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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EIF3M
Full Name:
Eukaryotic translation initiation factor 3 subunit M
Alias:
Fetal lung protein B5;PCI domain-containing protein 1
Type:
Receptor
Mass (Da):
42503
Number AA:
374
UniProt ID:
Q7L2H7
International Prot ID:
IPI00102069
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005852
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0003743
PhosphoSite+
KinaseNET
Biological Process:
GO:0006413
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
V
P
A
F
I
D
I
Site 2
Y21
Q
A
A
E
L
R
A
Y
L
K
S
K
G
A
E
Site 3
S24
E
L
R
A
Y
L
K
S
K
G
A
E
I
S
E
Site 4
S30
K
S
K
G
A
E
I
S
E
E
N
S
E
G
G
Site 5
S34
A
E
I
S
E
E
N
S
E
G
G
L
H
V
D
Site 6
S62
E
D
D
K
D
V
E
S
V
M
N
S
V
V
S
Site 7
S85
K
Q
E
A
L
I
E
S
L
C
E
K
L
V
K
Site 8
S100
F
R
E
G
E
R
P
S
L
R
L
Q
L
L
S
Site 9
T117
F
H
G
M
D
K
N
T
P
V
R
Y
T
V
Y
Site 10
T122
K
N
T
P
V
R
Y
T
V
Y
C
S
L
I
K
Site 11
T163
L
T
T
E
K
K
H
T
L
L
R
L
L
Y
E
Site 12
S178
A
L
V
D
C
K
K
S
D
A
A
S
K
V
M
Site 13
S191
V
M
V
E
L
L
G
S
Y
T
E
D
N
A
S
Site 14
T193
V
E
L
L
G
S
Y
T
E
D
N
A
S
Q
A
Site 15
S198
S
Y
T
E
D
N
A
S
Q
A
R
V
D
A
H
Site 16
Y252
V
S
A
K
L
A
S
Y
V
K
F
Y
Q
N
N
Site 17
T281
M
A
K
M
R
L
L
T
F
M
G
M
A
V
E
Site 18
S293
A
V
E
N
K
E
I
S
F
D
T
M
Q
Q
E
Site 19
Y322
A
V
R
T
K
M
V
Y
C
K
I
D
Q
T
Q
Site 20
T328
V
Y
C
K
I
D
Q
T
Q
R
K
V
V
V
S
Site 21
S335
T
Q
R
K
V
V
V
S
H
S
T
H
R
T
F
Site 22
S337
R
K
V
V
V
S
H
S
T
H
R
T
F
G
K
Site 23
T338
K
V
V
V
S
H
S
T
H
R
T
F
G
K
Q
Site 24
T341
V
S
H
S
T
H
R
T
F
G
K
Q
Q
W
Q
Site 25
Y351
K
Q
Q
W
Q
Q
L
Y
D
T
L
N
A
W
K
Site 26
T353
Q
W
Q
Q
L
Y
D
T
L
N
A
W
K
Q
N
Site 27
S367
N
L
N
K
V
K
N
S
L
L
S
L
S
D
T
Site 28
S370
K
V
K
N
S
L
L
S
L
S
D
T
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation