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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DYM
Full Name:
Dymeclin
Alias:
DMC; FLJ20071; FLJ90130; SMC
Type:
Mass (Da):
75940
Number AA:
UniProt ID:
Q7RTS9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y16
G
D
L
P
K
N
E
Y
L
K
K
L
S
G
T
Site 2
S21
N
E
Y
L
K
K
L
S
G
T
E
S
I
S
E
Site 3
T23
Y
L
K
K
L
S
G
T
E
S
I
S
E
N
D
Site 4
S25
K
K
L
S
G
T
E
S
I
S
E
N
D
P
F
Site 5
S27
L
S
G
T
E
S
I
S
E
N
D
P
F
W
N
Site 6
S40
W
N
Q
L
L
S
F
S
F
P
A
P
T
S
S
Site 7
T45
S
F
S
F
P
A
P
T
S
S
S
E
L
K
L
Site 8
S47
S
F
P
A
P
T
S
S
S
E
L
K
L
L
E
Site 9
S48
F
P
A
P
T
S
S
S
E
L
K
L
L
E
E
Site 10
S63
A
T
I
S
V
C
R
S
L
V
E
N
N
P
R
Site 11
S91
R
T
K
E
L
K
L
S
A
E
C
Q
N
H
I
Site 12
S122
K
V
F
I
C
Q
M
S
E
E
E
L
Q
L
H
Site 13
T131
E
E
L
Q
L
H
F
T
Y
E
E
K
S
P
G
Site 14
Y132
E
L
Q
L
H
F
T
Y
E
E
K
S
P
G
N
Site 15
S136
H
F
T
Y
E
E
K
S
P
G
N
Y
S
S
D
Site 16
Y140
E
E
K
S
P
G
N
Y
S
S
D
S
E
D
L
Site 17
S141
E
K
S
P
G
N
Y
S
S
D
S
E
D
L
L
Site 18
S142
K
S
P
G
N
Y
S
S
D
S
E
D
L
L
E
Site 19
S144
P
G
N
Y
S
S
D
S
E
D
L
L
E
E
L
Site 20
S196
H
K
E
V
L
R
Q
S
I
S
H
K
Y
L
M
Site 21
S198
E
V
L
R
Q
S
I
S
H
K
Y
L
M
R
G
Site 22
Y201
R
Q
S
I
S
H
K
Y
L
M
R
G
P
C
L
Site 23
T211
R
G
P
C
L
P
Y
T
S
K
L
V
K
T
L
Site 24
Y220
K
L
V
K
T
L
L
Y
N
F
I
R
Q
E
K
Site 25
S240
A
H
V
F
P
Q
Q
S
D
G
G
G
L
L
Y
Site 26
S273
V
G
S
K
A
A
A
S
P
E
L
S
S
P
L
Site 27
S277
A
A
A
S
P
E
L
S
S
P
L
A
N
Q
S
Site 28
S278
A
A
S
P
E
L
S
S
P
L
A
N
Q
S
L
Site 29
S298
L
A
N
L
T
D
A
S
D
A
P
N
P
Y
R
Site 30
S310
P
Y
R
Q
A
I
M
S
F
K
N
T
Q
D
S
Site 31
T314
A
I
M
S
F
K
N
T
Q
D
S
S
P
F
P
Site 32
S317
S
F
K
N
T
Q
D
S
S
P
F
P
S
S
I
Site 33
S318
F
K
N
T
Q
D
S
S
P
F
P
S
S
I
P
Site 34
S322
Q
D
S
S
P
F
P
S
S
I
P
H
A
F
Q
Site 35
S323
D
S
S
P
F
P
S
S
I
P
H
A
F
Q
I
Site 36
Y336
Q
I
N
F
N
S
L
Y
T
A
L
C
E
Q
Q
Site 37
Y353
D
Q
A
T
L
L
L
Y
T
L
L
H
Q
N
S
Site 38
Y365
Q
N
S
N
I
R
T
Y
M
L
A
R
T
D
M
Site 39
Y384
L
P
I
L
E
I
L
Y
H
V
E
E
R
N
S
Site 40
S413
E
D
D
G
F
N
R
S
I
H
E
V
I
L
K
Site 41
T431
W
Y
S
E
R
V
L
T
E
I
S
L
G
S
L
Site 42
T446
L
I
L
V
V
I
R
T
I
Q
Y
N
M
T
R
Site 43
Y449
V
V
I
R
T
I
Q
Y
N
M
T
R
T
R
D
Site 44
T452
R
T
I
Q
Y
N
M
T
R
T
R
D
K
Y
L
Site 45
Y458
M
T
R
T
R
D
K
Y
L
H
T
N
C
L
A
Site 46
Y480
Q
F
R
S
L
H
Q
Y
A
A
Q
R
I
I
S
Site 47
S490
Q
R
I
I
S
L
F
S
L
L
S
K
K
H
N
Site 48
S506
V
L
E
Q
A
T
Q
S
L
R
G
S
L
S
S
Site 49
S510
A
T
Q
S
L
R
G
S
L
S
S
N
D
V
P
Site 50
S512
Q
S
L
R
G
S
L
S
S
N
D
V
P
L
P
Site 51
S513
S
L
R
G
S
L
S
S
N
D
V
P
L
P
D
Site 52
Y521
N
D
V
P
L
P
D
Y
A
Q
D
L
N
V
I
Site 53
Y559
N
L
V
Y
A
L
L
Y
K
R
D
L
F
E
Q
Site 54
T569
D
L
F
E
Q
F
R
T
H
P
S
F
Q
D
I
Site 55
Y629
F
P
E
L
K
F
K
Y
V
E
E
E
Q
P
E
Site 56
Y655
Y
N
S
A
V
G
L
Y
W
N
P
Q
D
I
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation