KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
NUFIP2
Full Name:
Nuclear fragile X mental retardation-interacting protein 2
Alias:
182-FIP; 82-FIP; FIP-82; FMRP interacting protein, 82kD; FMRP-interacting protein 2; KIAA1321; MGC117262; Nuclear fragile X mental retardation protein interacting protein 2; NUFP2; PIG1
Type:
RNA binding protein, RNA processing
Mass (Da):
76121
Number AA:
695
UniProt ID:
Q7Z417
International Prot ID:
IPI00002349
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005634
GO:0042788
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0005515
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y57
H
H
Q
Q
P
H
Q
Y
L
Q
H
G
A
E
G
Site 2
S65
L
Q
H
G
A
E
G
S
P
K
A
Q
P
K
P
Site 3
T80
L
K
H
E
Q
K
H
T
L
Q
Q
H
Q
E
T
Site 4
T87
T
L
Q
Q
H
Q
E
T
P
K
K
K
T
G
Y
Site 5
Y94
T
P
K
K
K
T
G
Y
G
E
L
N
G
N
A
Site 6
S107
N
A
G
E
R
E
I
S
L
K
N
L
S
S
D
Site 7
S112
E
I
S
L
K
N
L
S
S
D
E
A
T
N
P
Site 8
S113
I
S
L
K
N
L
S
S
D
E
A
T
N
P
I
Site 9
T117
N
L
S
S
D
E
A
T
N
P
I
S
R
V
L
Site 10
S121
D
E
A
T
N
P
I
S
R
V
L
N
G
N
Q
Site 11
S134
N
Q
Q
V
V
D
T
S
L
K
Q
T
V
K
A
Site 12
T138
V
D
T
S
L
K
Q
T
V
K
A
N
T
F
G
Site 13
T143
K
Q
T
V
K
A
N
T
F
G
K
A
G
I
K
Site 14
S167
M
D
K
K
N
G
K
S
Y
E
N
K
S
G
E
Site 15
Y168
D
K
K
N
G
K
S
Y
E
N
K
S
G
E
N
Site 16
S172
G
K
S
Y
E
N
K
S
G
E
N
Q
S
V
D
Site 17
S177
N
K
S
G
E
N
Q
S
V
D
K
S
D
T
I
Site 18
S181
E
N
Q
S
V
D
K
S
D
T
I
P
I
P
N
Site 19
T183
Q
S
V
D
K
S
D
T
I
P
I
P
N
G
V
Site 20
Y197
V
V
T
N
N
S
G
Y
I
T
N
G
Y
M
G
Site 21
T199
T
N
N
S
G
Y
I
T
N
G
Y
M
G
K
G
Site 22
Y202
S
G
Y
I
T
N
G
Y
M
G
K
G
A
D
N
Site 23
S212
K
G
A
D
N
D
G
S
G
S
E
S
G
Y
T
Site 24
S214
A
D
N
D
G
S
G
S
E
S
G
Y
T
T
P
Site 25
S216
N
D
G
S
G
S
E
S
G
Y
T
T
P
K
K
Site 26
Y218
G
S
G
S
E
S
G
Y
T
T
P
K
K
R
K
Site 27
T219
S
G
S
E
S
G
Y
T
T
P
K
K
R
K
A
Site 28
T220
G
S
E
S
G
Y
T
T
P
K
K
R
K
A
R
Site 29
S230
K
R
K
A
R
R
N
S
A
K
G
C
E
N
L
Site 30
S250
K
I
M
Q
Q
E
T
S
V
P
T
L
K
Q
G
Site 31
T260
T
L
K
Q
G
L
E
T
F
K
P
D
Y
S
E
Site 32
Y265
L
E
T
F
K
P
D
Y
S
E
Q
K
G
N
R
Site 33
S266
E
T
F
K
P
D
Y
S
E
Q
K
G
N
R
V
Site 34
S276
K
G
N
R
V
D
G
S
K
P
I
W
K
Y
E
Site 35
Y282
G
S
K
P
I
W
K
Y
E
T
G
P
G
G
T
Site 36
S303
V
G
D
M
L
R
K
S
S
D
S
K
P
G
V
Site 37
S304
G
D
M
L
R
K
S
S
D
S
K
P
G
V
S
Site 38
S306
M
L
R
K
S
S
D
S
K
P
G
V
S
S
K
Site 39
S311
S
D
S
K
P
G
V
S
S
K
K
F
D
D
R
Site 40
S312
D
S
K
P
G
V
S
S
K
K
F
D
D
R
P
Site 41
S325
R
P
K
G
K
H
A
S
A
V
A
S
K
E
D
Site 42
S329
K
H
A
S
A
V
A
S
K
E
D
S
W
T
L
Site 43
S333
A
V
A
S
K
E
D
S
W
T
L
F
K
P
P
Site 44
T335
A
S
K
E
D
S
W
T
L
F
K
P
P
P
V
Site 45
S348
P
V
F
P
V
D
N
S
S
A
K
I
V
P
K
Site 46
T369
V
K
E
N
L
N
K
T
I
Q
N
S
S
V
S
Site 47
S373
L
N
K
T
I
Q
N
S
S
V
S
P
T
S
S
Site 48
S374
N
K
T
I
Q
N
S
S
V
S
P
T
S
S
S
Site 49
S376
T
I
Q
N
S
S
V
S
P
T
S
S
S
S
S
Site 50
T378
Q
N
S
S
V
S
P
T
S
S
S
S
S
S
S
Site 51
S379
N
S
S
V
S
P
T
S
S
S
S
S
S
S
S
Site 52
S380
S
S
V
S
P
T
S
S
S
S
S
S
S
S
T
Site 53
S381
S
V
S
P
T
S
S
S
S
S
S
S
S
T
G
Site 54
S382
V
S
P
T
S
S
S
S
S
S
S
S
T
G
E
Site 55
S383
S
P
T
S
S
S
S
S
S
S
S
T
G
E
T
Site 56
S384
P
T
S
S
S
S
S
S
S
S
T
G
E
T
Q
Site 57
S385
T
S
S
S
S
S
S
S
S
T
G
E
T
Q
T
Site 58
S386
S
S
S
S
S
S
S
S
T
G
E
T
Q
T
Q
Site 59
T387
S
S
S
S
S
S
S
T
G
E
T
Q
T
Q
S
Site 60
T390
S
S
S
S
T
G
E
T
Q
T
Q
S
S
S
R
Site 61
T392
S
S
T
G
E
T
Q
T
Q
S
S
S
R
L
S
Site 62
S394
T
G
E
T
Q
T
Q
S
S
S
R
L
S
Q
V
Site 63
S395
G
E
T
Q
T
Q
S
S
S
R
L
S
Q
V
P
Site 64
S396
E
T
Q
T
Q
S
S
S
R
L
S
Q
V
P
M
Site 65
S399
T
Q
S
S
S
R
L
S
Q
V
P
M
S
A
L
Site 66
S404
R
L
S
Q
V
P
M
S
A
L
K
S
V
T
S
Site 67
S411
S
A
L
K
S
V
T
S
A
N
F
S
N
G
P
Site 68
Y428
A
G
T
D
G
N
V
Y
P
P
G
G
Q
P
L
Site 69
T444
T
T
A
A
N
T
L
T
P
I
S
S
G
T
D
Site 70
S448
N
T
L
T
P
I
S
S
G
T
D
S
V
L
Q
Site 71
S452
P
I
S
S
G
T
D
S
V
L
Q
D
M
S
L
Site 72
S470
A
V
E
Q
I
K
T
S
L
F
I
Y
P
S
N
Site 73
T480
I
Y
P
S
N
M
Q
T
M
L
L
S
T
A
Q
Site 74
S492
T
A
Q
V
D
L
P
S
Q
T
D
Q
Q
N
L
Site 75
S510
F
Q
N
Q
W
G
L
S
F
I
N
E
P
S
A
Site 76
T521
E
P
S
A
G
P
E
T
V
T
G
K
S
S
E
Site 77
T523
S
A
G
P
E
T
V
T
G
K
S
S
E
H
K
Site 78
S526
P
E
T
V
T
G
K
S
S
E
H
K
V
M
E
Site 79
T535
E
H
K
V
M
E
V
T
F
Q
G
E
Y
P
A
Site 80
Y540
E
V
T
F
Q
G
E
Y
P
A
T
L
V
S
Q
Site 81
T543
F
Q
G
E
Y
P
A
T
L
V
S
Q
G
A
E
Site 82
S554
Q
G
A
E
I
I
P
S
G
T
E
H
P
V
F
Site 83
T556
A
E
I
I
P
S
G
T
E
H
P
V
F
P
K
Site 84
T571
A
Y
E
L
E
K
R
T
S
P
Q
V
L
G
S
Site 85
S572
Y
E
L
E
K
R
T
S
P
Q
V
L
G
S
I
Site 86
S578
T
S
P
Q
V
L
G
S
I
L
K
S
G
T
T
Site 87
S582
V
L
G
S
I
L
K
S
G
T
T
S
E
S
G
Site 88
T584
G
S
I
L
K
S
G
T
T
S
E
S
G
A
L
Site 89
S588
K
S
G
T
T
S
E
S
G
A
L
S
L
E
P
Site 90
S592
T
S
E
S
G
A
L
S
L
E
P
S
H
I
G
Site 91
S596
G
A
L
S
L
E
P
S
H
I
G
D
L
Q
K
Site 92
T606
G
D
L
Q
K
A
D
T
S
S
Q
G
A
L
V
Site 93
S608
L
Q
K
A
D
T
S
S
Q
G
A
L
V
F
L
Site 94
Y619
L
V
F
L
S
K
D
Y
E
I
E
S
Q
N
P
Site 95
S623
S
K
D
Y
E
I
E
S
Q
N
P
L
A
S
P
Site 96
S629
E
S
Q
N
P
L
A
S
P
T
N
T
L
L
G
Site 97
T631
Q
N
P
L
A
S
P
T
N
T
L
L
G
S
A
Site 98
T633
P
L
A
S
P
T
N
T
L
L
G
S
A
K
E
Site 99
S637
P
T
N
T
L
L
G
S
A
K
E
Q
R
Y
Q
Site 100
Y643
G
S
A
K
E
Q
R
Y
Q
R
G
L
E
R
N
Site 101
S652
R
G
L
E
R
N
D
S
W
G
S
F
D
L
R
Site 102
S655
E
R
N
D
S
W
G
S
F
D
L
R
A
A
I
Site 103
Y664
D
L
R
A
A
I
V
Y
H
T
K
E
M
E
S
Site 104
T685
Q
D
P
K
R
I
I
T
Y
N
E
A
M
D
S
Site 105
S692
T
Y
N
E
A
M
D
S
P
D
Q
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation