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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
OTOP2
Full Name:
Otopetrin-2
Alias:
Type:
Mass (Da):
62236
Number AA:
562
UniProt ID:
Q7RTS6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
L
A
Q
G
P
K
E
S
P
P
A
P
R
A
G
Site 2
Y124
M
D
V
F
K
T
G
Y
Y
S
S
F
F
E
C
Site 3
Y125
D
V
F
K
T
G
Y
Y
S
S
F
F
E
C
Q
Site 4
S127
F
K
T
G
Y
Y
S
S
F
F
E
C
Q
S
A
Site 5
S192
M
A
A
V
V
D
E
S
V
H
Q
S
H
S
Y
Site 6
S196
V
D
E
S
V
H
Q
S
H
S
Y
S
S
S
H
Site 7
S198
E
S
V
H
Q
S
H
S
Y
S
S
S
H
S
N
Site 8
Y199
S
V
H
Q
S
H
S
Y
S
S
S
H
S
N
A
Site 9
S200
V
H
Q
S
H
S
Y
S
S
S
H
S
N
A
S
Site 10
S202
Q
S
H
S
Y
S
S
S
H
S
N
A
S
H
A
Site 11
S204
H
S
Y
S
S
S
H
S
N
A
S
H
A
R
L
Site 12
S207
S
S
S
H
S
N
A
S
H
A
R
L
I
S
D
Site 13
S213
A
S
H
A
R
L
I
S
D
E
H
A
D
N
P
Site 14
Y244
Q
Q
G
Y
F
Y
L
Y
P
F
N
I
E
Y
S
Site 15
S271
N
V
G
R
F
L
A
S
T
P
G
H
S
H
T
Site 16
T272
V
G
R
F
L
A
S
T
P
G
H
S
H
T
P
Site 17
S276
L
A
S
T
P
G
H
S
H
T
P
T
P
V
S
Site 18
T278
S
T
P
G
H
S
H
T
P
T
P
V
S
L
F
Site 19
T280
P
G
H
S
H
T
P
T
P
V
S
L
F
R
E
Site 20
S283
S
H
T
P
T
P
V
S
L
F
R
E
T
F
F
Site 21
S315
I
I
Y
E
V
Q
V
S
G
D
G
S
R
T
R
Site 22
S319
V
Q
V
S
G
D
G
S
R
T
R
Q
A
L
V
Site 23
T366
H
H
K
N
P
T
R
T
L
D
V
A
L
L
M
Site 24
S424
Q
N
M
F
I
I
E
S
L
H
R
G
P
P
G
Site 25
S436
P
P
G
A
E
P
H
S
T
H
P
K
E
P
C
Site 26
T437
P
G
A
E
P
H
S
T
H
P
K
E
P
C
Q
Site 27
T447
K
E
P
C
Q
D
L
T
F
T
N
L
D
A
L
Site 28
T449
P
C
Q
D
L
T
F
T
N
L
D
A
L
H
T
Site 29
T456
T
N
L
D
A
L
H
T
L
S
A
C
P
P
N
Site 30
S458
L
D
A
L
H
T
L
S
A
C
P
P
N
P
G
Site 31
S468
P
P
N
P
G
L
V
S
P
S
P
S
D
Q
R
Site 32
S470
N
P
G
L
V
S
P
S
P
S
D
Q
R
E
A
Site 33
S472
G
L
V
S
P
S
P
S
D
Q
R
E
A
V
A
Site 34
S482
R
E
A
V
A
I
V
S
T
P
R
S
Q
W
R
Site 35
T483
E
A
V
A
I
V
S
T
P
R
S
Q
W
R
R
Site 36
S486
A
I
V
S
T
P
R
S
Q
W
R
R
Q
C
L
Site 37
S520
F
G
A
R
P
H
F
S
N
T
V
E
V
D
F
Site 38
T522
A
R
P
H
F
S
N
T
V
E
V
D
F
Y
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation