PhosphoNET

           
Protein Info 
   
Short Name:  STLK5
Full Name:  STE20-related kinase adapter protein alpha
Alias:  LYK5; Serologically defined breast cancer antigen NY-BR-96; STE20-related adapter protein; STRAD alpha
Type:  Protein kinase, Ser/Thr (non-receptor)
Mass (Da):  48369
Number AA:  431
UniProt ID:  Q7RTN6
International Prot ID:  Isoform1 - IPI00300700
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005634   Uniprot OncoNet
Molecular Function:  GO:0005524  GO:0005515  GO:0004672 PhosphoSite+ KinaseNET
Biological Process:  GO:0032147  GO:0007049  GO:0006468 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S6__MSFLVSKPERIRR
Site 2S16ERIRRWVSEKFIVEG
Site 3T42PGDTRRKTNDASSES
Site 4S46RRKTNDASSESIASF
Site 5S47RKTNDASSESIASFS
Site 6S49TNDASSESIASFSKQ
Site 7S52ASSESIASFSKQEVM
Site 8S54SESIASFSKQEVMSS
Site 9S61SKQEVMSSFLPEGGC
Site 10T84KGFEDLMTVNLARYK
Site 11Y90MTVNLARYKPTGEYV
Site 12Y96RYKPTGEYVTVRRIN
Site 13T98KPTGEYVTVRRINLE
Site 14S122LQGELHVSKLFNHPN
Site 15Y191DYIHHMGYVHRSVKA
Site 16Y210ISVDGKVYLSGLRSN
Site 17S212VDGKVYLSGLRSNLS
Site 18S219SGLRSNLSMISHGQR
Site 19S245VKVLPWLSPEVLQQN
Site 20Y256LQQNLQGYDAKSDIY
Site 21S260LQGYDAKSDIYSVGI
Site 22S264DAKSDIYSVGITACE
Site 23T311TIPAEELTMSPSRSV
Site 24S313PAEELTMSPSRSVAN
Site 25S315EELTMSPSRSVANSG
Site 26S317LTMSPSRSVANSGLS
Site 27S321PSRSVANSGLSDSLT
Site 28S324SVANSGLSDSLTTST
Site 29S326ANSGLSDSLTTSTPR
Site 30T328SGLSDSLTTSTPRPS
Site 31T329GLSDSLTTSTPRPSN
Site 32S330LSDSLTTSTPRPSNG
Site 33T331SDSLTTSTPRPSNGD
Site 34S335TTSTPRPSNGDSPSH
Site 35S339PRPSNGDSPSHPYHR
Site 36S341PSNGDSPSHPYHRTF
Site 37Y344GDSPSHPYHRTFSPH
Site 38S369RNPDARPSASTLLNH
Site 39S371PDARPSASTLLNHSF
Site 40T372DARPSASTLLNHSFF
Site 41S377ASTLLNHSFFKQIKR
Site 42S387KQIKRRASEALPELL
Site 43T398PELLRPVTPITNFEG
Site 44T401LRPVTPITNFEGSQS
Site 45S406PITNFEGSQSQDHSG
Site 46S408TNFEGSQSQDHSGIF
Site 47S412GSQSQDHSGIFGLVT
Site 48T419SGIFGLVTNLEELEV
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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