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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NUP54
Full Name:
Nucleoporin p54
Alias:
54 kDa nucleoporin
Type:
Mass (Da):
55417
Number AA:
507
UniProt ID:
Q7Z3B4
International Prot ID:
IPI00172580
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005635
GO:0005643
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006810
GO:0006886
GO:0015031
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T30
G
G
F
G
G
F
G
T
T
S
T
T
A
G
S
Site 2
T33
G
G
F
G
T
T
S
T
T
A
G
S
A
F
S
Site 3
S37
T
T
S
T
T
A
G
S
A
F
S
F
S
A
P
Site 4
S40
T
T
A
G
S
A
F
S
F
S
A
P
T
N
T
Site 5
S42
A
G
S
A
F
S
F
S
A
P
T
N
T
G
T
Site 6
T69
G
F
G
T
G
F
G
T
T
T
G
T
S
T
G
Site 7
T71
G
T
G
F
G
T
T
T
G
T
S
T
G
L
G
Site 8
S105
T
T
L
G
G
L
F
S
Q
P
T
Q
A
P
T
Site 9
T108
G
G
L
F
S
Q
P
T
Q
A
P
T
Q
S
N
Site 10
T112
S
Q
P
T
Q
A
P
T
Q
S
N
Q
L
I
N
Site 11
Y154
F
W
G
T
G
K
G
Y
F
N
N
N
I
P
P
Site 12
S179
R
F
K
A
V
G
Y
S
C
M
P
S
N
K
D
Site 13
S183
V
G
Y
S
C
M
P
S
N
K
D
E
D
G
L
Site 14
S204
K
K
E
T
E
I
R
S
Q
Q
Q
Q
L
V
E
Site 15
S212
Q
Q
Q
Q
L
V
E
S
L
H
K
V
L
G
G
Site 16
T222
K
V
L
G
G
N
Q
T
L
T
V
N
V
E
G
Site 17
T224
L
G
G
N
Q
T
L
T
V
N
V
E
G
T
K
Site 18
T232
V
N
V
E
G
T
K
T
L
P
D
D
Q
T
E
Site 19
Y243
D
Q
T
E
V
V
I
Y
V
V
E
R
S
P
N
Site 20
S248
V
I
Y
V
V
E
R
S
P
N
G
T
S
R
R
Site 21
T252
V
E
R
S
P
N
G
T
S
R
R
V
P
A
T
Site 22
S253
E
R
S
P
N
G
T
S
R
R
V
P
A
T
T
Site 23
T259
T
S
R
R
V
P
A
T
T
L
Y
A
H
F
E
Site 24
T260
S
R
R
V
P
A
T
T
L
Y
A
H
F
E
Q
Site 25
Y262
R
V
P
A
T
T
L
Y
A
H
F
E
Q
A
N
Site 26
S282
Q
Q
L
G
V
T
L
S
M
T
R
T
E
L
S
Site 27
T286
V
T
L
S
M
T
R
T
E
L
S
P
A
Q
I
Site 28
S289
S
M
T
R
T
E
L
S
P
A
Q
I
K
Q
L
Site 29
S319
A
K
V
D
N
P
D
S
E
K
L
I
P
V
P
Site 30
S355
Q
T
R
L
D
I
I
S
E
D
I
S
E
L
Q
Site 31
S359
D
I
I
S
E
D
I
S
E
L
Q
K
N
Q
T
Site 32
T366
S
E
L
Q
K
N
Q
T
T
S
V
A
K
I
A
Site 33
S368
L
Q
K
N
Q
T
T
S
V
A
K
I
A
Q
Y
Site 34
Y375
S
V
A
K
I
A
Q
Y
K
R
K
L
M
D
L
Site 35
S383
K
R
K
L
M
D
L
S
H
R
T
L
Q
V
L
Site 36
S399
K
Q
E
I
Q
R
K
S
G
Y
A
I
Q
A
D
Site 37
T416
Q
L
R
V
Q
L
D
T
I
Q
G
E
L
N
A
Site 38
S436
G
R
L
N
E
L
M
S
Q
I
R
M
Q
N
H
Site 39
S449
N
H
F
G
A
V
R
S
E
E
R
Y
Y
I
D
Site 40
Y453
A
V
R
S
E
E
R
Y
Y
I
D
A
D
L
L
Site 41
Y454
V
R
S
E
E
R
Y
Y
I
D
A
D
L
L
R
Site 42
S475
K
Q
Q
Q
E
G
L
S
H
L
I
S
I
I
K
Site 43
S479
E
G
L
S
H
L
I
S
I
I
K
D
D
L
E
Site 44
S507
H
I
R
G
G
V
F
S
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation