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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MAMDC2
Full Name:
MAM domain-containing protein 2
Alias:
MAM domain-containing proteoglycan
Type:
Mass (Da):
77583
Number AA:
686
UniProt ID:
Q7Z304
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S31
G
S
C
A
F
E
E
S
T
C
G
F
D
S
V
Site 2
Y52
I
L
N
E
E
G
H
Y
I
Y
V
D
T
S
F
Site 3
Y54
N
E
E
G
H
Y
I
Y
V
D
T
S
F
G
K
Site 4
S70
G
E
K
A
V
L
L
S
P
D
L
Q
A
E
E
Site 5
Y85
W
S
C
L
R
L
V
Y
Q
I
T
T
S
S
E
Site 6
T88
L
R
L
V
Y
Q
I
T
T
S
S
E
S
L
S
Site 7
T89
R
L
V
Y
Q
I
T
T
S
S
E
S
L
S
D
Site 8
S90
L
V
Y
Q
I
T
T
S
S
E
S
L
S
D
P
Site 9
S91
V
Y
Q
I
T
T
S
S
E
S
L
S
D
P
S
Site 10
S93
Q
I
T
T
S
S
E
S
L
S
D
P
S
Q
L
Site 11
S95
T
T
S
S
E
S
L
S
D
P
S
Q
L
N
L
Site 12
S98
S
E
S
L
S
D
P
S
Q
L
N
L
Y
M
R
Site 13
Y103
D
P
S
Q
L
N
L
Y
M
R
F
E
D
E
S
Site 14
S110
Y
M
R
F
E
D
E
S
F
D
R
L
L
W
S
Site 15
S117
S
F
D
R
L
L
W
S
A
K
E
P
S
D
S
Site 16
S122
L
W
S
A
K
E
P
S
D
S
W
L
I
A
S
Site 17
S124
S
A
K
E
P
S
D
S
W
L
I
A
S
L
D
Site 18
S129
S
D
S
W
L
I
A
S
L
D
L
Q
N
S
S
Site 19
S135
A
S
L
D
L
Q
N
S
S
K
K
F
K
I
L
Site 20
T209
S
I
L
P
Q
D
H
T
F
K
S
E
L
G
H
Site 21
Y217
F
K
S
E
L
G
H
Y
M
Y
V
D
S
V
Y
Site 22
Y219
S
E
L
G
H
Y
M
Y
V
D
S
V
Y
V
K
Site 23
Y224
Y
M
Y
V
D
S
V
Y
V
K
H
F
Q
E
V
Site 24
Y250
M
A
G
C
L
S
F
Y
Y
Q
I
Q
Q
G
N
Site 25
Y251
A
G
C
L
S
F
Y
Y
Q
I
Q
Q
G
N
D
Site 26
S262
Q
G
N
D
N
V
F
S
L
Y
T
R
D
V
A
Site 27
Y264
N
D
N
V
F
S
L
Y
T
R
D
V
A
G
L
Site 28
Y272
T
R
D
V
A
G
L
Y
E
E
I
W
K
A
D
Site 29
Y297
E
V
E
F
N
A
P
Y
P
M
E
V
I
F
E
Site 30
Y314
F
N
G
P
K
G
G
Y
V
A
L
D
D
I
S
Site 31
S323
A
L
D
D
I
S
F
S
P
V
H
C
Q
N
Q
Site 32
S336
N
Q
T
E
L
L
F
S
A
V
E
A
S
C
N
Site 33
Y352
E
Q
D
L
C
N
F
Y
Q
D
K
E
G
P
G
Site 34
T376
M
Y
R
A
G
D
H
T
T
G
L
G
Y
Y
L
Site 35
Y382
H
T
T
G
L
G
Y
Y
L
L
A
N
T
K
F
Site 36
S391
L
A
N
T
K
F
T
S
Q
P
G
Y
I
G
R
Site 37
Y395
K
F
T
S
Q
P
G
Y
I
G
R
L
Y
G
P
Site 38
Y400
P
G
Y
I
G
R
L
Y
G
P
S
L
P
G
N
Site 39
S403
I
G
R
L
Y
G
P
S
L
P
G
N
L
Q
Y
Site 40
Y410
S
L
P
G
N
L
Q
Y
C
L
R
F
H
Y
A
Site 41
S425
I
Y
G
F
L
K
M
S
D
T
L
A
V
Y
I
Site 42
S445
V
V
Q
E
K
I
W
S
V
L
E
S
P
R
G
Site 43
S449
K
I
W
S
V
L
E
S
P
R
G
V
W
M
Q
Site 44
T460
V
W
M
Q
A
E
I
T
F
K
K
P
M
P
T
Site 45
S495
D
I
T
I
Q
L
G
S
C
S
S
S
E
K
L
Site 46
S497
T
I
Q
L
G
S
C
S
S
S
E
K
L
P
P
Site 47
S498
I
Q
L
G
S
C
S
S
S
E
K
L
P
P
P
Site 48
S499
Q
L
G
S
C
S
S
S
E
K
L
P
P
P
P
Site 49
T510
P
P
P
P
G
E
C
T
F
E
Q
D
E
C
T
Site 50
T517
T
F
E
Q
D
E
C
T
F
T
Q
E
K
R
N
Site 51
T519
E
Q
D
E
C
T
F
T
Q
E
K
R
N
R
S
Site 52
S526
T
Q
E
K
R
N
R
S
S
W
H
R
R
R
G
Site 53
S527
Q
E
K
R
N
R
S
S
W
H
R
R
R
G
E
Site 54
T535
W
H
R
R
R
G
E
T
P
T
S
Y
T
G
P
Site 55
T537
R
R
R
G
E
T
P
T
S
Y
T
G
P
K
G
Site 56
S538
R
R
G
E
T
P
T
S
Y
T
G
P
K
G
D
Site 57
Y539
R
G
E
T
P
T
S
Y
T
G
P
K
G
D
H
Site 58
T547
T
G
P
K
G
D
H
T
T
G
V
G
Y
Y
M
Site 59
T548
G
P
K
G
D
H
T
T
G
V
G
Y
Y
M
Y
Site 60
Y553
H
T
T
G
V
G
Y
Y
M
Y
I
E
A
S
H
Site 61
Y563
I
E
A
S
H
M
V
Y
G
Q
K
A
R
L
L
Site 62
S571
G
Q
K
A
R
L
L
S
R
P
L
R
G
V
S
Site 63
S578
S
R
P
L
R
G
V
S
G
K
H
C
L
T
F
Site 64
S598
G
G
G
T
G
L
L
S
V
Y
L
K
K
E
E
Site 65
Y600
G
T
G
L
L
S
V
Y
L
K
K
E
E
D
S
Site 66
S607
Y
L
K
K
E
E
D
S
E
E
S
L
L
W
R
Site 67
S620
W
R
R
R
G
E
Q
S
I
S
W
L
R
A
L
Site 68
S622
R
R
G
E
Q
S
I
S
W
L
R
A
L
I
E
Site 69
Y630
W
L
R
A
L
I
E
Y
S
C
E
R
Q
H
Q
Site 70
T670
P
C
G
E
M
E
D
T
T
Q
Q
S
S
G
Y
Site 71
T671
C
G
E
M
E
D
T
T
Q
Q
S
S
G
Y
S
Site 72
S678
T
Q
Q
S
S
G
Y
S
E
D
L
N
E
I
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation