KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
HAUS6
Full Name:
HAUS augmin-like complex subunit 6
Alias:
Dgt6; FA29A; FAM29A; FLJ20060; HAUS augmin-like complex, subunit 6; KIAA1574; MGC102696; RP11-296P7.3
Type:
Unknown function
Mass (Da):
108621
Number AA:
955
UniProt ID:
Q7Z4H7
International Prot ID:
IPI00719210
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
S
S
A
S
V
T
A
F
E
K
E
H
L
Site 2
Y17
E
K
E
H
L
W
M
Y
L
Q
A
L
G
F
E
Site 3
S68
L
F
Q
V
L
D
Q
S
L
T
K
E
V
F
K
Site 4
T70
Q
V
L
D
Q
S
L
T
K
E
V
F
K
F
C
Site 5
S85
W
P
P
F
D
Q
K
S
D
T
E
F
R
K
H
Site 6
T87
P
F
D
Q
K
S
D
T
E
F
R
K
H
C
C
Site 7
S106
R
I
S
G
E
C
G
S
S
F
P
Q
V
V
G
Site 8
Y139
A
R
F
V
A
M
K
Y
I
K
S
N
S
K
N
Site 9
S142
V
A
M
K
Y
I
K
S
N
S
K
N
S
S
H
Site 10
S144
M
K
Y
I
K
S
N
S
K
N
S
S
H
H
F
Site 11
S148
K
S
N
S
K
N
S
S
H
H
F
V
E
T
F
Site 12
T154
S
S
H
H
F
V
E
T
F
N
I
K
P
Q
D
Site 13
T187
L
Q
R
Q
D
C
V
T
Q
K
Y
Q
E
N
A
Site 14
Y190
Q
D
C
V
T
Q
K
Y
Q
E
N
A
Q
L
S
Site 15
S206
K
Q
V
R
N
L
R
S
E
C
I
G
L
E
N
Site 16
Y221
Q
I
K
K
M
E
P
Y
D
D
H
S
N
M
E
Site 17
S236
E
K
I
Q
K
V
R
S
L
W
A
S
V
N
E
Site 18
S256
E
K
E
R
E
V
V
S
S
V
L
S
L
V
N
Site 19
S257
K
E
R
E
V
V
S
S
V
L
S
L
V
N
Q
Site 20
Y297
Q
L
H
I
G
N
V
Y
E
A
G
K
L
N
L
Site 21
Y320
E
V
L
K
V
M
K
Y
E
R
C
Q
A
D
Q
Site 22
T331
Q
A
D
Q
A
R
L
T
V
D
L
H
Y
L
E
Site 23
Y336
R
L
T
V
D
L
H
Y
L
E
K
E
T
K
F
Site 24
S349
K
F
Q
K
E
R
L
S
D
L
K
H
M
R
Y
Site 25
T363
Y
R
I
K
D
D
L
T
T
I
R
H
S
V
V
Site 26
T364
R
I
K
D
D
L
T
T
I
R
H
S
V
V
E
Site 27
S368
D
L
T
T
I
R
H
S
V
V
E
K
Q
G
E
Site 28
S387
W
K
E
F
L
G
L
S
P
F
S
L
I
K
G
Site 29
S406
V
D
L
L
P
P
M
S
P
L
S
F
D
P
A
Site 30
S409
L
P
P
M
S
P
L
S
F
D
P
A
S
E
E
Site 31
S414
P
L
S
F
D
P
A
S
E
E
V
Y
A
K
S
Site 32
Y418
D
P
A
S
E
E
V
Y
A
K
S
I
L
C
Q
Site 33
S421
S
E
E
V
Y
A
K
S
I
L
C
Q
Y
P
A
Site 34
S429
I
L
C
Q
Y
P
A
S
L
P
D
A
H
K
Q
Site 35
S447
E
N
G
C
R
G
D
S
D
T
L
G
A
L
H
Site 36
T449
G
C
R
G
D
S
D
T
L
G
A
L
H
D
L
Site 37
S459
A
L
H
D
L
A
N
S
P
A
S
F
L
S
Q
Site 38
S462
D
L
A
N
S
P
A
S
F
L
S
Q
S
V
S
Site 39
S465
N
S
P
A
S
F
L
S
Q
S
V
S
S
S
D
Site 40
S467
P
A
S
F
L
S
Q
S
V
S
S
S
D
R
N
Site 41
S469
S
F
L
S
Q
S
V
S
S
S
D
R
N
S
V
Site 42
S471
L
S
Q
S
V
S
S
S
D
R
N
S
V
T
V
Site 43
S475
V
S
S
S
D
R
N
S
V
T
V
L
E
K
D
Site 44
T477
S
S
D
R
N
S
V
T
V
L
E
K
D
T
K
Site 45
T483
V
T
V
L
E
K
D
T
K
M
G
T
P
K
E
Site 46
T487
E
K
D
T
K
M
G
T
P
K
E
K
N
E
A
Site 47
S507
P
E
F
E
V
E
N
S
P
L
S
D
V
A
K
Site 48
S510
E
V
E
N
S
P
L
S
D
V
A
K
N
T
E
Site 49
S519
V
A
K
N
T
E
S
S
A
F
G
G
S
L
P
Site 50
S524
E
S
S
A
F
G
G
S
L
P
A
K
K
S
D
Site 51
S530
G
S
L
P
A
K
K
S
D
P
F
Q
K
E
Q
Site 52
S550
E
V
A
R
A
V
L
S
D
S
P
Q
L
S
E
Site 53
S552
A
R
A
V
L
S
D
S
P
Q
L
S
E
G
K
Site 54
S556
L
S
D
S
P
Q
L
S
E
G
K
E
I
K
L
Site 55
S569
K
L
E
E
L
I
D
S
L
G
S
N
P
F
L
Site 56
T577
L
G
S
N
P
F
L
T
R
N
Q
I
P
R
T
Site 57
T584
T
R
N
Q
I
P
R
T
P
E
N
L
I
T
E
Site 58
T590
R
T
P
E
N
L
I
T
E
I
R
S
S
W
R
Site 59
S595
L
I
T
E
I
R
S
S
W
R
K
A
I
E
M
Site 60
T607
I
E
M
E
E
N
R
T
K
E
P
I
Q
M
D
Site 61
S624
H
R
E
V
L
P
E
S
L
P
V
L
H
N
Q
Site 62
S635
L
H
N
Q
R
E
F
S
M
A
D
F
L
L
E
Site 63
T644
A
D
F
L
L
E
T
T
V
S
D
F
G
Q
S
Site 64
S646
F
L
L
E
T
T
V
S
D
F
G
Q
S
H
L
Site 65
T654
D
F
G
Q
S
H
L
T
E
E
K
V
I
S
D
Site 66
S660
L
T
E
E
K
V
I
S
D
C
E
C
V
P
Q
Site 67
T672
V
P
Q
K
H
V
L
T
S
H
I
D
E
P
P
Site 68
T680
S
H
I
D
E
P
P
T
Q
N
Q
S
D
L
L
Site 69
S706
C
L
A
F
T
K
L
S
E
T
S
R
M
E
T
Site 70
T708
A
F
T
K
L
S
E
T
S
R
M
E
T
F
S
Site 71
T713
S
E
T
S
R
M
E
T
F
S
P
A
V
G
N
Site 72
S715
T
S
R
M
E
T
F
S
P
A
V
G
N
R
I
Site 73
S728
R
I
D
V
M
G
G
S
E
E
E
F
M
K
I
Site 74
S742
I
L
D
H
L
E
V
S
C
N
K
P
S
T
N
Site 75
S760
L
W
N
S
F
Q
I
S
S
G
I
S
S
K
S
Site 76
S761
W
N
S
F
Q
I
S
S
G
I
S
S
K
S
F
Site 77
S764
F
Q
I
S
S
G
I
S
S
K
S
F
K
D
N
Site 78
S765
Q
I
S
S
G
I
S
S
K
S
F
K
D
N
D
Site 79
S767
S
S
G
I
S
S
K
S
F
K
D
N
D
F
G
Site 80
S788
P
E
E
V
G
H
L
S
F
N
S
S
S
S
S
Site 81
S791
V
G
H
L
S
F
N
S
S
S
S
S
E
A
N
Site 82
S792
G
H
L
S
F
N
S
S
S
S
S
E
A
N
F
Site 83
S793
H
L
S
F
N
S
S
S
S
S
E
A
N
F
K
Site 84
S795
S
F
N
S
S
S
S
S
E
A
N
F
K
L
E
Site 85
S805
N
F
K
L
E
P
N
S
P
M
H
G
G
T
L
Site 86
T811
N
S
P
M
H
G
G
T
L
L
E
D
V
V
G
Site 87
T822
D
V
V
G
G
R
Q
T
T
P
E
S
D
F
N
Site 88
T823
V
V
G
G
R
Q
T
T
P
E
S
D
F
N
L
Site 89
S826
G
R
Q
T
T
P
E
S
D
F
N
L
Q
A
L
Site 90
S835
F
N
L
Q
A
L
R
S
R
Y
E
A
L
K
K
Site 91
Y837
L
Q
A
L
R
S
R
Y
E
A
L
K
K
S
L
Site 92
S843
R
Y
E
A
L
K
K
S
L
S
K
K
R
E
E
Site 93
S845
E
A
L
K
K
S
L
S
K
K
R
E
E
S
Y
Site 94
S851
L
S
K
K
R
E
E
S
Y
L
S
N
S
Q
T
Site 95
Y852
S
K
K
R
E
E
S
Y
L
S
N
S
Q
T
P
Site 96
S854
K
R
E
E
S
Y
L
S
N
S
Q
T
P
E
R
Site 97
S856
E
E
S
Y
L
S
N
S
Q
T
P
E
R
H
K
Site 98
T858
S
Y
L
S
N
S
Q
T
P
E
R
H
K
P
E
Site 99
S867
E
R
H
K
P
E
L
S
P
T
P
Q
N
V
Q
Site 100
T869
H
K
P
E
L
S
P
T
P
Q
N
V
Q
T
D
Site 101
T878
Q
N
V
Q
T
D
D
T
L
N
F
L
D
T
C
Site 102
T889
L
D
T
C
D
L
H
T
E
H
I
K
P
S
L
Site 103
S895
H
T
E
H
I
K
P
S
L
R
T
S
I
G
E
Site 104
S899
I
K
P
S
L
R
T
S
I
G
E
R
K
R
S
Site 105
S906
S
I
G
E
R
K
R
S
L
S
P
L
I
K
F
Site 106
S908
G
E
R
K
R
S
L
S
P
L
I
K
F
S
P
Site 107
S914
L
S
P
L
I
K
F
S
P
V
E
Q
R
L
R
Site 108
T922
P
V
E
Q
R
L
R
T
T
I
A
C
S
L
G
Site 109
T923
V
E
Q
R
L
R
T
T
I
A
C
S
L
G
E
Site 110
S943
E
E
D
I
L
N
K
S
L
D
A
K
E
P
P
Site 111
S951
L
D
A
K
E
P
P
S
D
L
T
R
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation