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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FASTKD5
Full Name:
FAST kinase domain-containing protein 5
Alias:
FAKD5; FLJ13149
Type:
Mass (Da):
86574
Number AA:
764
UniProt ID:
Q7L8L6
International Prot ID:
IPI00414973
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004672
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y13
K
S
L
K
L
V
R
Y
R
A
F
C
S
P
S
Site 2
S29
F
G
A
V
R
S
V
S
Y
W
N
V
S
S
T
Site 3
Y30
G
A
V
R
S
V
S
Y
W
N
V
S
S
T
Q
Site 4
S34
S
V
S
Y
W
N
V
S
S
T
Q
H
G
G
Q
Site 5
S48
Q
D
P
P
E
H
I
S
L
C
H
S
A
K
K
Site 6
S52
E
H
I
S
L
C
H
S
A
K
K
V
K
N
I
Site 7
S61
K
K
V
K
N
I
C
S
T
F
S
S
R
R
I
Site 8
T62
K
V
K
N
I
C
S
T
F
S
S
R
R
I
L
Site 9
S64
K
N
I
C
S
T
F
S
S
R
R
I
L
T
T
Site 10
S65
N
I
C
S
T
F
S
S
R
R
I
L
T
T
S
Site 11
T70
F
S
S
R
R
I
L
T
T
S
S
A
H
P
G
Site 12
T71
S
S
R
R
I
L
T
T
S
S
A
H
P
G
L
Site 13
S72
S
R
R
I
L
T
T
S
S
A
H
P
G
L
E
Site 14
S73
R
R
I
L
T
T
S
S
A
H
P
G
L
E
F
Site 15
S81
A
H
P
G
L
E
F
S
K
T
S
S
S
K
A
Site 16
T83
P
G
L
E
F
S
K
T
S
S
S
K
A
S
T
Site 17
S84
G
L
E
F
S
K
T
S
S
S
K
A
S
T
L
Site 18
S85
L
E
F
S
K
T
S
S
S
K
A
S
T
L
Q
Site 19
S86
E
F
S
K
T
S
S
S
K
A
S
T
L
Q
L
Site 20
S89
K
T
S
S
S
K
A
S
T
L
Q
L
G
S
P
Site 21
T90
T
S
S
S
K
A
S
T
L
Q
L
G
S
P
R
Site 22
S95
A
S
T
L
Q
L
G
S
P
R
A
T
G
V
D
Site 23
T99
Q
L
G
S
P
R
A
T
G
V
D
E
E
D
V
Site 24
S111
E
D
V
E
V
F
D
S
F
E
N
M
R
V
F
Site 25
Y125
F
L
Q
L
R
P
E
Y
R
V
H
S
Y
N
A
Site 26
S129
R
P
E
Y
R
V
H
S
Y
N
A
S
E
T
S
Site 27
Y130
P
E
Y
R
V
H
S
Y
N
A
S
E
T
S
Q
Site 28
S133
R
V
H
S
Y
N
A
S
E
T
S
Q
L
L
S
Site 29
S136
S
Y
N
A
S
E
T
S
Q
L
L
S
V
S
E
Site 30
S140
S
E
T
S
Q
L
L
S
V
S
E
G
E
L
I
Site 31
S171
V
D
Y
L
C
K
L
S
S
L
P
A
E
Q
H
Site 32
S172
D
Y
L
C
K
L
S
S
L
P
A
E
Q
H
P
Site 33
S223
L
G
I
P
H
S
H
S
M
L
D
V
Y
E
T
Site 34
Y228
S
H
S
M
L
D
V
Y
E
T
K
C
C
H
Q
Site 35
Y253
L
V
A
D
L
W
R
Y
L
G
R
K
V
P
R
Site 36
S277
N
L
H
W
K
D
L
S
L
S
Q
L
V
H
L
Site 37
Y286
S
Q
L
V
H
L
I
Y
V
I
G
E
N
R
Q
Site 38
S295
I
G
E
N
R
Q
V
S
Q
D
L
M
Q
K
L
Site 39
S333
F
K
S
S
T
N
L
S
E
F
V
M
R
K
I
Site 40
T439
K
I
L
W
S
F
G
T
L
N
Y
K
P
P
N
Site 41
Y442
W
S
F
G
T
L
N
Y
K
P
P
N
A
E
E
Site 42
Y451
P
P
N
A
E
E
F
Y
S
S
L
I
S
E
I
Site 43
S452
P
N
A
E
E
F
Y
S
S
L
I
S
E
I
H
Site 44
S453
N
A
E
E
F
Y
S
S
L
I
S
E
I
H
R
Site 45
S456
E
F
Y
S
S
L
I
S
E
I
H
R
K
M
P
Site 46
Y468
K
M
P
E
F
N
Q
Y
P
E
H
L
P
T
C
Site 47
T520
E
L
Y
T
L
D
G
T
V
G
I
E
C
P
D
Site 48
Y528
V
G
I
E
C
P
D
Y
R
G
N
R
L
S
T
Site 49
S534
D
Y
R
G
N
R
L
S
T
H
L
Q
Q
E
G
Site 50
T535
Y
R
G
N
R
L
S
T
H
L
Q
Q
E
G
S
Site 51
Y547
E
G
S
E
L
L
W
Y
L
A
E
K
D
M
N
Site 52
S555
L
A
E
K
D
M
N
S
K
P
E
F
L
E
T
Site 53
T585
H
H
M
I
L
P
H
T
R
S
S
D
L
E
V
Site 54
S587
M
I
L
P
H
T
R
S
S
D
L
E
V
Q
L
Site 55
S588
I
L
P
H
T
R
S
S
D
L
E
V
Q
L
D
Site 56
T608
L
P
F
N
R
E
A
T
P
A
E
N
V
A
K
Site 57
S624
R
L
E
H
V
G
V
S
L
T
D
D
L
M
N
Site 58
T646
R
G
H
F
Q
G
K
T
E
S
E
P
G
Q
Q
Site 59
S648
H
F
Q
G
K
T
E
S
E
P
G
Q
Q
P
M
Site 60
Y707
Q
F
T
N
R
N
Q
Y
C
Y
G
S
R
D
L
Site 61
Y709
T
N
R
N
Q
Y
C
Y
G
S
R
D
L
L
G
Site 62
S711
R
N
Q
Y
C
Y
G
S
R
D
L
L
G
L
H
Site 63
Y730
R
Q
L
A
R
L
G
Y
R
V
V
E
L
S
Y
Site 64
T761
F
L
H
E
K
V
F
T
S
A
L
_
_
_
_
Site 65
S762
L
H
E
K
V
F
T
S
A
L
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation