PhosphoNET

           
Protein Info 
   
Short Name:  HSD11B1L
Full Name:  Hydroxysteroid 11-beta-dehydrogenase 1-like protein
Alias:  11-beta-hsd3; 11-beta-hydroxysteroid dehydrogenase type 3; dhi1l; hsd11b1l; hsd11b1l protein; hydroxysteroid (11-beta) dehydrogenase 1-like; hydroxysteroid 11-beta-dehydrogenase 1-like protein; scdr10; short chain dehydrogenase/reductase 10; short-chain dehydrogenase/reductase 10; short-chain dehydrogenase/reductase 10 isoform a; short-chain dehydrogenase/reductase 10 isoform b; short-chain dehydrogenase/reductase 10 isoform c; short-chain dehydrogenase/reductase 10 isoform d; short-chain dehydrogenase/reductase 10 isoform e; short-chain dehydrogenase/reductase 10 isoform f; short-chain dehydrogenase/reductase 10a; short-chain dehydrogenase/reductase 10b; short-chain dehydrogenase/reductase 10c; short-chain dehydrogenase/reductase 10d; short-chain dehydrogenase/reductase 10e; short-chain dehydrogenase/reductase 10f; short-chain dehydrogenase/reductase 10g
Type:  EC 1.1.1.-; Oxidoreductase
Mass (Da):  34290
Number AA:  315
UniProt ID:  Q7Z5J1
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005576     Uniprot OncoNet
Molecular Function:  GO:0005488  GO:0016491   PhosphoSite+ KinaseNET
Biological Process:  GO:0055114     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y17GALFFAYYWDDNFDP
Site 2S26DDNFDPASLQGARVL
Site 3Y47GVGEELAYHYARLGS
Site 4Y49GEELAYHYARLGSHL
Site 5S54YHYARLGSHLVLTAH
Site 6S90YIAADMASPEAPESV
Site 7S96ASPEAPESVVQFALD
Site 8T123IGGAPAGTRARSPQA
Site 9S127PAGTRARSPQATRWL
Site 10T131RARSPQATRWLMQVN
Site 11S152LTSRALPSLTDSKGS
Site 12T154SRALPSLTDSKGSLV
Site 13S164KGSLVVVSSLLGRVP
Site 14S165GSLVVVSSLLGRVPT
Site 15T172SLLGRVPTSFSTPYS
Site 16S175GRVPTSFSTPYSAAK
Site 17T176RVPTSFSTPYSAAKF
Site 18S179TSFSTPYSAAKFALD
Site 19S217LGLRDRASAAEAVRS
Site 20S224SAAEAVRSSTSRPRQ
Site 21S225AAEAVRSSTSRPRQP
Site 22T226AEAVRSSTSRPRQPE
Site 23S227EAVRSSTSRPRQPEH
Site 24S241HRGVPLQSQTAMFLP
Site 25T243GVPLQSQTAMFLPPT
Site 26T256PTVPGARTLTETPLR
Site 27T258VPGARTLTETPLRGW
Site 28T260GARTLTETPLRGWPQ
Site 29S272WPQPKMKSSRQKSKT
Site 30S273PQPKMKSSRQKSKTE
Site 31S277MKSSRQKSKTEKNDG
Site 32T279SSRQKSKTEKNDGHL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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