KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
BRAP
Full Name:
BRCA1-associated protein
Alias:
BRAP2; BRCA1 associated protein; EC 6.3.2.-; Galectin-2¿¿¿binding protein; IMP; Impedes mitogenic signal propagati; Impedes mitogenic signal propagation; RNF52
Type:
Ligase, Ubiquitin conjugating system, Amino Acid Metabolism group, Tryptophan metabolism family
Mass (Da):
67291
Number AA:
592
UniProt ID:
Q7Z569
International Prot ID:
IPI00396089
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0042802
GO:0004842
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0019941
GO:0009968
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
R
L
E
L
A
E
H
S
P
V
P
A
G
F
G
Site 2
S32
S
A
A
A
G
E
M
S
D
E
E
I
K
K
T
Site 3
T39
S
D
E
E
I
K
K
T
T
L
A
S
A
V
A
Site 4
S52
V
A
C
L
E
G
K
S
P
G
E
K
V
A
I
Site 5
T70
H
L
G
R
R
E
M
T
D
V
I
I
E
T
M
Site 6
S79
V
I
I
E
T
M
K
S
N
P
D
E
L
K
T
Site 7
T86
S
N
P
D
E
L
K
T
T
V
E
E
R
K
S
Site 8
T87
N
P
D
E
L
K
T
T
V
E
E
R
K
S
S
Site 9
S93
T
T
V
E
E
R
K
S
S
E
A
S
P
T
A
Site 10
S94
T
V
E
E
R
K
S
S
E
A
S
P
T
A
Q
Site 11
S97
E
R
K
S
S
E
A
S
P
T
A
Q
R
S
K
Site 12
T99
K
S
S
E
A
S
P
T
A
Q
R
S
K
D
H
Site 13
S103
A
S
P
T
A
Q
R
S
K
D
H
S
K
E
C
Site 14
S107
A
Q
R
S
K
D
H
S
K
E
C
I
N
A
A
Site 15
S117
C
I
N
A
A
P
D
S
P
S
K
Q
L
P
D
Site 16
S119
N
A
A
P
D
S
P
S
K
Q
L
P
D
Q
I
Site 17
S127
K
Q
L
P
D
Q
I
S
F
F
S
G
N
P
S
Site 18
S130
P
D
Q
I
S
F
F
S
G
N
P
S
V
E
I
Site 19
Y145
V
H
G
I
M
H
L
Y
K
T
N
K
M
T
S
Site 20
T147
G
I
M
H
L
Y
K
T
N
K
M
T
S
L
K
Site 21
T173
L
T
V
P
A
A
M
T
S
H
D
L
M
K
F
Site 22
T198
M
K
I
I
R
D
S
T
P
N
Q
Y
M
V
L
Site 23
Y202
R
D
S
T
P
N
Q
Y
M
V
L
I
K
F
R
Site 24
Y218
Q
A
D
A
D
S
F
Y
M
T
C
N
G
R
Q
Site 25
S247
E
R
A
E
V
L
K
S
E
D
G
A
S
L
P
Site 26
S252
L
K
S
E
D
G
A
S
L
P
V
M
D
L
T
Site 27
S274
C
L
E
R
M
D
E
S
V
N
G
I
L
T
T
Site 28
T308
P
V
C
R
Y
C
Q
T
P
E
P
V
E
E
N
Site 29
Y340
G
H
I
G
C
G
R
Y
V
S
R
H
A
Y
K
Site 30
Y346
R
Y
V
S
R
H
A
Y
K
H
F
E
E
T
Q
Site 31
T352
A
Y
K
H
F
E
E
T
Q
H
T
Y
A
M
Q
Site 32
T361
H
T
Y
A
M
Q
L
T
N
H
R
V
W
D
Y
Site 33
Y373
W
D
Y
A
G
D
N
Y
V
H
R
L
V
A
S
Site 34
T382
H
R
L
V
A
S
K
T
D
G
K
I
V
Q
Y
Site 35
Y389
T
D
G
K
I
V
Q
Y
E
C
E
G
D
T
C
Site 36
S409
D
A
L
Q
L
E
Y
S
Y
L
L
T
S
Q
L
Site 37
T413
L
E
Y
S
Y
L
L
T
S
Q
L
E
S
Q
R
Site 38
S414
E
Y
S
Y
L
L
T
S
Q
L
E
S
Q
R
I
Site 39
S418
L
L
T
S
Q
L
E
S
Q
R
I
Y
W
E
N
Site 40
Y422
Q
L
E
S
Q
R
I
Y
W
E
N
K
I
V
R
Site 41
T434
I
V
R
I
E
K
D
T
A
E
E
I
N
N
M
Site 42
S468
D
L
L
K
E
K
Q
S
V
E
R
K
C
T
Q
Site 43
T474
Q
S
V
E
R
K
C
T
Q
L
N
T
K
V
A
Site 44
T478
R
K
C
T
Q
L
N
T
K
V
A
K
L
T
N
Site 45
T484
N
T
K
V
A
K
L
T
N
E
L
K
E
E
Q
Site 46
T518
E
E
R
V
L
K
E
T
C
D
Q
K
D
L
Q
Site 47
Y539
Q
L
R
D
V
M
F
Y
L
E
T
Q
Q
K
I
Site 48
S570
N
I
A
M
A
S
A
S
S
P
A
S
S
G
G
Site 49
S574
A
S
A
S
S
P
A
S
S
G
G
S
G
K
L
Site 50
S575
S
A
S
S
P
A
S
S
G
G
S
G
K
L
P
Site 51
S578
S
P
A
S
S
G
G
S
G
K
L
P
S
R
K
Site 52
S583
G
G
S
G
K
L
P
S
R
K
G
R
S
K
R
Site 53
S588
L
P
S
R
K
G
R
S
K
R
G
K
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation