 29
S326
E
S
S
Y
I
L
E
S
N
R
K
G
P
K
Q
Site 30
T336
K
G
P
K
Q
D
R
T
A
E
G
Q
A
L
S
Site 31
S343
T
A
E
G
Q
A
L
S
E
A
R
K
H
L
K
Site 32
S368
K
E
L
E
M
Q
I
S
M
R
Q
E
M
E
L
Site 33
S393
E
K
Q
D
A
L
V
S
L
R
Q
Q
L
D
D
Site 34
S415
L
A
F
K
L
Q
S
S
D
L
G
V
K
Q
K
Site 35
S423
D
L
G
V
K
Q
K
S
E
L
N
S
R
L
E
Site 36
S427
K
Q
K
S
E
L
N
S
R
L
E
E
K
T
N
Site 37
T433
N
S
R
L
E
E
K
T
N
Q
M
A
A
T
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation