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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SV2B
Full Name:
Synaptic vesicle glycoprotein 2B
Alias:
Type:
Vesicle protein
Mass (Da):
77444
Number AA:
683
UniProt ID:
Q7L1I2
International Prot ID:
IPI00006631
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0001669
GO:0030054
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005215
PhosphoSite+
KinaseNET
Biological Process:
GO:0006836
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y6
_
_
M
D
D
Y
K
Y
Q
D
N
Y
G
G
Y
Site 2
Y10
D
Y
K
Y
Q
D
N
Y
G
G
Y
A
P
S
D
Site 3
Y13
Y
Q
D
N
Y
G
G
Y
A
P
S
D
G
Y
Y
Site 4
Y19
G
Y
A
P
S
D
G
Y
Y
R
G
N
E
S
N
Site 5
Y20
Y
A
P
S
D
G
Y
Y
R
G
N
E
S
N
P
Site 6
S25
G
Y
Y
R
G
N
E
S
N
P
E
E
D
A
Q
Site 7
S33
N
P
E
E
D
A
Q
S
D
V
T
E
G
H
D
Site 8
Y46
H
D
E
E
D
E
I
Y
E
G
E
Y
Q
G
I
Site 9
S69
K
Q
A
K
M
A
P
S
R
M
D
S
L
R
G
Site 10
S73
M
A
P
S
R
M
D
S
L
R
G
Q
T
D
L
Site 11
T78
M
D
S
L
R
G
Q
T
D
L
M
A
E
R
L
Site 12
S143
A
E
K
D
M
C
L
S
S
S
K
K
G
M
L
Site 13
S145
K
D
M
C
L
S
S
S
K
K
G
M
L
G
M
Site 14
S228
A
Y
F
S
E
F
L
S
R
E
K
R
G
E
H
Site 15
T330
T
N
M
R
A
K
G
T
P
E
K
V
F
T
V
Site 16
T336
G
T
P
E
K
V
F
T
V
S
N
I
K
T
P
Site 17
S338
P
E
K
V
F
T
V
S
N
I
K
T
P
K
Q
Site 18
T342
F
T
V
S
N
I
K
T
P
K
Q
M
D
E
F
Site 19
Y360
Q
S
S
T
G
T
W
Y
Q
R
W
L
V
R
F
Site 20
Y380
Q
V
W
D
N
A
L
Y
C
V
M
G
P
Y
R
Site 21
Y417
W
F
P
D
M
I
R
Y
F
Q
D
E
E
Y
K
Site 22
Y423
R
Y
F
Q
D
E
E
Y
K
S
K
M
K
V
F
Site 23
Y463
N
D
K
F
T
R
M
Y
F
K
H
V
L
F
E
Site 24
Y478
D
T
F
F
D
E
C
Y
F
E
D
V
T
S
T
Site 25
T483
E
C
Y
F
E
D
V
T
S
T
D
T
Y
F
K
Site 26
Y488
D
V
T
S
T
D
T
Y
F
K
N
C
T
I
E
Site 27
Y500
T
I
E
S
T
I
F
Y
N
T
D
L
Y
E
H
Site 28
Y505
I
F
Y
N
T
D
L
Y
E
H
K
F
I
N
C
Site 29
T518
N
C
R
F
I
N
S
T
F
L
E
Q
K
E
G
Site 30
Y618
D
V
I
T
V
E
L
Y
P
T
N
Q
R
A
T
Site 31
T620
I
T
V
E
L
Y
P
T
N
Q
R
A
T
A
F
Site 32
T625
Y
P
T
N
Q
R
A
T
A
F
G
I
L
N
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation