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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MDS024
Full Name:
tRNA guanosine-2'-O-methyltransferase TRM11 homolog
Alias:
C6orf75; EC 2.1.1.-; RNA methylase; TRM11
Type:
RNA binding protein, methyltransferase
Mass (Da):
53421
Number AA:
463
UniProt ID:
Q7Z4G4
International Prot ID:
IPI00470606
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0008168
GO:0003676
PhosphoSite+
KinaseNET
Biological Process:
GO:0032259
GO:0008033
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S39
L
F
G
G
Q
F
A
S
S
Q
E
T
Y
G
K
Site 2
S40
F
G
G
Q
F
A
S
S
Q
E
T
Y
G
K
S
Site 3
T43
Q
F
A
S
S
Q
E
T
Y
G
K
S
P
F
W
Site 4
Y44
F
A
S
S
Q
E
T
Y
G
K
S
P
F
W
I
Site 5
S47
S
Q
E
T
Y
G
K
S
P
F
W
I
L
S
I
Site 6
S82
E
L
W
G
H
G
Q
S
P
E
E
L
Y
S
S
Site 7
Y87
G
Q
S
P
E
E
L
Y
S
S
L
K
N
Y
P
Site 8
S88
Q
S
P
E
E
L
Y
S
S
L
K
N
Y
P
V
Site 9
S89
S
P
E
E
L
Y
S
S
L
K
N
Y
P
V
E
Site 10
Y93
L
Y
S
S
L
K
N
Y
P
V
E
K
M
V
P
Site 11
S106
V
P
F
L
H
S
D
S
T
Y
K
I
K
I
H
Site 12
T107
P
F
L
H
S
D
S
T
Y
K
I
K
I
H
T
Site 13
Y108
F
L
H
S
D
S
T
Y
K
I
K
I
H
T
F
Site 14
T114
T
Y
K
I
K
I
H
T
F
N
K
T
L
T
Q
Site 15
T118
K
I
H
T
F
N
K
T
L
T
Q
E
E
K
I
Site 16
Y170
P
E
N
P
H
N
I
Y
F
G
R
W
I
A
D
Site 17
S185
G
Q
R
E
L
I
E
S
Y
S
V
K
K
R
H
Site 18
Y186
Q
R
E
L
I
E
S
Y
S
V
K
K
R
H
F
Site 19
S187
R
E
L
I
E
S
Y
S
V
K
K
R
H
F
I
Site 20
Y247
V
Y
G
T
D
I
D
Y
N
T
V
H
G
L
G
Site 21
T249
G
T
D
I
D
Y
N
T
V
H
G
L
G
K
A
Site 22
Y277
I
R
A
N
L
R
Q
Y
G
L
E
K
Y
Y
L
Site 23
Y282
R
Q
Y
G
L
E
K
Y
Y
L
D
V
L
V
S
Site 24
Y283
Q
Y
G
L
E
K
Y
Y
L
D
V
L
V
S
D
Site 25
S289
Y
Y
L
D
V
L
V
S
D
A
S
K
P
S
W
Site 26
S292
D
V
L
V
S
D
A
S
K
P
S
W
R
K
G
Site 27
S295
V
S
D
A
S
K
P
S
W
R
K
G
T
Y
F
Site 28
T300
K
P
S
W
R
K
G
T
Y
F
D
A
I
I
T
Site 29
Y301
P
S
W
R
K
G
T
Y
F
D
A
I
I
T
D
Site 30
T307
T
Y
F
D
A
I
I
T
D
P
P
Y
G
I
R
Site 31
Y311
A
I
I
T
D
P
P
Y
G
I
R
E
S
T
R
Site 32
S316
P
P
Y
G
I
R
E
S
T
R
R
T
G
S
Q
Site 33
T317
P
Y
G
I
R
E
S
T
R
R
T
G
S
Q
K
Site 34
T320
I
R
E
S
T
R
R
T
G
S
Q
K
E
I
P
Site 35
S322
E
S
T
R
R
T
G
S
Q
K
E
I
P
K
G
Site 36
S339
K
W
E
K
C
P
E
S
H
V
P
V
S
L
S
Site 37
S344
P
E
S
H
V
P
V
S
L
S
Y
H
L
S
D
Site 38
Y377
L
V
Y
W
L
P
V
Y
T
P
E
Y
T
E
E
Site 39
T378
V
Y
W
L
P
V
Y
T
P
E
Y
T
E
E
M
Site 40
Y381
L
P
V
Y
T
P
E
Y
T
E
E
M
V
P
W
Site 41
S403
S
N
C
E
Q
K
L
S
S
H
T
S
R
R
L
Site 42
T406
E
Q
K
L
S
S
H
T
S
R
R
L
I
T
M
Site 43
S407
Q
K
L
S
S
H
T
S
R
R
L
I
T
M
E
Site 44
T412
H
T
S
R
R
L
I
T
M
E
K
V
K
K
F
Site 45
Y425
K
F
E
N
R
D
Q
Y
S
H
L
L
S
D
H
Site 46
S426
F
E
N
R
D
Q
Y
S
H
L
L
S
D
H
F
Site 47
S430
D
Q
Y
S
H
L
L
S
D
H
F
L
P
Y
Q
Site 48
Y436
L
S
D
H
F
L
P
Y
Q
G
H
N
S
F
R
Site 49
S441
L
P
Y
Q
G
H
N
S
F
R
E
K
Y
F
S
Site 50
Y446
H
N
S
F
R
E
K
Y
F
S
G
V
T
K
R
Site 51
S448
S
F
R
E
K
Y
F
S
G
V
T
K
R
I
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation