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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
OTOP1
Full Name:
Otopetrin-1
Alias:
Type:
Mass (Da):
67353
Number AA:
612
UniProt ID:
Q7RTM1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
L
E
G
L
G
S
P
A
S
P
R
A
A
Site 2
S10
E
G
L
G
S
P
A
S
P
R
A
A
A
S
A
Site 3
S16
A
S
P
R
A
A
A
S
A
S
V
A
G
S
S
Site 4
S18
P
R
A
A
A
S
A
S
V
A
G
S
S
G
P
Site 5
S29
S
S
G
P
A
A
C
S
P
P
S
S
S
A
P
Site 6
S32
P
A
A
C
S
P
P
S
S
S
A
P
R
S
P
Site 7
S33
A
A
C
S
P
P
S
S
S
A
P
R
S
P
E
Site 8
S34
A
C
S
P
P
S
S
S
A
P
R
S
P
E
S
Site 9
S38
P
S
S
S
A
P
R
S
P
E
S
P
A
P
R
Site 10
S41
S
A
P
R
S
P
E
S
P
A
P
R
R
G
G
Site 11
S52
R
R
G
G
V
R
A
S
V
P
Q
K
L
A
E
Site 12
S115
L
W
Y
V
G
R
S
S
A
H
R
R
L
F
R
Site 13
T126
R
L
F
R
L
K
D
T
H
A
G
A
G
W
L
Site 14
S194
H
A
K
D
I
I
Q
S
F
K
T
L
E
R
F
Site 15
T235
E
H
K
E
R
L
I
T
L
G
F
G
N
I
T
Site 16
T249
T
T
V
L
D
D
H
T
P
Q
C
N
C
T
P
Site 17
T255
H
T
P
Q
C
N
C
T
P
P
T
L
C
T
A
Site 18
Y271
S
H
G
I
Y
Y
L
Y
P
F
N
I
E
Y
Q
Site 19
S339
Y
L
I
H
I
G
R
S
K
T
K
S
E
S
A
Site 20
T341
I
H
I
G
R
S
K
T
K
S
E
S
A
L
I
Site 21
S343
I
G
R
S
K
T
K
S
E
S
A
L
I
M
F
Site 22
Y372
G
L
A
G
I
R
I
Y
R
I
D
E
K
S
L
Site 23
S378
I
Y
R
I
D
E
K
S
L
D
E
S
K
N
P
Site 24
S382
D
E
K
S
L
D
E
S
K
N
P
A
R
K
L
Site 25
S391
N
P
A
R
K
L
D
S
D
L
L
V
G
T
A
Site 26
Y421
C
A
E
G
H
P
R
Y
T
W
Y
N
L
P
Y
Site 27
Y424
G
H
P
R
Y
T
W
Y
N
L
P
Y
S
I
L
Site 28
S446
Q
N
L
F
I
F
E
S
I
H
R
E
P
E
K
Site 29
S455
H
R
E
P
E
K
L
S
E
D
I
Q
T
L
R
Site 30
S476
G
N
T
M
P
L
A
S
S
C
P
K
S
G
G
Site 31
S477
N
T
M
P
L
A
S
S
C
P
K
S
G
G
V
Site 32
S481
L
A
S
S
C
P
K
S
G
G
V
A
R
D
V
Site 33
S508
G
N
V
C
M
R
E
S
H
D
K
E
E
E
K
Site 34
S519
E
E
E
K
Q
E
E
S
S
W
G
G
S
P
S
Site 35
S520
E
E
K
Q
E
E
S
S
W
G
G
S
P
S
P
Site 36
S524
E
E
S
S
W
G
G
S
P
S
P
V
R
L
P
Site 37
S526
S
S
W
G
G
S
P
S
P
V
R
L
P
R
F
Site 38
Y569
A
F
G
C
R
P
E
Y
D
N
G
L
E
E
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation