PhosphoNET

           
Protein Info 
   
Short Name:  TCF23
Full Name:  Transcription factor 23
Alias:  Class A basic helix-loop-helix protein 24
Type: 
Mass (Da):  23309
Number AA:  214
UniProt ID:  Q7RTU1
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T20PGVGHSQTQAKARLL
Site 2S35PGADRKRSRLSRTRQ
Site 3S38DRKRSRLSRTRQDPW
Site 4S56SWSNQRWSRATPGPR
Site 5T59NQRWSRATPGPRGTR
Site 6T65ATPGPRGTRAGGLAL
Site 7S75GGLALGRSEASPENA
Site 8S78ALGRSEASPENAARE
Site 9S87ENAARERSRVRTLRQ
Site 10T91RERSRVRTLRQAFLA
Site 11T110LPAVPPDTKLSKLDV
Site 12Y150PFLRGLRYLHPLKKW
Site 13S161LKKWPMRSRLYAGGL
Site 14Y164WPMRSRLYAGGLGYS
Site 15S171YAGGLGYSDLDSTTA
Site 16S175LGYSDLDSTTASTPS
Site 17T176GYSDLDSTTASTPSQ
Site 18T177YSDLDSTTASTPSQR
Site 19S179DLDSTTASTPSQRTR
Site 20T180LDSTTASTPSQRTRD
Site 21S182STTASTPSQRTRDAE
Site 22S192TRDAEVGSQVPGEAD
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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