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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DHX30
Full Name:
Putative ATP-dependent RNA helicase DHX30
Alias:
ATP-dependent RNA helicase DHX30; DDX30; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 30; DEAH (Asp-Glu-Ala-His) box polypeptide 30; DEAH box protein 30; FLJ11214; KIAA0890
Type:
Helicase; EC 3.6.1.-
Mass (Da):
133938
Number AA:
1194
UniProt ID:
Q7L2E3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0042645
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0008026
GO:0003723
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
F
S
L
D
S
F
R
K
D
R
A
Q
Site 2
T34
P
P
M
C
V
N
P
T
P
G
G
T
I
S
R
Site 3
T38
V
N
P
T
P
G
G
T
I
S
R
A
S
R
D
Site 4
S40
P
T
P
G
G
T
I
S
R
A
S
R
D
L
L
Site 5
S43
G
G
T
I
S
R
A
S
R
D
L
L
K
E
F
Site 6
S59
Q
P
K
N
L
L
N
S
V
I
G
R
A
L
G
Site 7
Y76
H
A
K
D
K
L
V
Y
V
H
T
N
G
P
K
Site 8
S96
L
H
I
K
W
P
K
S
V
E
V
E
G
Y
G
Site 9
Y102
K
S
V
E
V
E
G
Y
G
S
K
K
I
D
A
Site 10
S148
V
L
A
D
R
F
G
S
P
A
D
S
W
W
R
Site 11
S152
R
F
G
S
P
A
D
S
W
W
R
P
E
P
T
Site 12
T163
P
E
P
T
M
P
P
T
S
W
R
Q
L
N
P
Site 13
S164
E
P
T
M
P
P
T
S
W
R
Q
L
N
P
E
Site 14
S172
W
R
Q
L
N
P
E
S
I
R
P
G
G
P
G
Site 15
S182
P
G
G
P
G
G
L
S
R
S
L
G
R
E
E
Site 16
S184
G
P
G
G
L
S
R
S
L
G
R
E
E
E
E
Site 17
T205
E
E
G
T
I
D
V
T
D
F
L
S
M
T
Q
Site 18
S209
I
D
V
T
D
F
L
S
M
T
Q
Q
D
S
H
Site 19
T211
V
T
D
F
L
S
M
T
Q
Q
D
S
H
A
P
Site 20
S215
L
S
M
T
Q
Q
D
S
H
A
P
L
R
D
S
Site 21
S222
S
H
A
P
L
R
D
S
R
G
S
S
F
E
M
Site 22
S225
P
L
R
D
S
R
G
S
S
F
E
M
T
D
D
Site 23
S226
L
R
D
S
R
G
S
S
F
E
M
T
D
D
D
Site 24
T230
R
G
S
S
F
E
M
T
D
D
D
S
A
I
R
Site 25
S234
F
E
M
T
D
D
D
S
A
I
R
A
L
T
Q
Site 26
T240
D
S
A
I
R
A
L
T
Q
F
P
L
P
K
N
Site 27
S260
I
Q
I
A
T
S
S
S
T
A
K
N
L
M
Q
Site 28
T270
K
N
L
M
Q
F
H
T
V
G
T
K
T
K
L
Site 29
S314
L
A
C
K
K
L
K
S
L
G
L
V
D
R
N
Site 30
T326
D
R
N
N
E
P
L
T
H
A
M
Y
N
L
A
Site 31
Y330
E
P
L
T
H
A
M
Y
N
L
A
S
L
R
E
Site 32
S334
H
A
M
Y
N
L
A
S
L
R
E
L
G
E
T
Site 33
T341
S
L
R
E
L
G
E
T
Q
R
R
P
C
T
I
Site 34
T347
E
T
Q
R
R
P
C
T
I
Q
V
P
E
P
I
Site 35
T360
P
I
L
R
K
I
E
T
F
L
N
H
Y
P
V
Site 36
Y365
I
E
T
F
L
N
H
Y
P
V
E
S
S
W
I
Site 37
S380
A
P
E
L
R
L
Q
S
D
D
I
L
P
L
G
Site 38
S394
G
K
D
S
G
P
L
S
D
P
I
T
G
K
P
Site 39
T398
G
P
L
S
D
P
I
T
G
K
P
Y
V
P
L
Site 40
Y402
D
P
I
T
G
K
P
Y
V
P
L
L
E
A
E
Site 41
S414
E
A
E
E
V
R
L
S
Q
S
L
L
E
L
W
Site 42
S416
E
E
V
R
L
S
Q
S
L
L
E
L
W
R
R
Site 43
T442
P
V
D
P
H
R
D
T
I
L
N
A
I
E
Q
Site 44
S456
Q
H
P
V
V
V
I
S
G
D
T
G
C
G
K
Site 45
T464
G
D
T
G
C
G
K
T
T
R
I
P
Q
L
L
Site 46
T465
D
T
G
C
G
K
T
T
R
I
P
Q
L
L
L
Site 47
Y475
P
Q
L
L
L
E
R
Y
V
T
E
G
R
G
A
Site 48
T477
L
L
L
E
R
Y
V
T
E
G
R
G
A
R
C
Site 49
T489
A
R
C
N
V
I
I
T
Q
P
R
R
I
S
A
Site 50
S495
I
T
Q
P
R
R
I
S
A
V
S
V
A
Q
R
Site 51
S498
P
R
R
I
S
A
V
S
V
A
Q
R
V
S
H
Site 52
S504
V
S
V
A
Q
R
V
S
H
E
L
G
P
S
L
Site 53
S510
V
S
H
E
L
G
P
S
L
R
R
N
V
G
F
Site 54
S523
G
F
Q
V
R
L
E
S
K
P
P
S
R
G
G
Site 55
S527
R
L
E
S
K
P
P
S
R
G
G
A
L
L
F
Site 56
S546
I
L
L
R
K
L
Q
S
N
P
S
L
E
G
V
Site 57
S549
R
K
L
Q
S
N
P
S
L
E
G
V
S
H
V
Site 58
S591
A
L
R
L
V
L
M
S
A
T
G
D
N
E
R
Site 59
S600
T
G
D
N
E
R
F
S
R
Y
F
G
G
C
P
Site 60
Y602
D
N
E
R
F
S
R
Y
F
G
G
C
P
V
I
Site 61
Y622
M
Y
P
V
K
E
H
Y
L
E
D
I
L
A
K
Site 62
Y635
A
K
L
G
K
H
Q
Y
L
H
R
H
R
H
H
Site 63
S644
H
R
H
R
H
H
E
S
E
D
E
C
A
L
D
Site 64
S749
D
I
V
H
V
V
D
S
G
L
H
K
E
E
R
Site 65
T761
E
E
R
Y
D
L
K
T
K
V
S
C
L
E
T
Site 66
T768
T
K
V
S
C
L
E
T
V
W
V
S
R
A
N
Site 67
S788
G
R
A
G
R
C
Q
S
G
F
A
Y
H
L
F
Site 68
Y792
R
C
Q
S
G
F
A
Y
H
L
F
P
R
S
R
Site 69
S798
A
Y
H
L
F
P
R
S
R
L
E
K
M
V
P
Site 70
T831
K
I
H
M
P
E
K
T
A
V
E
F
L
S
K
Site 71
S837
K
T
A
V
E
F
L
S
K
A
V
D
S
P
N
Site 72
S842
F
L
S
K
A
V
D
S
P
N
I
K
A
V
D
Site 73
Y866
G
V
L
D
Q
R
E
Y
L
T
T
L
G
Q
R
Site 74
T869
D
Q
R
E
Y
L
T
T
L
G
Q
R
L
A
H
Site 75
S878
G
Q
R
L
A
H
I
S
T
D
P
R
L
A
K
Site 76
T879
Q
R
L
A
H
I
S
T
D
P
R
L
A
K
A
Site 77
S912
C
L
T
R
D
P
F
S
S
S
L
Q
N
R
A
Site 78
S913
L
T
R
D
P
F
S
S
S
L
Q
N
R
A
E
Site 79
S914
T
R
D
P
F
S
S
S
L
Q
N
R
A
E
V
Site 80
S929
D
K
V
K
A
L
L
S
H
D
S
G
S
D
H
Site 81
S932
K
A
L
L
S
H
D
S
G
S
D
H
L
A
F
Site 82
S934
L
L
S
H
D
S
G
S
D
H
L
A
F
V
R
Site 83
S956
V
L
R
W
Q
D
R
S
S
R
E
N
Y
L
E
Site 84
S957
L
R
W
Q
D
R
S
S
R
E
N
Y
L
E
E
Site 85
Y961
D
R
S
S
R
E
N
Y
L
E
E
N
L
L
Y
Site 86
Y968
Y
L
E
E
N
L
L
Y
A
P
S
L
R
F
I
Site 87
Y987
K
Q
F
S
E
N
I
Y
E
A
F
L
V
G
K
Site 88
T999
V
G
K
P
S
D
C
T
L
A
S
A
Q
C
N
Site 89
S1002
P
S
D
C
T
L
A
S
A
Q
C
N
E
Y
S
Site 90
S1009
S
A
Q
C
N
E
Y
S
E
E
E
E
L
V
K
Site 91
T1036
Q
V
R
Q
G
K
V
T
R
Q
G
K
F
K
P
Site 92
S1045
Q
G
K
F
K
P
N
S
V
T
Y
R
T
K
S
Site 93
T1047
K
F
K
P
N
S
V
T
Y
R
T
K
S
G
N
Site 94
Y1048
F
K
P
N
S
V
T
Y
R
T
K
S
G
N
I
Site 95
S1052
S
V
T
Y
R
T
K
S
G
N
I
L
L
H
K
Site 96
S1060
G
N
I
L
L
H
K
S
T
I
N
R
E
A
T
Site 97
T1061
N
I
L
L
H
K
S
T
I
N
R
E
A
T
R
Site 98
T1067
S
T
I
N
R
E
A
T
R
L
R
S
R
W
L
Site 99
S1071
R
E
A
T
R
L
R
S
R
W
L
T
Y
F
M
Site 100
T1075
R
L
R
S
R
W
L
T
Y
F
M
A
V
K
S
Site 101
Y1076
L
R
S
R
W
L
T
Y
F
M
A
V
K
S
N
Site 102
S1082
T
Y
F
M
A
V
K
S
N
G
S
V
F
V
R
Site 103
S1085
M
A
V
K
S
N
G
S
V
F
V
R
D
S
S
Site 104
S1091
G
S
V
F
V
R
D
S
S
Q
V
H
P
L
A
Site 105
S1092
S
V
F
V
R
D
S
S
Q
V
H
P
L
A
V
Site 106
T1103
P
L
A
V
L
L
L
T
D
G
D
V
H
I
R
Site 107
T1117
R
D
D
G
R
R
A
T
I
S
L
S
D
S
D
Site 108
S1119
D
G
R
R
A
T
I
S
L
S
D
S
D
L
L
Site 109
S1121
R
R
A
T
I
S
L
S
D
S
D
L
L
R
L
Site 110
S1132
L
L
R
L
E
G
D
S
R
T
V
R
L
L
K
Site 111
T1134
R
L
E
G
D
S
R
T
V
R
L
L
K
E
L
Site 112
S1152
L
G
R
M
V
E
R
S
L
R
S
E
L
A
A
Site 113
S1163
E
L
A
A
L
P
P
S
V
Q
E
E
H
G
Q
Site 114
S1185
L
L
R
G
P
C
G
S
F
D
V
R
K
T
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation