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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SH3BP5L
Full Name:
SH3 domain-binding protein 5-like
Alias:
3BP5L; KIAA1720; SH3-binding domain 5-like; SH3-binding domain protein 5-like
Type:
Mass (Da):
43499
Number AA:
393
UniProt ID:
Q7L8J4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T13
Q
V
P
G
G
R
E
T
P
Q
G
E
L
R
P
Site 2
S30
V
E
D
E
V
P
R
S
P
V
A
E
E
P
G
Site 3
S42
E
P
G
G
G
G
S
S
S
S
E
A
K
L
S
Site 4
S43
P
G
G
G
G
S
S
S
S
E
A
K
L
S
P
Site 5
S44
G
G
G
G
S
S
S
S
E
A
K
L
S
P
R
Site 6
S49
S
S
S
E
A
K
L
S
P
R
E
E
E
E
L
Site 7
T87
Q
L
D
E
A
R
T
T
Y
R
R
I
L
Q
E
Site 8
Y88
L
D
E
A
R
T
T
Y
R
R
I
L
Q
E
S
Site 9
S95
Y
R
R
I
L
Q
E
S
A
R
K
L
N
T
Q
Site 10
T101
E
S
A
R
K
L
N
T
Q
G
S
H
L
G
S
Site 11
S104
R
K
L
N
T
Q
G
S
H
L
G
S
C
I
E
Site 12
S108
T
Q
G
S
H
L
G
S
C
I
E
K
A
R
P
Site 13
Y116
C
I
E
K
A
R
P
Y
Y
E
A
R
R
L
A
Site 14
Y117
I
E
K
A
R
P
Y
Y
E
A
R
R
L
A
K
Site 15
Y137
T
Q
K
A
A
L
R
Y
E
R
A
V
S
M
H
Site 16
S142
L
R
Y
E
R
A
V
S
M
H
N
A
A
R
E
Site 17
T198
E
R
E
H
Q
R
V
T
R
L
C
Q
Q
A
E
Site 18
T214
R
V
Q
A
L
Q
K
T
L
R
R
A
I
G
K
Site 19
S222
L
R
R
A
I
G
K
S
R
P
Y
F
E
L
K
Site 20
Y225
A
I
G
K
S
R
P
Y
F
E
L
K
A
Q
F
Site 21
S233
F
E
L
K
A
Q
F
S
Q
I
L
E
E
H
K
Site 22
S258
A
Q
A
K
T
R
Y
S
V
A
L
R
N
L
E
Site 23
S289
H
P
L
G
P
R
R
S
S
P
V
G
A
E
A
Site 24
S290
P
L
G
P
R
R
S
S
P
V
G
A
E
A
G
Site 25
S306
E
D
M
E
D
G
D
S
G
I
E
G
A
E
G
Site 26
S321
A
G
L
E
E
G
S
S
L
G
P
G
P
A
P
Site 27
T330
G
P
G
P
A
P
D
T
D
T
L
S
L
L
S
Site 28
T332
G
P
A
P
D
T
D
T
L
S
L
L
S
L
R
Site 29
T340
L
S
L
L
S
L
R
T
V
A
S
D
L
Q
K
Site 30
S343
L
S
L
R
T
V
A
S
D
L
Q
K
C
D
S
Site 31
S350
S
D
L
Q
K
C
D
S
V
E
H
L
R
G
L
Site 32
S358
V
E
H
L
R
G
L
S
D
H
V
S
L
D
G
Site 33
S362
R
G
L
S
D
H
V
S
L
D
G
Q
E
L
G
Site 34
S372
G
Q
E
L
G
T
R
S
G
G
R
R
G
S
D
Site 35
S378
R
S
G
G
R
R
G
S
D
G
G
A
R
G
G
Site 36
S390
R
G
G
R
H
Q
R
S
V
S
L
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation