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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
OTOA
Full Name:
Otoancorin
Alias:
Cancer/testis antigen 108; CT108; DFNB22; Otoancorin
Type:
Mass (Da):
128530
Number AA:
UniProt ID:
Q7RTW8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0031225
GO:0005578
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0007605
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
F
L
S
H
G
V
S
S
Y
T
V
P
N
S
R
Site 2
Y23
L
S
H
G
V
S
S
Y
T
V
P
N
S
R
Q
Site 3
T24
S
H
G
V
S
S
Y
T
V
P
N
S
R
Q
D
Site 4
S28
S
S
Y
T
V
P
N
S
R
Q
D
L
H
P
L
Site 5
T65
F
Q
S
S
H
V
W
T
D
D
L
S
H
R
V
Site 6
T84
N
S
R
N
V
A
F
T
I
P
S
L
Q
A
A
Site 7
T113
L
L
E
D
L
R
K
T
D
A
Q
Q
F
R
T
Site 8
S152
I
R
E
R
A
L
Q
S
P
G
V
N
R
S
L
Site 9
S187
L
G
K
V
L
R
G
S
S
G
S
F
L
Q
P
Site 10
S188
G
K
V
L
R
G
S
S
G
S
F
L
Q
P
D
Site 11
S190
V
L
R
G
S
S
G
S
F
L
Q
P
D
I
T
Site 12
T197
S
F
L
Q
P
D
I
T
E
R
L
P
R
D
L
Site 13
S213
E
D
A
F
K
N
L
S
A
V
F
K
D
L
Y
Site 14
Y220
S
A
V
F
K
D
L
Y
D
K
T
S
A
H
S
Site 15
T223
F
K
D
L
Y
D
K
T
S
A
H
S
Q
R
A
Site 16
S224
K
D
L
Y
D
K
T
S
A
H
S
Q
R
A
L
Site 17
S227
Y
D
K
T
S
A
H
S
Q
R
A
L
Y
S
W
Site 18
Y232
A
H
S
Q
R
A
L
Y
S
W
M
T
G
I
L
Site 19
T246
L
Q
T
S
S
N
A
T
D
D
S
A
S
W
V
Site 20
S249
S
S
N
A
T
D
D
S
A
S
W
V
S
A
E
Site 21
S251
N
A
T
D
D
S
A
S
W
V
S
A
E
H
L
Site 22
S269
G
R
Y
M
V
H
L
S
F
E
E
I
T
K
I
Site 23
S286
I
E
I
G
L
F
I
S
Y
D
N
A
T
K
Q
Site 24
Y298
T
K
Q
L
D
M
V
Y
D
I
T
P
E
L
A
Site 25
S313
Q
A
F
L
E
R
I
S
S
S
N
F
N
M
R
Site 26
S314
A
F
L
E
R
I
S
S
S
N
F
N
M
R
N
Site 27
S315
F
L
E
R
I
S
S
S
N
F
N
M
R
N
T
Site 28
T322
S
N
F
N
M
R
N
T
S
T
I
H
R
Q
A
Site 29
S418
L
T
Y
S
Q
L
E
S
L
S
P
E
A
V
H
Site 30
S420
Y
S
Q
L
E
S
L
S
P
E
A
V
H
G
A
Site 31
S457
L
A
H
E
K
V
L
S
F
Y
N
V
S
Q
M
Site 32
Y459
H
E
K
V
L
S
F
Y
N
V
S
Q
M
G
A
Site 33
S478
V
S
T
Q
A
F
C
S
M
K
R
K
D
I
S
Site 34
S485
S
M
K
R
K
D
I
S
Q
V
L
R
S
A
V
Site 35
S490
D
I
S
Q
V
L
R
S
A
V
S
Q
Y
V
S
Site 36
S493
Q
V
L
R
S
A
V
S
Q
Y
V
S
D
L
S
Site 37
Y495
L
R
S
A
V
S
Q
Y
V
S
D
L
S
P
A
Site 38
S497
S
A
V
S
Q
Y
V
S
D
L
S
P
A
Q
Q
Site 39
S500
S
Q
Y
V
S
D
L
S
P
A
Q
Q
Q
G
I
Site 40
S533
G
A
F
F
K
E
V
S
L
F
D
L
R
R
Q
Site 41
S556
K
D
K
E
L
G
R
S
Q
A
L
F
L
Y
E
Site 42
T568
L
Y
E
L
L
L
K
T
T
R
R
P
E
E
L
Site 43
T569
Y
E
L
L
L
K
T
T
R
R
P
E
E
L
L
Site 44
S577
R
R
P
E
E
L
L
S
A
G
Q
L
V
K
G
Site 45
Y624
V
N
C
L
A
W
K
Y
W
E
V
S
R
L
S
Site 46
Y644
L
A
A
L
P
A
R
Y
L
A
S
V
P
A
S
Site 47
S667
L
G
K
S
W
L
D
S
L
V
L
D
S
H
K
Site 48
S672
L
D
S
L
V
L
D
S
H
K
K
T
S
V
L
Site 49
T676
V
L
D
S
H
K
K
T
S
V
L
R
K
V
Q
Site 50
S677
L
D
S
H
K
K
T
S
V
L
R
K
V
Q
Q
Site 51
S689
V
Q
Q
C
L
D
D
S
I
A
D
E
Y
T
V
Site 52
Y694
D
D
S
I
A
D
E
Y
T
V
D
I
M
G
N
Site 53
T695
D
S
I
A
D
E
Y
T
V
D
I
M
G
N
L
Site 54
Y749
R
L
K
L
L
G
Q
Y
G
L
P
Q
H
W
T
Site 55
S791
E
I
L
L
Q
A
A
S
K
M
A
R
T
L
P
Site 56
S809
F
L
W
A
V
F
Q
S
V
R
N
S
S
D
K
Site 57
S813
V
F
Q
S
V
R
N
S
S
D
K
I
P
S
Y
Site 58
S814
F
Q
S
V
R
N
S
S
D
K
I
P
S
Y
D
Site 59
S819
N
S
S
D
K
I
P
S
Y
D
P
M
P
G
C
Site 60
Y820
S
S
D
K
I
P
S
Y
D
P
M
P
G
C
H
Site 61
T859
L
R
C
M
E
E
D
T
F
I
R
T
V
E
L
Site 62
T880
F
S
R
P
Q
L
M
T
L
K
E
K
A
I
Q
Site 63
S921
E
L
E
Q
L
D
L
S
S
I
D
T
V
A
S
Site 64
S928
S
S
I
D
T
V
A
S
L
S
W
Q
T
E
W
Site 65
T936
L
S
W
Q
T
E
W
T
P
G
Q
A
E
S
I
Site 66
Y947
A
E
S
I
L
Q
G
Y
L
D
D
S
G
Y
S
Site 67
S951
L
Q
G
Y
L
D
D
S
G
Y
S
I
Q
D
L
Site 68
Y953
G
Y
L
D
D
S
G
Y
S
I
Q
D
L
K
S
Site 69
S1023
D
P
T
E
W
T
S
S
V
L
Q
E
L
G
T
Site 70
Y1050
L
D
K
D
L
M
P
Y
F
Q
P
S
A
I
K
Site 71
S1074
L
S
A
E
Q
I
A
S
L
G
P
E
N
A
A
Site 72
S1092
H
A
Q
R
R
R
L
S
P
L
Q
L
Q
S
L
Site 73
S1098
L
S
P
L
Q
L
Q
S
L
Q
Q
A
L
D
G
Site 74
S1110
L
D
G
A
K
T
H
S
W
Q
D
A
P
A
S
Site 75
S1117
S
W
Q
D
A
P
A
S
A
G
P
T
R
T
S
Site 76
T1121
A
P
A
S
A
G
P
T
R
T
S
S
S
R
S
Site 77
S1124
S
A
G
P
T
R
T
S
S
S
R
S
P
A
G
Site 78
S1125
A
G
P
T
R
T
S
S
S
R
S
P
A
G
A
Site 79
S1126
G
P
T
R
T
S
S
S
R
S
P
A
G
A
L
Site 80
S1128
T
R
T
S
S
S
R
S
P
A
G
A
L
Q
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation