PhosphoNET

           
Protein Info 
   
Short Name:  PTF1A
Full Name:  Pancreas transcription factor 1 subunit alpha
Alias:  Class A basic helix-loop-helix protein 29;Pancreas-specific transcription factor 1a;bHLH transcription factor p48;p48 DNA-binding subunit of transcription factor PTF1
Type: 
Mass (Da):  34970
Number AA:  328
UniProt ID:  Q7RTS3
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S18GGLDAFPSSYFDEDD
Site 2S19GLDAFPSSYFDEDDF
Site 3Y20LDAFPSSYFDEDDFF
Site 4T28FDEDDFFTDQSSRDP
Site 5S31DDFFTDQSSRDPLED
Site 6S32DFFTDQSSRDPLEDG
Site 7Y60LSHQLHEYCYRDGAC
Site 8S86LALAPPSSGGLGEPD
Site 9Y100DDGGGGGYCCETGAP
Site 10T104GGGYCCETGAPPGGF
Site 11Y113APPGGFPYSPGSPPS
Site 12S114PPGGFPYSPGSPPSC
Site 13S117GFPYSPGSPPSCLAY
Site 14S120YSPGSPPSCLAYPCA
Site 15S142GARLRGLSGAAAAAA
Site 16S157RRRRRVRSEAELQQL
Site 17S178RERRRMQSINDAFEG
Site 18S188DAFEGLRSHIPTLPY
Site 19T192GLRSHIPTLPYEKRL
Site 20Y195SHIPTLPYEKRLSKV
Site 21S200LPYEKRLSKVDTLRL
Site 22T204KRLSKVDTLRLAIGY
Site 23S246GGRLGGDSPGSQAQK
Site 24S249LGGDSPGSQAQKVII
Site 25T261VIICHRGTRSPSPSD
Site 26S263ICHRGTRSPSPSDPD
Site 27S265HRGTRSPSPSDPDYG
Site 28S267GTRSPSPSDPDYGLP
Site 29Y271PSPSDPDYGLPPLAG
Site 30S280LPPLAGHSLSWTDEK
Site 31S282PLAGHSLSWTDEKQL
Site 32T284AGHSLSWTDEKQLKE
Site 33T302IRTAKVWTPEDPRKL
Site 34S311EDPRKLNSKSSFNNI
Site 35S313PRKLNSKSSFNNIEN
Site 36S314RKLNSKSSFNNIENE
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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