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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MDGA2
Full Name:
MAM domain-containing glycosylphosphatidylinositol anchor protein 2
Alias:
MAM domain-containing protein 1
Type:
Mass (Da):
107436
Number AA:
956
UniProt ID:
Q7Z553
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T28
Q
G
V
Y
A
P
P
T
V
R
I
V
H
S
G
Site 2
Y45
C
N
I
E
E
E
R
Y
S
E
R
V
Y
T
I
Site 3
S46
N
I
E
E
E
R
Y
S
E
R
V
Y
T
I
R
Site 4
Y50
E
R
Y
S
E
R
V
Y
T
I
R
E
G
E
T
Site 5
T51
R
Y
S
E
R
V
Y
T
I
R
E
G
E
T
L
Site 6
T61
E
G
E
T
L
E
L
T
C
L
V
T
G
H
P
Site 7
T75
P
R
P
Q
I
R
W
T
K
T
A
G
S
A
S
Site 8
T77
P
Q
I
R
W
T
K
T
A
G
S
A
S
D
R
Site 9
S82
T
K
T
A
G
S
A
S
D
R
F
Q
D
S
S
Site 10
S88
A
S
D
R
F
Q
D
S
S
V
F
N
E
T
L
Site 11
S89
S
D
R
F
Q
D
S
S
V
F
N
E
T
L
R
Site 12
Y108
Q
R
H
Q
G
G
R
Y
Y
C
K
A
E
N
G
Site 13
Y109
R
H
Q
G
G
R
Y
Y
C
K
A
E
N
G
L
Site 14
S118
K
A
E
N
G
L
G
S
P
A
I
K
S
I
R
Site 15
Y129
K
S
I
R
V
D
V
Y
Y
L
D
D
P
V
V
Site 16
T137
Y
L
D
D
P
V
V
T
V
H
Q
S
I
G
E
Site 17
Y150
G
E
A
K
E
Q
F
Y
Y
E
R
T
V
F
L
Site 18
Y151
E
A
K
E
Q
F
Y
Y
E
R
T
V
F
L
R
Site 19
S163
F
L
R
C
V
A
N
S
N
P
P
V
R
Y
S
Site 20
S170
S
N
P
P
V
R
Y
S
W
R
R
G
Q
E
V
Site 21
S182
Q
E
V
L
L
Q
G
S
D
K
G
V
E
I
Y
Site 22
Y189
S
D
K
G
V
E
I
Y
E
P
F
F
T
Q
G
Site 23
T194
E
I
Y
E
P
F
F
T
Q
G
E
T
K
I
L
Site 24
Y211
K
N
L
R
P
Q
D
Y
A
N
Y
S
C
I
A
Site 25
Y214
R
P
Q
D
Y
A
N
Y
S
C
I
A
S
V
R
Site 26
S232
N
I
P
D
K
M
V
S
F
R
L
S
N
K
T
Site 27
S236
K
M
V
S
F
R
L
S
N
K
T
A
S
P
S
Site 28
T239
S
F
R
L
S
N
K
T
A
S
P
S
I
K
L
Site 29
S241
R
L
S
N
K
T
A
S
P
S
I
K
L
L
V
Site 30
S243
S
N
K
T
A
S
P
S
I
K
L
L
V
D
D
Site 31
S274
T
G
G
E
P
A
P
S
L
T
W
V
R
S
F
Site 32
T276
G
E
P
A
P
S
L
T
W
V
R
S
F
G
T
Site 33
S280
P
S
L
T
W
V
R
S
F
G
T
L
P
E
K
Site 34
S323
V
G
N
P
A
K
K
S
T
N
I
I
V
R
A
Site 35
T339
K
K
G
R
F
W
I
T
P
D
P
Y
H
K
D
Site 36
S366
C
Q
V
E
A
V
P
S
E
E
L
T
F
S
W
Site 37
T370
A
V
P
S
E
E
L
T
F
S
W
F
K
N
G
Site 38
S372
P
S
E
E
L
T
F
S
W
F
K
N
G
R
P
Site 39
S383
N
G
R
P
L
R
S
S
E
R
M
V
I
T
Q
Site 40
T391
E
R
M
V
I
T
Q
T
D
P
D
V
S
P
G
Site 41
S396
T
Q
T
D
P
D
V
S
P
G
T
T
N
L
D
Site 42
T445
S
T
V
P
P
N
L
T
V
P
Q
E
K
S
P
Site 43
S451
L
T
V
P
Q
E
K
S
P
L
V
T
R
E
G
Site 44
S490
E
V
A
M
P
D
G
S
M
Q
M
E
S
Y
D
Site 45
S495
D
G
S
M
Q
M
E
S
Y
D
G
T
L
R
I
Site 46
T499
Q
M
E
S
Y
D
G
T
L
R
I
V
N
V
S
Site 47
S506
T
L
R
I
V
N
V
S
R
E
M
S
G
M
Y
Site 48
Y513
S
R
E
M
S
G
M
Y
R
C
Q
T
S
Q
Y
Site 49
S556
I
R
Q
G
Q
D
R
S
V
T
M
S
C
R
V
Site 50
T558
Q
G
Q
D
R
S
V
T
M
S
C
R
V
L
R
Site 51
S560
Q
D
R
S
V
T
M
S
C
R
V
L
R
A
Y
Site 52
T573
A
Y
P
I
R
V
L
T
Y
E
W
R
L
G
N
Site 53
Y574
Y
P
I
R
V
L
T
Y
E
W
R
L
G
N
K
Site 54
S590
L
R
T
G
Q
F
D
S
Q
E
Y
T
E
Y
A
Site 55
T594
Q
F
D
S
Q
E
Y
T
E
Y
A
V
K
S
L
Site 56
Y596
D
S
Q
E
Y
T
E
Y
A
V
K
S
L
S
N
Site 57
S600
Y
T
E
Y
A
V
K
S
L
S
N
E
N
Y
G
Site 58
S602
E
Y
A
V
K
S
L
S
N
E
N
Y
G
V
Y
Site 59
Y606
K
S
L
S
N
E
N
Y
G
V
Y
N
C
S
I
Site 60
Y609
S
N
E
N
Y
G
V
Y
N
C
S
I
I
N
E
Site 61
T627
G
R
C
S
F
L
V
T
G
K
A
Y
A
P
E
Site 62
Y637
A
Y
A
P
E
F
Y
Y
D
T
Y
N
P
V
W
Site 63
Y640
P
E
F
Y
Y
D
T
Y
N
P
V
W
Q
N
R
Site 64
Y702
Q
K
G
E
L
I
T
Y
N
L
T
E
L
I
K
Site 65
Y713
E
L
I
K
P
E
A
Y
E
V
R
L
T
P
L
Site 66
T718
E
A
Y
E
V
R
L
T
P
L
T
K
F
G
E
Site 67
T721
E
V
R
L
T
P
L
T
K
F
G
E
G
D
S
Site 68
S728
T
K
F
G
E
G
D
S
T
I
R
V
I
K
Y
Site 69
T729
K
F
G
E
G
D
S
T
I
R
V
I
K
Y
S
Site 70
Y735
S
T
I
R
V
I
K
Y
S
A
P
V
N
P
H
Site 71
T778
Q
S
T
A
T
R
N
T
K
Y
T
P
N
T
G
Site 72
Y780
T
A
T
R
N
T
K
Y
T
P
N
T
G
P
N
Site 73
T781
A
T
R
N
T
K
Y
T
P
N
T
G
P
N
A
Site 74
S791
T
G
P
N
A
D
R
S
G
S
K
E
G
F
Y
Site 75
S793
P
N
A
D
R
S
G
S
K
E
G
F
Y
M
Y
Site 76
Y798
S
G
S
K
E
G
F
Y
M
Y
I
E
T
S
R
Site 77
Y800
S
K
E
G
F
Y
M
Y
I
E
T
S
R
P
R
Site 78
T803
G
F
Y
M
Y
I
E
T
S
R
P
R
L
E
G
Site 79
S821
R
L
L
S
P
V
F
S
I
A
P
K
N
P
Y
Site 80
Y828
S
I
A
P
K
N
P
Y
G
P
T
N
T
A
Y
Site 81
T861
Y
L
R
L
K
G
Q
T
T
I
E
N
P
L
W
Site 82
T862
L
R
L
K
G
Q
T
T
I
E
N
P
L
W
S
Site 83
S871
E
N
P
L
W
S
S
S
G
N
K
G
Q
R
W
Site 84
Y886
N
E
A
H
V
N
I
Y
P
I
T
S
F
Q
L
Site 85
S929
Q
D
L
A
T
K
N
S
V
D
G
A
V
G
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation