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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SV2A
Full Name:
Synaptic vesicle glycoprotein 2A
Alias:
KIAA0736; SV2
Type:
Vesicle protein
Mass (Da):
82695
Number AA:
742
UniProt ID:
Q7L0J3
International Prot ID:
IPI00644025
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0005783
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005215
PhosphoSite+
KinaseNET
Biological Process:
GO:0006836
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y41
L
D
R
V
Q
D
E
Y
S
R
R
S
Y
S
R
Site 2
S42
D
R
V
Q
D
E
Y
S
R
R
S
Y
S
R
F
Site 3
S45
Q
D
E
Y
S
R
R
S
Y
S
R
F
E
E
E
Site 4
Y46
D
E
Y
S
R
R
S
Y
S
R
F
E
E
E
D
Site 5
S47
E
Y
S
R
R
S
Y
S
R
F
E
E
E
D
D
Site 6
S62
D
D
D
F
P
A
P
S
D
G
Y
Y
R
G
E
Site 7
Y65
F
P
A
P
S
D
G
Y
Y
R
G
E
G
T
Q
Site 8
Y66
P
A
P
S
D
G
Y
Y
R
G
E
G
T
Q
D
Site 9
S80
D
E
E
E
G
G
A
S
S
D
A
T
E
G
H
Site 10
S81
E
E
E
G
G
A
S
S
D
A
T
E
G
H
D
Site 11
T84
G
G
A
S
S
D
A
T
E
G
H
D
E
D
D
Site 12
Y94
H
D
E
D
D
E
I
Y
E
G
E
Y
Q
G
I
Site 13
Y98
D
E
I
Y
E
G
E
Y
Q
G
I
P
R
A
E
Site 14
S106
Q
G
I
P
R
A
E
S
G
G
K
G
E
R
M
Site 15
S127
A
G
V
R
G
G
L
S
D
G
E
G
P
P
G
Site 16
S200
A
E
K
D
M
C
L
S
D
S
N
K
G
M
L
Site 17
S202
K
D
M
C
L
S
D
S
N
K
G
M
L
G
L
Site 18
Y328
S
F
Q
M
G
S
A
Y
Q
F
H
S
W
R
V
Site 19
T353
F
A
I
G
A
L
T
T
Q
P
E
S
P
R
F
Site 20
S357
A
L
T
T
Q
P
E
S
P
R
F
F
L
E
N
Site 21
S393
G
H
P
E
R
V
F
S
V
T
H
I
K
T
I
Site 22
T395
P
E
R
V
F
S
V
T
H
I
K
T
I
H
Q
Site 23
Y417
Q
S
D
T
G
T
W
Y
Q
R
W
G
V
R
A
Site 24
S426
R
W
G
V
R
A
L
S
L
G
G
Q
V
W
G
Site 25
Y480
R
H
L
Q
A
V
D
Y
A
S
R
T
K
V
F
Site 26
S482
L
Q
A
V
D
Y
A
S
R
T
K
V
F
P
G
Site 27
T496
G
E
R
V
E
H
V
T
F
N
F
T
L
E
N
Site 28
Y511
Q
I
H
R
G
G
Q
Y
F
N
D
K
F
I
G
Site 29
S525
G
L
R
L
K
S
V
S
F
E
D
S
L
F
E
Site 30
S529
K
S
V
S
F
E
D
S
L
F
E
E
C
Y
F
Site 31
Y535
D
S
L
F
E
E
C
Y
F
E
D
V
T
S
S
Site 32
T544
E
D
V
T
S
S
N
T
F
F
R
N
C
T
F
Site 33
Y564
Y
N
T
D
L
F
E
Y
K
F
V
N
S
R
L
Site 34
T575
N
S
R
L
I
N
S
T
F
L
H
N
K
E
G
Site 35
T588
E
G
C
P
L
D
V
T
G
T
G
E
G
A
Y
Site 36
Y677
D
V
L
T
V
E
L
Y
P
S
D
K
R
T
T
Site 37
S679
L
T
V
E
L
Y
P
S
D
K
R
T
T
A
F
Site 38
T683
L
Y
P
S
D
K
R
T
T
A
F
G
F
L
N
Site 39
T684
Y
P
S
D
K
R
T
T
A
F
G
F
L
N
A
Site 40
T736
L
A
L
K
L
P
E
T
R
G
Q
V
L
Q
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation