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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NLRP9
Full Name:
NACHT, LRR and PYD domains-containing protein 9
Alias:
Nucleotide-binding oligomerization domain protein 6;PYRIN and NACHT-containing protein 12
Type:
Mass (Da):
113312
Number AA:
991
UniProt ID:
Q7RTR0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y14
S
D
F
G
L
L
W
Y
L
K
E
L
R
K
E
Site 2
Y63
A
K
L
L
D
K
H
Y
P
G
K
Q
A
W
E
Site 3
T86
I
N
R
K
D
L
W
T
K
A
Q
E
E
M
R
Site 4
Y139
Y
K
E
L
N
D
A
Y
T
A
A
A
R
R
H
Site 5
T140
K
E
L
N
D
A
Y
T
A
A
A
R
R
H
T
Site 6
T147
T
A
A
A
R
R
H
T
V
V
L
E
G
P
D
Site 7
S203
T
S
L
L
E
L
L
S
R
D
W
P
E
S
S
Site 8
S209
L
S
R
D
W
P
E
S
S
E
K
I
E
D
I
Site 9
S210
S
R
D
W
P
E
S
S
E
K
I
E
D
I
F
Site 10
S218
E
K
I
E
D
I
F
S
Q
P
E
R
I
L
F
Site 11
S244
L
Q
L
K
A
D
L
S
D
D
W
R
Q
R
Q
Site 12
Y284
K
L
A
M
Q
K
H
Y
F
M
L
R
H
P
K
Site 13
S301
K
L
L
G
F
S
E
S
E
K
K
S
Y
F
S
Site 14
S305
F
S
E
S
E
K
K
S
Y
F
S
Y
F
F
G
Site 15
Y306
S
E
S
E
K
K
S
Y
F
S
Y
F
F
G
E
Site 16
Y309
E
K
K
S
Y
F
S
Y
F
F
G
E
K
S
K
Site 17
S315
S
Y
F
F
G
E
K
S
K
A
L
K
V
F
N
Site 18
S361
G
E
D
L
E
I
N
S
Q
N
T
T
Y
L
Y
Site 19
T365
E
I
N
S
Q
N
T
T
Y
L
Y
A
S
F
L
Site 20
Y366
I
N
S
Q
N
T
T
Y
L
Y
A
S
F
L
T
Site 21
S380
T
T
V
F
K
A
G
S
Q
S
F
P
P
K
V
Site 22
S382
V
F
K
A
G
S
Q
S
F
P
P
K
V
N
R
Site 23
S421
D
L
R
R
N
G
L
S
E
S
E
G
V
M
W
Site 24
S423
R
R
N
G
L
S
E
S
E
G
V
M
W
V
G
Site 25
Y457
E
F
C
A
A
M
F
Y
L
L
K
R
P
K
D
Site 26
S516
T
S
F
G
F
P
L
S
K
D
L
K
Q
E
I
Site 27
T524
K
D
L
K
Q
E
I
T
Q
C
L
E
S
L
S
Site 28
S529
E
I
T
Q
C
L
E
S
L
S
Q
C
E
A
D
Site 29
S531
T
Q
C
L
E
S
L
S
Q
C
E
A
D
R
E
Site 30
S610
P
D
D
S
G
C
I
S
D
Y
N
E
K
L
V
Site 31
Y612
D
S
G
C
I
S
D
Y
N
E
K
L
V
Y
W
Site 32
Y618
D
Y
N
E
K
L
V
Y
W
R
E
L
C
S
M
Site 33
S641
I
L
D
M
E
N
T
S
L
D
D
P
S
L
A
Site 34
T667
K
L
R
K
L
I
F
T
S
V
Y
F
G
H
D
Site 35
S691
N
P
H
L
K
L
L
S
L
Y
G
T
S
L
S
Site 36
Y693
H
L
K
L
L
S
L
Y
G
T
S
L
S
Q
S
Site 37
T695
K
L
L
S
L
Y
G
T
S
L
S
Q
S
D
I
Site 38
S696
L
L
S
L
Y
G
T
S
L
S
Q
S
D
I
R
Site 39
S698
S
L
Y
G
T
S
L
S
Q
S
D
I
R
H
L
Site 40
S700
Y
G
T
S
L
S
Q
S
D
I
R
H
L
C
E
Site 41
S748
N
S
K
L
K
H
L
S
L
V
E
N
P
L
R
Site 42
T760
P
L
R
D
E
G
M
T
L
L
C
E
A
L
K
Site 43
S808
L
S
L
L
D
L
G
S
N
A
L
E
D
N
G
Site 44
T871
G
H
N
E
I
G
D
T
G
V
R
Q
L
C
A
Site 45
S952
Q
M
L
G
L
H
K
S
G
F
D
E
E
T
Q
Site 46
T958
K
S
G
F
D
E
E
T
Q
K
I
L
M
S
V
Site 47
S964
E
T
Q
K
I
L
M
S
V
E
E
K
I
P
H
Site 48
T973
E
E
K
I
P
H
L
T
I
S
H
G
P
W
I
Site 49
Y984
G
P
W
I
D
E
E
Y
K
I
R
G
V
L
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation