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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LRRC70
Full Name:
Leucine-rich repeat-containing protein 70
Alias:
Synleurin
Type:
Mass (Da):
70301
Number AA:
622
UniProt ID:
Q7Z2Q7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S52
N
C
R
N
L
G
L
S
S
I
P
K
N
F
P
Site 2
S73
Y
L
T
G
N
N
I
S
Y
I
N
E
S
E
L
Site 3
Y74
L
T
G
N
N
I
S
Y
I
N
E
S
E
L
T
Site 4
S78
N
I
S
Y
I
N
E
S
E
L
T
G
L
H
S
Site 5
Y138
L
L
N
L
R
N
L
Y
L
Q
Y
N
Q
V
S
Site 6
Y141
L
R
N
L
Y
L
Q
Y
N
Q
V
S
F
V
P
Site 7
Y160
N
D
L
V
S
V
Q
Y
L
N
L
Q
R
N
R
Site 8
T169
N
L
Q
R
N
R
L
T
V
L
G
S
G
T
F
Site 9
S188
A
L
R
I
L
D
L
S
N
N
N
I
L
R
I
Site 10
S196
N
N
N
I
L
R
I
S
E
S
G
F
Q
H
L
Site 11
S198
N
I
L
R
I
S
E
S
G
F
Q
H
L
E
N
Site 12
T217
Y
L
G
S
N
N
L
T
K
V
P
S
N
A
F
Site 13
S221
N
N
L
T
K
V
P
S
N
A
F
E
V
L
K
Site 14
S229
N
A
F
E
V
L
K
S
L
R
R
L
S
L
S
Site 15
S234
L
K
S
L
R
R
L
S
L
S
H
N
P
I
E
Site 16
S236
S
L
R
R
L
S
L
S
H
N
P
I
E
A
I
Site 17
Y256
K
G
L
A
N
L
E
Y
L
L
L
K
N
S
R
Site 18
S262
E
Y
L
L
L
K
N
S
R
I
R
N
V
T
R
Site 19
T268
N
S
R
I
R
N
V
T
R
D
G
F
S
G
I
Site 20
S284
N
L
K
H
L
I
L
S
H
N
D
L
E
N
L
Site 21
S293
N
D
L
E
N
L
N
S
D
T
F
S
L
L
K
Site 22
T295
L
E
N
L
N
S
D
T
F
S
L
L
K
N
L
Site 23
S297
N
L
N
S
D
T
F
S
L
L
K
N
L
I
Y
Site 24
Y304
S
L
L
K
N
L
I
Y
L
K
L
D
R
N
R
Site 25
S314
L
D
R
N
R
I
I
S
I
D
N
D
T
F
E
Site 26
T319
I
I
S
I
D
N
D
T
F
E
N
M
G
A
S
Site 27
Y384
S
A
I
T
L
N
I
Y
C
Q
N
P
P
S
M
Site 28
S390
I
Y
C
Q
N
P
P
S
M
R
G
R
A
L
R
Site 29
T438
M
M
A
W
H
K
V
T
T
N
G
S
P
L
E
Site 30
S442
H
K
V
T
T
N
G
S
P
L
E
N
T
E
T
Site 31
T449
S
P
L
E
N
T
E
T
E
N
I
T
F
W
E
Site 32
T460
T
F
W
E
R
I
P
T
S
P
A
G
R
F
F
Site 33
S461
F
W
E
R
I
P
T
S
P
A
G
R
F
F
Q
Site 34
S508
A
L
P
N
D
A
A
S
M
S
G
K
T
S
L
Site 35
S510
P
N
D
A
A
S
M
S
G
K
T
S
L
I
C
Site 36
T518
G
K
T
S
L
I
C
T
Q
E
V
E
K
L
N
Site 37
S559
F
K
Q
K
L
K
A
S
E
N
S
R
E
N
R
Site 38
Y569
S
R
E
N
R
L
E
Y
Y
S
F
Y
Q
S
A
Site 39
Y570
R
E
N
R
L
E
Y
Y
S
F
Y
Q
S
A
R
Site 40
S571
E
N
R
L
E
Y
Y
S
F
Y
Q
S
A
R
Y
Site 41
Y573
R
L
E
Y
Y
S
F
Y
Q
S
A
R
Y
N
V
Site 42
Y578
S
F
Y
Q
S
A
R
Y
N
V
T
A
S
I
C
Site 43
S583
A
R
Y
N
V
T
A
S
I
C
N
T
S
P
N
Site 44
T587
V
T
A
S
I
C
N
T
S
P
N
S
L
E
S
Site 45
S588
T
A
S
I
C
N
T
S
P
N
S
L
E
S
P
Site 46
S591
I
C
N
T
S
P
N
S
L
E
S
P
G
L
E
Site 47
S594
T
S
P
N
S
L
E
S
P
G
L
E
Q
I
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation