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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DPPA4
Full Name:
Developmental pluripotency-associated protein 4
Alias:
developmental pluripotency associated 4; developmental pluripotency-associated 4; FLJ10713
Type:
Cell pluripotentiality protein
Mass (Da):
33527
Number AA:
304
UniProt ID:
Q7L190
International Prot ID:
IPI00018878
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
L
R
G
S
A
S
S
T
S
M
E
Site 2
S7
_
M
L
R
G
S
A
S
S
T
S
M
E
K
A
Site 3
S8
M
L
R
G
S
A
S
S
T
S
M
E
K
A
K
Site 4
T9
L
R
G
S
A
S
S
T
S
M
E
K
A
K
G
Site 5
S10
R
G
S
A
S
S
T
S
M
E
K
A
K
G
K
Site 6
S21
A
K
G
K
E
W
T
S
T
E
K
S
R
E
E
Site 7
T22
K
G
K
E
W
T
S
T
E
K
S
R
E
E
D
Site 8
S25
E
W
T
S
T
E
K
S
R
E
E
D
Q
Q
A
Site 9
S33
R
E
E
D
Q
Q
A
S
N
Q
P
N
S
I
A
Site 10
S38
Q
A
S
N
Q
P
N
S
I
A
L
P
G
T
S
Site 11
T49
P
G
T
S
A
K
R
T
K
E
K
M
S
V
K
Site 12
S54
K
R
T
K
E
K
M
S
V
K
G
S
K
V
L
Site 13
S58
E
K
M
S
V
K
G
S
K
V
L
C
P
K
K
Site 14
T70
P
K
K
K
A
E
H
T
D
N
P
R
P
Q
K
Site 15
Y118
K
G
Q
K
L
D
A
Y
K
R
L
C
A
F
A
Site 16
Y126
K
R
L
C
A
F
A
Y
P
N
Q
K
D
F
P
Site 17
S144
K
E
A
K
I
R
K
S
L
Q
K
K
L
K
V
Site 18
T156
L
K
V
E
K
G
E
T
S
L
Q
S
S
E
T
Site 19
S157
K
V
E
K
G
E
T
S
L
Q
S
S
E
T
H
Site 20
S160
K
G
E
T
S
L
Q
S
S
E
T
H
P
P
E
Site 21
S161
G
E
T
S
L
Q
S
S
E
T
H
P
P
E
V
Site 22
T163
T
S
L
Q
S
S
E
T
H
P
P
E
V
A
L
Site 23
S210
L
A
S
W
A
R
I
S
A
R
A
R
T
P
E
Site 24
T215
R
I
S
A
R
A
R
T
P
E
A
V
E
S
P
Site 25
S221
R
T
P
E
A
V
E
S
P
Q
E
A
S
G
V
Site 26
S226
V
E
S
P
Q
E
A
S
G
V
R
W
C
V
V
Site 27
S237
W
C
V
V
H
G
K
S
L
P
A
D
T
D
G
Site 28
S266
E
K
Q
E
G
R
V
S
A
L
F
L
L
P
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation