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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MON2
Full Name:
Protein MON2 homolog
Alias:
KIAA1040, SF21; Protein SF21
Type:
Vesicle trafficking protein
Mass (Da):
190487
Number AA:
1718
UniProt ID:
Q7Z3U7
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006895
GO:0015031
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T4
_
_
_
_
M
S
G
T
S
S
P
E
A
V
K
Site 2
S5
_
_
_
M
S
G
T
S
S
P
E
A
V
K
K
Site 3
S6
_
_
M
S
G
T
S
S
P
E
A
V
K
K
L
Site 4
S19
K
L
L
E
N
M
Q
S
D
L
R
A
L
S
L
Site 5
S25
Q
S
D
L
R
A
L
S
L
E
C
K
K
K
F
Site 6
T48
S
G
I
I
K
V
K
T
I
A
A
R
N
T
E
Site 7
T77
P
F
L
M
G
C
G
T
K
E
P
K
I
T
Q
Site 8
S95
A
A
I
Q
R
L
M
S
H
E
V
V
S
E
T
Site 9
S201
P
V
L
V
Q
G
N
S
N
R
R
S
V
S
T
Site 10
S205
Q
G
N
S
N
R
R
S
V
S
T
L
K
P
C
Site 11
S207
N
S
N
R
R
S
V
S
T
L
K
P
C
A
K
Site 12
T208
S
N
R
R
S
V
S
T
L
K
P
C
A
K
D
Site 13
Y217
K
P
C
A
K
D
A
Y
M
L
F
Q
D
L
C
Site 14
T244
G
M
T
E
M
T
R
T
F
G
L
E
L
L
E
Site 15
S268
F
L
Q
H
Q
E
F
S
F
L
L
K
E
R
V
Site 16
S293
N
I
K
F
R
Q
G
S
S
T
S
S
S
P
A
Site 17
S294
I
K
F
R
Q
G
S
S
T
S
S
S
P
A
P
Site 18
T295
K
F
R
Q
G
S
S
T
S
S
S
P
A
P
V
Site 19
S296
F
R
Q
G
S
S
T
S
S
S
P
A
P
V
E
Site 20
S297
R
Q
G
S
S
T
S
S
S
P
A
P
V
E
K
Site 21
S298
Q
G
S
S
T
S
S
S
P
A
P
V
E
K
P
Site 22
S371
V
Q
P
Q
L
L
R
S
F
C
Q
S
Y
D
M
Site 23
S375
L
L
R
S
F
C
Q
S
Y
D
M
K
Q
H
S
Site 24
Y376
L
R
S
F
C
Q
S
Y
D
M
K
Q
H
S
T
Site 25
T406
S
L
F
L
V
P
P
T
G
N
P
A
T
S
N
Site 26
S423
G
N
N
N
L
G
G
S
V
S
A
P
A
N
S
Site 27
S425
N
N
L
G
G
S
V
S
A
P
A
N
S
G
M
Site 28
Y467
Q
G
S
A
K
A
T
Y
L
E
M
L
D
K
V
Site 29
S486
I
P
E
G
Y
A
M
S
V
A
F
H
C
L
L
Site 30
T517
L
E
T
E
C
Q
T
T
T
E
E
G
S
S
P
Site 31
T518
E
T
E
C
Q
T
T
T
E
E
G
S
S
P
T
Site 32
S523
T
T
T
E
E
G
S
S
P
T
Q
S
T
E
Q
Site 33
S527
E
G
S
S
P
T
Q
S
T
E
Q
Q
D
L
Q
Site 34
S535
T
E
Q
Q
D
L
Q
S
T
S
D
Q
M
D
K
Site 35
S537
Q
Q
D
L
Q
S
T
S
D
Q
M
D
K
E
I
Site 36
S566
C
G
L
L
A
A
L
S
L
L
L
D
A
S
T
Site 37
T573
S
L
L
L
D
A
S
T
D
E
A
A
T
E
N
Site 38
Y617
K
G
S
L
P
P
H
Y
A
L
T
V
L
N
T
Site 39
T629
L
N
T
T
T
A
A
T
L
S
N
K
S
Y
S
Site 40
S631
T
T
T
A
A
T
L
S
N
K
S
Y
S
V
Q
Site 41
S634
A
A
T
L
S
N
K
S
Y
S
V
Q
G
Q
S
Site 42
Y635
A
T
L
S
N
K
S
Y
S
V
Q
G
Q
S
V
Site 43
S636
T
L
S
N
K
S
Y
S
V
Q
G
Q
S
V
M
Site 44
S641
S
Y
S
V
Q
G
Q
S
V
M
M
I
S
P
S
Site 45
S646
G
Q
S
V
M
M
I
S
P
S
S
E
S
H
Q
Site 46
S648
S
V
M
M
I
S
P
S
S
E
S
H
Q
Q
V
Site 47
S649
V
M
M
I
S
P
S
S
E
S
H
Q
Q
V
V
Site 48
S756
I
L
S
R
L
F
E
S
S
Q
Y
L
D
D
V
Site 49
S757
L
S
R
L
F
E
S
S
Q
Y
L
D
D
V
S
Site 50
Y759
R
L
F
E
S
S
Q
Y
L
D
D
V
S
L
H
Site 51
S764
S
Q
Y
L
D
D
V
S
L
H
H
L
I
N
A
Site 52
S774
H
L
I
N
A
L
C
S
L
S
L
E
A
M
D
Site 53
Y784
L
E
A
M
D
M
A
Y
G
N
N
K
E
P
S
Site 54
T849
S
L
I
K
A
G
L
T
F
N
H
D
P
P
L
Site 55
S857
F
N
H
D
P
P
L
S
Q
N
Q
R
L
Q
L
Site 56
S899
I
L
Q
S
Q
G
D
S
L
G
P
G
W
P
L
Site 57
S921
I
R
N
D
Q
G
E
S
L
I
R
T
A
F
Q
Site 58
Y979
L
L
W
N
I
S
D
Y
F
F
Q
R
G
E
T
Site 59
T986
Y
F
F
Q
R
G
E
T
I
E
K
E
L
N
K
Site 60
S1044
P
R
P
A
V
R
K
S
A
G
Q
T
L
F
S
Site 61
T1058
S
T
I
G
A
H
G
T
L
L
Q
H
S
T
W
Site 62
S1083
L
L
D
R
V
R
E
S
S
T
T
A
D
K
E
Site 63
S1084
L
D
R
V
R
E
S
S
T
T
A
D
K
E
K
Site 64
T1086
R
V
R
E
S
S
T
T
A
D
K
E
K
I
E
Site 65
T1107
L
I
H
H
S
R
D
T
A
E
K
Q
W
A
E
Site 66
T1129
G
V
A
R
I
F
N
T
R
R
Y
L
L
Q
P
Site 67
Y1132
R
I
F
N
T
R
R
Y
L
L
Q
P
L
G
D
Site 68
S1153
V
L
L
D
H
I
Q
S
A
A
L
S
K
N
N
Site 69
S1157
H
I
Q
S
A
A
L
S
K
N
N
E
V
S
L
Site 70
S1163
L
S
K
N
N
E
V
S
L
A
A
L
K
S
F
Site 71
S1178
Q
E
I
L
Q
I
V
S
P
V
R
D
S
D
K
Site 72
S1183
I
V
S
P
V
R
D
S
D
K
P
E
T
P
P
Site 73
T1188
R
D
S
D
K
P
E
T
P
P
V
V
N
V
P
Site 74
S1207
I
G
P
I
S
G
M
S
R
P
F
V
R
T
D
Site 75
T1213
M
S
R
P
F
V
R
T
D
S
I
G
E
K
L
Site 76
S1215
R
P
F
V
R
T
D
S
I
G
E
K
L
G
R
Site 77
Y1223
I
G
E
K
L
G
R
Y
S
S
S
E
P
P
I
Site 78
S1224
G
E
K
L
G
R
Y
S
S
S
E
P
P
I
V
Site 79
S1225
E
K
L
G
R
Y
S
S
S
E
P
P
I
V
T
Site 80
S1226
K
L
G
R
Y
S
S
S
E
P
P
I
V
T
D
Site 81
S1253
N
T
W
Y
R
I
G
S
E
S
T
K
P
P
I
Site 82
S1255
W
Y
R
I
G
S
E
S
T
K
P
P
I
T
F
Site 83
T1261
E
S
T
K
P
P
I
T
F
D
K
L
T
F
I
Site 84
Y1358
P
E
N
M
Q
I
M
Y
P
A
I
F
D
Q
L
Site 85
Y1378
F
S
C
K
P
P
Q
Y
G
Q
L
E
T
K
H
Site 86
Y1391
K
H
I
A
N
A
K
Y
N
Q
I
Q
L
F
A
Site 87
Y1407
A
E
W
V
A
L
N
Y
V
P
F
A
E
R
S
Site 88
S1449
K
T
L
R
V
P
L
S
L
K
Y
S
C
P
S
Site 89
Y1452
R
V
P
L
S
L
K
Y
S
C
P
S
E
S
T
Site 90
S1453
V
P
L
S
L
K
Y
S
C
P
S
E
S
T
W
Site 91
S1458
K
Y
S
C
P
S
E
S
T
W
K
L
A
V
S
Site 92
S1466
T
W
K
L
A
V
S
S
L
L
R
V
L
S
I
Site 93
S1483
P
V
A
R
Q
H
A
S
S
G
K
F
D
S
M
Site 94
S1484
V
A
R
Q
H
A
S
S
G
K
F
D
S
M
W
Site 95
S1489
A
S
S
G
K
F
D
S
M
W
P
E
L
A
N
Site 96
S1506
E
D
F
L
F
T
K
S
I
P
P
D
N
L
S
Site 97
S1513
S
I
P
P
D
N
L
S
I
Q
E
F
Q
R
N
Site 98
Y1538
I
S
N
E
I
L
P
Y
A
N
F
I
P
K
E
Site 99
S1558
M
T
M
L
N
K
G
S
I
H
S
Q
S
S
S
Site 100
S1561
L
N
K
G
S
I
H
S
Q
S
S
S
F
T
E
Site 101
S1563
K
G
S
I
H
S
Q
S
S
S
F
T
E
A
E
Site 102
S1565
S
I
H
S
Q
S
S
S
F
T
E
A
E
I
D
Site 103
T1567
H
S
Q
S
S
S
F
T
E
A
E
I
D
I
R
Site 104
S1580
I
R
L
R
E
E
F
S
K
M
C
F
E
T
L
Site 105
S1591
F
E
T
L
L
Q
F
S
F
S
N
K
V
T
T
Site 106
S1593
T
L
L
Q
F
S
F
S
N
K
V
T
T
P
Q
Site 107
T1597
F
S
F
S
N
K
V
T
T
P
Q
E
G
Y
I
Site 108
T1598
S
F
S
N
K
V
T
T
P
Q
E
G
Y
I
S
Site 109
Y1603
V
T
T
P
Q
E
G
Y
I
S
R
M
A
L
S
Site 110
S1616
L
S
V
L
L
K
R
S
Q
D
V
L
H
R
Y
Site 111
Y1623
S
Q
D
V
L
H
R
Y
I
E
D
E
R
L
S
Site 112
S1630
Y
I
E
D
E
R
L
S
G
K
C
P
L
P
R
Site 113
T1652
F
V
L
K
A
V
S
T
L
I
D
S
L
K
K
Site 114
S1656
A
V
S
T
L
I
D
S
L
K
K
T
Q
P
E
Site 115
T1660
L
I
D
S
L
K
K
T
Q
P
E
N
V
D
G
Site 116
S1711
D
F
M
Q
P
P
A
S
R
V
Q
N
G
E
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation