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Updated November 2019
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Protein Info
Short Name:
C15orf42
Full Name:
Treslin
Alias:
CDNA, FLJ96860; Chromosome 15 open reading frame 42; CO042; FLJ41618; MGC45866
Type:
Unknown function
Mass (Da):
210857
Number AA:
1910
UniProt ID:
Q7Z2Z1
International Prot ID:
IPI00853221
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S21
A
G
G
A
A
R
H
S
R
V
R
R
A
A
L
Site 2
S52
W
A
F
K
F
F
D
S
Q
G
A
R
S
R
P
Site 3
S57
F
D
S
Q
G
A
R
S
R
P
S
R
V
S
D
Site 4
S60
Q
G
A
R
S
R
P
S
R
V
S
D
F
R
E
Site 5
S63
R
S
R
P
S
R
V
S
D
F
R
E
L
G
S
Site 6
S72
F
R
E
L
G
S
R
S
W
E
D
F
E
E
E
Site 7
T98
P
G
P
A
P
R
A
T
H
T
H
G
A
L
M
Site 8
Y111
L
M
E
T
L
L
D
Y
Q
W
D
R
P
E
I
Site 9
S120
W
D
R
P
E
I
T
S
P
T
K
P
I
L
R
Site 10
S129
T
K
P
I
L
R
S
S
G
R
R
L
L
D
V
Site 11
S138
R
R
L
L
D
V
E
S
E
A
K
E
A
E
A
Site 12
S163
L
L
A
P
C
P
H
S
Q
R
E
L
L
Q
F
Site 13
S172
R
E
L
L
Q
F
V
S
G
C
E
A
Q
A
Q
Site 14
T184
Q
A
Q
R
L
P
P
T
P
K
Q
V
M
E
K
Site 15
Y228
E
S
P
D
H
L
G
Y
W
T
V
C
E
L
L
Site 16
S245
G
G
G
T
V
L
P
S
E
S
F
S
W
D
F
Site 17
S247
G
T
V
L
P
S
E
S
F
S
W
D
F
A
Q
Site 18
S249
V
L
P
S
E
S
F
S
W
D
F
A
Q
A
G
Site 19
S262
A
G
E
M
L
L
R
S
G
I
K
L
S
S
E
Site 20
S267
L
R
S
G
I
K
L
S
S
E
P
H
L
S
P
Site 21
S268
R
S
G
I
K
L
S
S
E
P
H
L
S
P
W
Site 22
S273
L
S
S
E
P
H
L
S
P
W
I
S
M
L
P
Site 23
S277
P
H
L
S
P
W
I
S
M
L
P
T
D
A
T
Site 24
T284
S
M
L
P
T
D
A
T
L
N
R
L
L
Y
N
Site 25
Y290
A
T
L
N
R
L
L
Y
N
S
P
E
Y
E
A
Site 26
S292
L
N
R
L
L
Y
N
S
P
E
Y
E
A
S
F
Site 27
Y295
L
L
Y
N
S
P
E
Y
E
A
S
F
P
R
M
Site 28
S298
N
S
P
E
Y
E
A
S
F
P
R
M
E
G
M
Site 29
T319
A
G
K
E
I
Q
E
T
W
T
V
T
L
E
P
Site 30
T321
K
E
I
Q
E
T
W
T
V
T
L
E
P
L
A
Site 31
S350
K
G
S
V
A
Q
W
S
L
P
T
S
S
T
L
Site 32
S354
A
Q
W
S
L
P
T
S
S
T
L
G
T
D
S
Site 33
S355
Q
W
S
L
P
T
S
S
T
L
G
T
D
S
W
Site 34
T356
W
S
L
P
T
S
S
T
L
G
T
D
S
W
M
Site 35
T359
P
T
S
S
T
L
G
T
D
S
W
M
L
G
S
Site 36
S361
S
S
T
L
G
T
D
S
W
M
L
G
S
P
E
Site 37
S366
T
D
S
W
M
L
G
S
P
E
E
S
T
A
T
Site 38
S370
M
L
G
S
P
E
E
S
T
A
T
Q
R
L
L
Site 39
T373
S
P
E
E
S
T
A
T
Q
R
L
L
F
Q
Q
Site 40
T406
G
E
G
R
P
P
I
T
G
V
I
S
P
L
S
Site 41
T436
F
Q
R
H
V
L
Q
T
A
V
A
D
S
P
R
Site 42
S441
L
Q
T
A
V
A
D
S
P
R
D
T
A
S
L
Site 43
T445
V
A
D
S
P
R
D
T
A
S
L
F
S
D
V
Site 44
S447
D
S
P
R
D
T
A
S
L
F
S
D
V
V
D
Site 45
S455
L
F
S
D
V
V
D
S
I
L
N
Q
T
H
D
Site 46
S463
I
L
N
Q
T
H
D
S
L
A
D
T
A
S
A
Site 47
T467
T
H
D
S
L
A
D
T
A
S
A
A
S
P
V
Site 48
S469
D
S
L
A
D
T
A
S
A
A
S
P
V
P
E
Site 49
S472
A
D
T
A
S
A
A
S
P
V
P
E
W
A
Q
Site 50
T485
A
Q
Q
E
L
G
H
T
T
P
W
S
P
A
V
Site 51
T486
Q
Q
E
L
G
H
T
T
P
W
S
P
A
V
V
Site 52
S489
L
G
H
T
T
P
W
S
P
A
V
V
E
K
W
Site 53
S507
C
N
I
S
G
A
S
S
D
L
M
E
S
F
G
Site 54
S520
F
G
L
L
Q
A
A
S
A
N
K
E
E
S
S
Site 55
T529
N
K
E
E
S
S
K
T
E
G
E
L
I
H
C
Site 56
Y541
I
H
C
L
A
E
L
Y
Q
R
K
S
R
E
E
Site 57
S545
A
E
L
Y
Q
R
K
S
R
E
E
S
T
I
A
Site 58
S549
Q
R
K
S
R
E
E
S
T
I
A
H
Q
E
D
Site 59
S557
T
I
A
H
Q
E
D
S
K
K
K
R
G
V
P
Site 60
T566
K
K
R
G
V
P
R
T
P
V
R
Q
K
M
N
Site 61
T574
P
V
R
Q
K
M
N
T
M
C
R
S
L
K
M
Site 62
S599
Q
K
L
H
P
D
G
S
P
D
V
A
G
E
K
Site 63
S613
K
G
I
Q
K
I
P
S
G
R
T
V
D
K
L
Site 64
T626
K
L
E
D
R
G
R
T
L
R
S
S
K
P
K
Site 65
S630
R
G
R
T
L
R
S
S
K
P
K
D
F
K
T
Site 66
T637
S
K
P
K
D
F
K
T
E
E
E
L
L
S
Y
Site 67
S643
K
T
E
E
E
L
L
S
Y
I
R
E
N
Y
Q
Site 68
Y644
T
E
E
E
L
L
S
Y
I
R
E
N
Y
Q
K
Site 69
Y649
L
S
Y
I
R
E
N
Y
Q
K
T
V
A
T
G
Site 70
T652
I
R
E
N
Y
Q
K
T
V
A
T
G
E
I
M
Site 71
S677
T
V
K
M
F
L
K
S
K
G
T
K
E
L
E
Site 72
T680
M
F
L
K
S
K
G
T
K
E
L
E
V
N
C
Site 73
S693
N
C
L
N
Q
V
K
S
S
L
L
K
T
S
K
Site 74
S694
C
L
N
Q
V
K
S
S
L
L
K
T
S
K
S
Site 75
T698
V
K
S
S
L
L
K
T
S
K
S
L
R
Q
N
Site 76
S701
S
L
L
K
T
S
K
S
L
R
Q
N
L
G
K
Site 77
S735
E
M
C
L
Q
C
P
S
I
N
E
S
T
D
D
Site 78
S739
Q
C
P
S
I
N
E
S
T
D
D
M
E
Q
V
Site 79
Y765
C
L
T
E
D
S
A
Y
L
A
E
F
L
E
E
Site 80
T784
Y
I
D
S
I
P
K
T
L
G
N
L
Y
N
S
Site 81
S810
V
L
P
T
D
F
F
S
D
D
S
M
T
Q
E
Site 82
S813
T
D
F
F
S
D
D
S
M
T
Q
E
N
K
S
Site 83
T815
F
F
S
D
D
S
M
T
Q
E
N
K
S
P
L
Site 84
S820
S
M
T
Q
E
N
K
S
P
L
L
S
V
P
F
Site 85
S824
E
N
K
S
P
L
L
S
V
P
F
L
S
S
A
Site 86
S834
F
L
S
S
A
R
R
S
V
S
G
S
P
E
S
Site 87
S836
S
S
A
R
R
S
V
S
G
S
P
E
S
D
E
Site 88
S838
A
R
R
S
V
S
G
S
P
E
S
D
E
L
Q
Site 89
S841
S
V
S
G
S
P
E
S
D
E
L
Q
E
L
R
Site 90
S851
L
Q
E
L
R
T
R
S
A
K
K
R
R
K
N
Site 91
S865
N
A
L
I
R
H
K
S
I
A
E
V
S
Q
N
Site 92
S882
Q
I
E
I
P
K
V
S
K
R
A
T
K
K
E
Site 93
T886
P
K
V
S
K
R
A
T
K
K
E
N
S
H
P
Site 94
S899
H
P
A
P
Q
Q
P
S
Q
P
V
K
D
T
V
Site 95
T905
P
S
Q
P
V
K
D
T
V
Q
E
V
T
K
V
Site 96
S923
L
F
N
Q
E
L
L
S
P
S
K
R
S
L
K
Site 97
S925
N
Q
E
L
L
S
P
S
K
R
S
L
K
R
G
Site 98
S928
L
L
S
P
S
K
R
S
L
K
R
G
L
P
R
Site 99
S936
L
K
R
G
L
P
R
S
H
S
V
S
A
V
D
Site 100
S938
R
G
L
P
R
S
H
S
V
S
A
V
D
G
L
Site 101
S940
L
P
R
S
H
S
V
S
A
V
D
G
L
E
D
Site 102
T963
K
G
Y
H
K
L
L
T
K
S
V
A
E
T
P
Site 103
S965
Y
H
K
L
L
T
K
S
V
A
E
T
P
V
H
Site 104
T969
L
T
K
S
V
A
E
T
P
V
H
K
Q
I
S
Site 105
S976
T
P
V
H
K
Q
I
S
K
R
L
L
H
R
Q
Site 106
S989
R
Q
I
K
G
R
S
S
D
P
G
P
D
I
G
Site 107
S1001
D
I
G
V
V
E
E
S
P
E
K
G
D
E
I
Site 108
S1009
P
E
K
G
D
E
I
S
L
R
R
S
P
R
I
Site 109
S1013
D
E
I
S
L
R
R
S
P
R
I
K
Q
L
S
Site 110
S1020
S
P
R
I
K
Q
L
S
F
S
R
T
H
S
A
Site 111
S1022
R
I
K
Q
L
S
F
S
R
T
H
S
A
S
F
Site 112
T1024
K
Q
L
S
F
S
R
T
H
S
A
S
F
Y
S
Site 113
S1026
L
S
F
S
R
T
H
S
A
S
F
Y
S
V
S
Site 114
S1028
F
S
R
T
H
S
A
S
F
Y
S
V
S
Q
P
Site 115
Y1030
R
T
H
S
A
S
F
Y
S
V
S
Q
P
K
S
Site 116
S1031
T
H
S
A
S
F
Y
S
V
S
Q
P
K
S
R
Site 117
S1033
S
A
S
F
Y
S
V
S
Q
P
K
S
R
S
V
Site 118
S1037
Y
S
V
S
Q
P
K
S
R
S
V
Q
R
V
H
Site 119
S1039
V
S
Q
P
K
S
R
S
V
Q
R
V
H
S
F
Site 120
S1045
R
S
V
Q
R
V
H
S
F
Q
Q
D
K
S
D
Site 121
S1051
H
S
F
Q
Q
D
K
S
D
Q
R
E
N
S
P
Site 122
S1057
K
S
D
Q
R
E
N
S
P
V
Q
S
I
R
S
Site 123
S1061
R
E
N
S
P
V
Q
S
I
R
S
P
K
S
L
Site 124
S1064
S
P
V
Q
S
I
R
S
P
K
S
L
L
F
G
Site 125
S1067
Q
S
I
R
S
P
K
S
L
L
F
G
A
M
S
Site 126
S1078
G
A
M
S
E
M
I
S
P
S
E
K
G
S
A
Site 127
S1080
M
S
E
M
I
S
P
S
E
K
G
S
A
R
M
Site 128
S1084
I
S
P
S
E
K
G
S
A
R
M
K
K
R
S
Site 129
S1091
S
A
R
M
K
K
R
S
R
N
T
L
D
S
E
Site 130
T1094
M
K
K
R
S
R
N
T
L
D
S
E
V
P
A
Site 131
S1097
R
S
R
N
T
L
D
S
E
V
P
A
A
Y
Q
Site 132
Y1103
D
S
E
V
P
A
A
Y
Q
T
P
K
K
S
H
Site 133
T1105
E
V
P
A
A
Y
Q
T
P
K
K
S
H
Q
K
Site 134
S1109
A
Y
Q
T
P
K
K
S
H
Q
K
S
L
S
F
Site 135
S1113
P
K
K
S
H
Q
K
S
L
S
F
S
K
T
T
Site 136
S1115
K
S
H
Q
K
S
L
S
F
S
K
T
T
P
R
Site 137
S1117
H
Q
K
S
L
S
F
S
K
T
T
P
R
R
I
Site 138
T1119
K
S
L
S
F
S
K
T
T
P
R
R
I
S
H
Site 139
T1120
S
L
S
F
S
K
T
T
P
R
R
I
S
H
T
Site 140
S1125
K
T
T
P
R
R
I
S
H
T
P
Q
T
P
L
Site 141
T1127
T
P
R
R
I
S
H
T
P
Q
T
P
L
Y
T
Site 142
T1130
R
I
S
H
T
P
Q
T
P
L
Y
T
P
E
R
Site 143
Y1133
H
T
P
Q
T
P
L
Y
T
P
E
R
L
Q
K
Site 144
T1134
T
P
Q
T
P
L
Y
T
P
E
R
L
Q
K
S
Site 145
S1141
T
P
E
R
L
Q
K
S
P
A
K
M
T
P
T
Site 146
T1146
Q
K
S
P
A
K
M
T
P
T
K
Q
A
A
F
Site 147
S1156
K
Q
A
A
F
K
E
S
L
K
D
S
S
S
P
Site 148
S1160
F
K
E
S
L
K
D
S
S
S
P
G
H
D
S
Site 149
S1161
K
E
S
L
K
D
S
S
S
P
G
H
D
S
P
Site 150
S1162
E
S
L
K
D
S
S
S
P
G
H
D
S
P
L
Site 151
S1167
S
S
S
P
G
H
D
S
P
L
D
S
K
I
T
Site 152
S1171
G
H
D
S
P
L
D
S
K
I
T
P
Q
K
R
Site 153
T1174
S
P
L
D
S
K
I
T
P
Q
K
R
H
T
Q
Site 154
T1180
I
T
P
Q
K
R
H
T
Q
A
G
E
G
T
S
Site 155
T1186
H
T
Q
A
G
E
G
T
S
L
E
T
K
T
P
Site 156
S1187
T
Q
A
G
E
G
T
S
L
E
T
K
T
P
R
Site 157
T1192
G
T
S
L
E
T
K
T
P
R
T
P
K
R
Q
Site 158
T1195
L
E
T
K
T
P
R
T
P
K
R
Q
G
T
Q
Site 159
T1201
R
T
P
K
R
Q
G
T
Q
P
P
G
F
L
P
Site 160
S1215
P
N
C
T
W
P
H
S
V
N
S
S
P
E
S
Site 161
S1218
T
W
P
H
S
V
N
S
S
P
E
S
P
S
C
Site 162
S1219
W
P
H
S
V
N
S
S
P
E
S
P
S
C
P
Site 163
S1222
S
V
N
S
S
P
E
S
P
S
C
P
A
P
P
Site 164
S1224
N
S
S
P
E
S
P
S
C
P
A
P
P
T
S
Site 165
T1230
P
S
C
P
A
P
P
T
S
S
T
A
Q
P
R
Site 166
S1231
S
C
P
A
P
P
T
S
S
T
A
Q
P
R
R
Site 167
T1233
P
A
P
P
T
S
S
T
A
Q
P
R
R
E
C
Site 168
T1242
Q
P
R
R
E
C
L
T
P
I
R
D
P
L
R
Site 169
T1250
P
I
R
D
P
L
R
T
P
P
R
A
A
A
F
Site 170
T1260
R
A
A
A
F
M
G
T
P
Q
N
Q
T
H
Q
Site 171
T1291
L
K
D
K
A
I
K
T
P
K
R
P
G
N
S
Site 172
S1298
T
P
K
R
P
G
N
S
T
V
T
S
S
P
P
Site 173
T1299
P
K
R
P
G
N
S
T
V
T
S
S
P
P
V
Site 174
T1301
R
P
G
N
S
T
V
T
S
S
P
P
V
T
P
Site 175
S1302
P
G
N
S
T
V
T
S
S
P
P
V
T
P
K
Site 176
S1303
G
N
S
T
V
T
S
S
P
P
V
T
P
K
K
Site 177
T1307
V
T
S
S
P
P
V
T
P
K
K
L
F
T
S
Site 178
S1314
T
P
K
K
L
F
T
S
P
L
C
D
V
S
K
Site 179
S1320
T
S
P
L
C
D
V
S
K
K
S
P
F
R
K
Site 180
S1323
L
C
D
V
S
K
K
S
P
F
R
K
S
K
I
Site 181
S1328
K
K
S
P
F
R
K
S
K
I
E
C
P
S
P
Site 182
S1334
K
S
K
I
E
C
P
S
P
G
E
L
D
Q
K
Site 183
S1346
D
Q
K
E
P
Q
M
S
P
S
V
A
A
S
L
Site 184
S1348
K
E
P
Q
M
S
P
S
V
A
A
S
L
S
C
Site 185
S1359
S
L
S
C
P
V
P
S
T
P
P
E
L
S
Q
Site 186
T1360
L
S
C
P
V
P
S
T
P
P
E
L
S
Q
R
Site 187
S1365
P
S
T
P
P
E
L
S
Q
R
A
T
L
D
T
Site 188
T1369
P
E
L
S
Q
R
A
T
L
D
T
V
P
P
P
Site 189
T1372
S
Q
R
A
T
L
D
T
V
P
P
P
P
P
S
Site 190
S1379
T
V
P
P
P
P
P
S
K
V
G
K
R
C
R
Site 191
T1388
V
G
K
R
C
R
K
T
S
D
P
R
R
S
I
Site 192
S1389
G
K
R
C
R
K
T
S
D
P
R
R
S
I
V
Site 193
S1394
K
T
S
D
P
R
R
S
I
V
E
C
Q
P
D
Site 194
S1403
V
E
C
Q
P
D
A
S
A
T
P
G
V
G
T
Site 195
T1405
C
Q
P
D
A
S
A
T
P
G
V
G
T
A
D
Site 196
S1413
P
G
V
G
T
A
D
S
P
A
A
P
T
D
S
Site 197
S1420
S
P
A
A
P
T
D
S
R
D
D
Q
K
G
L
Site 198
S1428
R
D
D
Q
K
G
L
S
L
S
P
Q
S
P
P
Site 199
S1430
D
Q
K
G
L
S
L
S
P
Q
S
P
P
E
R
Site 200
S1433
G
L
S
L
S
P
Q
S
P
P
E
R
R
G
Y
Site 201
Y1440
S
P
P
E
R
R
G
Y
P
G
P
G
L
R
S
Site 202
S1447
Y
P
G
P
G
L
R
S
D
W
H
A
S
S
P
Site 203
S1453
R
S
D
W
H
A
S
S
P
L
L
I
T
S
D
Site 204
S1480
H
G
I
G
D
L
K
S
N
V
L
S
V
E
E
Site 205
S1484
D
L
K
S
N
V
L
S
V
E
E
G
E
G
L
Site 206
T1493
E
E
G
E
G
L
R
T
A
D
A
E
K
S
S
Site 207
S1499
R
T
A
D
A
E
K
S
S
L
S
H
P
G
I
Site 208
S1500
T
A
D
A
E
K
S
S
L
S
H
P
G
I
P
Site 209
S1502
D
A
E
K
S
S
L
S
H
P
G
I
P
P
S
Site 210
S1509
S
H
P
G
I
P
P
S
P
P
S
C
G
P
G
Site 211
S1512
G
I
P
P
S
P
P
S
C
G
P
G
S
P
L
Site 212
S1517
P
P
S
C
G
P
G
S
P
L
M
P
S
R
D
Site 213
S1522
P
G
S
P
L
M
P
S
R
D
V
H
C
T
T
Site 214
T1529
S
R
D
V
H
C
T
T
D
G
R
Q
C
Q
A
Site 215
S1537
D
G
R
Q
C
Q
A
S
A
Q
L
D
N
L
P
Site 216
S1546
Q
L
D
N
L
P
A
S
A
W
H
S
T
D
S
Site 217
S1550
L
P
A
S
A
W
H
S
T
D
S
A
S
P
Q
Site 218
T1551
P
A
S
A
W
H
S
T
D
S
A
S
P
Q
T
Site 219
S1553
S
A
W
H
S
T
D
S
A
S
P
Q
T
Y
E
Site 220
S1555
W
H
S
T
D
S
A
S
P
Q
T
Y
E
V
E
Site 221
Y1559
D
S
A
S
P
Q
T
Y
E
V
E
L
E
M
Q
Site 222
S1582
I
K
K
I
D
P
S
S
S
L
E
A
E
P
L
Site 223
S1583
K
K
I
D
P
S
S
S
L
E
A
E
P
L
S
Site 224
S1590
S
L
E
A
E
P
L
S
K
E
E
S
S
L
G
Site 225
S1594
E
P
L
S
K
E
E
S
S
L
G
E
E
S
F
Site 226
S1595
P
L
S
K
E
E
S
S
L
G
E
E
S
F
L
Site 227
S1600
E
S
S
L
G
E
E
S
F
L
P
A
L
S
M
Site 228
S1606
E
S
F
L
P
A
L
S
M
P
R
A
S
R
S
Site 229
S1611
A
L
S
M
P
R
A
S
R
S
L
S
K
P
E
Site 230
S1613
S
M
P
R
A
S
R
S
L
S
K
P
E
P
T
Site 231
S1615
P
R
A
S
R
S
L
S
K
P
E
P
T
Y
V
Site 232
T1620
S
L
S
K
P
E
P
T
Y
V
S
P
P
C
P
Site 233
Y1621
L
S
K
P
E
P
T
Y
V
S
P
P
C
P
R
Site 234
S1623
K
P
E
P
T
Y
V
S
P
P
C
P
R
L
S
Site 235
S1630
S
P
P
C
P
R
L
S
H
S
T
P
G
K
S
Site 236
S1632
P
C
P
R
L
S
H
S
T
P
G
K
S
R
G
Site 237
T1633
C
P
R
L
S
H
S
T
P
G
K
S
R
G
Q
Site 238
S1637
S
H
S
T
P
G
K
S
R
G
Q
T
Y
I
C
Site 239
T1641
P
G
K
S
R
G
Q
T
Y
I
C
Q
A
C
T
Site 240
Y1642
G
K
S
R
G
Q
T
Y
I
C
Q
A
C
T
P
Site 241
T1648
T
Y
I
C
Q
A
C
T
P
T
H
G
P
S
S
Site 242
T1650
I
C
Q
A
C
T
P
T
H
G
P
S
S
T
P
Site 243
S1654
C
T
P
T
H
G
P
S
S
T
P
S
P
F
Q
Site 244
S1655
T
P
T
H
G
P
S
S
T
P
S
P
F
Q
T
Site 245
T1656
P
T
H
G
P
S
S
T
P
S
P
F
Q
T
D
Site 246
S1658
H
G
P
S
S
T
P
S
P
F
Q
T
D
G
V
Site 247
T1662
S
T
P
S
P
F
Q
T
D
G
V
P
W
T
P
Site 248
T1668
Q
T
D
G
V
P
W
T
P
S
P
K
H
S
G
Site 249
S1670
D
G
V
P
W
T
P
S
P
K
H
S
G
K
T
Site 250
S1674
W
T
P
S
P
K
H
S
G
K
T
T
P
D
I
Site 251
T1678
P
K
H
S
G
K
T
T
P
D
I
I
K
D
W
Site 252
S1698
A
V
G
C
G
A
G
S
S
S
G
R
G
E
V
Site 253
S1699
V
G
C
G
A
G
S
S
S
G
R
G
E
V
G
Site 254
S1700
G
C
G
A
G
S
S
S
G
R
G
E
V
G
A
Site 255
S1714
A
D
L
P
G
S
L
S
L
L
E
S
E
G
K
Site 256
S1718
G
S
L
S
L
L
E
S
E
G
K
D
H
G
L
Site 257
S1728
K
D
H
G
L
E
L
S
I
H
R
T
P
I
L
Site 258
T1732
L
E
L
S
I
H
R
T
P
I
L
E
D
F
E
Site 259
S1750
V
C
Q
L
P
D
Q
S
P
P
R
N
S
M
P
Site 260
S1755
D
Q
S
P
P
R
N
S
M
P
K
A
E
E
A
Site 261
S1764
P
K
A
E
E
A
S
S
W
G
Q
F
G
L
S
Site 262
S1771
S
W
G
Q
F
G
L
S
S
R
K
R
V
L
L
Site 263
S1772
W
G
Q
F
G
L
S
S
R
K
R
V
L
L
A
Site 264
S1797
I
C
D
L
R
E
D
S
E
V
S
K
S
K
E
Site 265
S1800
L
R
E
D
S
E
V
S
K
S
K
E
G
S
P
Site 266
S1802
E
D
S
E
V
S
K
S
K
E
G
S
P
S
W
Site 267
S1806
V
S
K
S
K
E
G
S
P
S
W
S
A
W
Q
Site 268
S1808
K
S
K
E
G
S
P
S
W
S
A
W
Q
L
P
Site 269
S1810
K
E
G
S
P
S
W
S
A
W
Q
L
P
S
T
Site 270
T1817
S
A
W
Q
L
P
S
T
G
D
E
E
V
F
V
Site 271
S1825
G
D
E
E
V
F
V
S
G
S
T
P
P
P
S
Site 272
S1827
E
E
V
F
V
S
G
S
T
P
P
P
S
C
A
Site 273
S1832
S
G
S
T
P
P
P
S
C
A
V
R
S
C
L
Site 274
T1858
P
L
L
F
Q
G
K
T
P
S
S
Q
S
K
D
Site 275
S1860
L
F
Q
G
K
T
P
S
S
Q
S
K
D
P
R
Site 276
S1861
F
Q
G
K
T
P
S
S
Q
S
K
D
P
R
D
Site 277
S1863
G
K
T
P
S
S
Q
S
K
D
P
R
D
E
D
Site 278
T1877
D
V
D
V
L
P
S
T
V
E
D
S
P
F
S
Site 279
S1881
L
P
S
T
V
E
D
S
P
F
S
R
A
F
S
Site 280
S1884
T
V
E
D
S
P
F
S
R
A
F
S
R
R
R
Site 281
S1888
S
P
F
S
R
A
F
S
R
R
R
P
I
S
R
Site 282
S1894
F
S
R
R
R
P
I
S
R
T
Y
T
R
K
K
Site 283
T1896
R
R
R
P
I
S
R
T
Y
T
R
K
K
L
M
Site 284
Y1897
R
R
P
I
S
R
T
Y
T
R
K
K
L
M
G
Site 285
T1898
R
P
I
S
R
T
Y
T
R
K
K
L
M
G
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation