KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
DPY19L4
Full Name:
Protein dpy-19 homolog 4
Alias:
Dpy-19-like protein 4
Type:
Mass (Da):
83756
Number AA:
723
UniProt ID:
Q7Z388
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
R
Q
R
K
K
P
K
S
S
E
N
K
E
S
A
Site 2
S20
Q
R
K
K
P
K
S
S
E
N
K
E
S
A
K
Site 3
S25
K
S
S
E
N
K
E
S
A
K
E
E
K
I
S
Site 4
S32
S
A
K
E
E
K
I
S
D
I
P
I
P
E
R
Site 5
Y69
S
G
M
M
Y
A
L
Y
L
S
A
Y
H
E
R
Site 6
Y73
Y
A
L
Y
L
S
A
Y
H
E
R
K
F
W
F
Site 7
S81
H
E
R
K
F
W
F
S
N
R
Q
E
L
E
R
Site 8
T91
Q
E
L
E
R
E
I
T
F
Q
G
D
S
A
I
Site 9
Y99
F
Q
G
D
S
A
I
Y
Y
S
Y
Y
K
D
M
Site 10
Y100
Q
G
D
S
A
I
Y
Y
S
Y
Y
K
D
M
L
Site 11
Y103
S
A
I
Y
Y
S
Y
Y
K
D
M
L
K
A
P
Site 12
S111
K
D
M
L
K
A
P
S
F
E
R
G
V
Y
E
Site 13
Y117
P
S
F
E
R
G
V
Y
E
L
T
H
N
N
K
Site 14
T120
E
R
G
V
Y
E
L
T
H
N
N
K
T
V
S
Site 15
T125
E
L
T
H
N
N
K
T
V
S
L
K
T
I
N
Site 16
S127
T
H
N
N
K
T
V
S
L
K
T
I
N
A
V
Site 17
Y212
V
D
T
T
R
I
E
Y
S
I
P
L
R
E
N
Site 18
Y235
Q
I
A
A
L
T
G
Y
L
K
S
N
L
N
T
Site 19
S238
A
L
T
G
Y
L
K
S
N
L
N
T
Y
G
E
Site 20
T242
Y
L
K
S
N
L
N
T
Y
G
E
R
F
C
Y
Site 21
Y243
L
K
S
N
L
N
T
Y
G
E
R
F
C
Y
L
Site 22
S288
D
T
F
S
V
E
Q
S
D
K
V
Y
E
V
Y
Site 23
Y292
V
E
Q
S
D
K
V
Y
E
V
Y
K
I
Y
I
Site 24
S404
N
W
L
L
C
Q
E
S
L
Q
A
P
S
Q
D
Site 25
S409
Q
E
S
L
Q
A
P
S
Q
D
F
F
L
R
L
Site 26
S448
F
R
R
I
N
G
K
S
L
K
E
T
V
T
L
Site 27
T452
N
G
K
S
L
K
E
T
V
T
L
E
D
G
R
Site 28
T454
K
S
L
K
E
T
V
T
L
E
D
G
R
I
G
Site 29
T551
E
F
F
P
R
L
M
T
E
L
M
E
L
Q
E
Site 30
Y605
M
V
T
S
L
P
L
Y
N
D
D
D
L
L
K
Site 31
Y618
L
K
R
N
E
N
I
Y
Q
I
Y
S
K
R
S
Site 32
S622
E
N
I
Y
Q
I
Y
S
K
R
S
A
E
D
I
Site 33
Y630
K
R
S
A
E
D
I
Y
K
I
L
T
S
Y
K
Site 34
T679
C
E
E
G
D
K
L
T
Y
S
K
Y
G
R
F
Site 35
Y683
D
K
L
T
Y
S
K
Y
G
R
F
C
H
E
V
Site 36
Y697
V
K
I
N
Y
S
P
Y
V
N
Y
F
T
R
V
Site 37
Y705
V
N
Y
F
T
R
V
Y
W
N
R
S
Y
F
V
Site 38
Y710
R
V
Y
W
N
R
S
Y
F
V
Y
K
I
N
T
Site 39
Y713
W
N
R
S
Y
F
V
Y
K
I
N
T
V
I
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation