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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ANKAR
Full Name:
Ankyrin and armadillo repeat-containing protein
Alias:
ankyrin and armadillo repeat containing; ankyrin and armadillo repeat-containing; FLJ25415
Type:
Mass (Da):
162060
Number AA:
UniProt ID:
Q7Z5J8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T20
E
Q
V
Q
D
E
D
T
Y
L
E
N
L
A
I
Site 2
Y21
Q
V
Q
D
E
D
T
Y
L
E
N
L
A
I
Q
Site 3
S32
L
A
I
Q
R
N
A
S
A
F
F
E
K
Y
D
Site 4
Y38
A
S
A
F
F
E
K
Y
D
R
S
E
I
Q
E
Site 5
S41
F
F
E
K
Y
D
R
S
E
I
Q
E
L
L
T
Site 6
S56
T
A
L
V
S
W
L
S
A
K
E
D
V
R
S
Site 7
S63
S
A
K
E
D
V
R
S
Q
V
D
L
P
C
G
Site 8
Y97
D
P
T
A
L
L
D
Y
R
E
V
H
Q
M
I
Site 9
Y126
S
I
S
L
E
A
N
Y
D
Q
S
S
S
C
Q
Site 10
S129
L
E
A
N
Y
D
Q
S
S
S
C
Q
L
P
P
Site 11
S130
E
A
N
Y
D
Q
S
S
S
C
Q
L
P
P
A
Site 12
S131
A
N
Y
D
Q
S
S
S
C
Q
L
P
P
A
Y
Site 13
Y138
S
C
Q
L
P
P
A
Y
Y
D
T
R
I
G
Q
Site 14
Y139
C
Q
L
P
P
A
Y
Y
D
T
R
I
G
Q
I
Site 15
Y162
K
A
L
W
H
G
I
Y
M
P
K
E
K
R
A
Site 16
S172
K
E
K
R
A
R
F
S
E
L
W
R
A
I
M
Site 17
T189
D
P
D
G
K
P
Q
T
N
K
D
I
F
S
E
Site 18
S195
Q
T
N
K
D
I
F
S
E
F
S
S
A
G
L
Site 19
T203
E
F
S
S
A
G
L
T
D
I
T
K
D
P
D
Site 20
T206
S
A
G
L
T
D
I
T
K
D
P
D
F
N
E
Site 21
Y215
D
P
D
F
N
E
I
Y
D
E
D
V
N
E
D
Site 22
T224
E
D
V
N
E
D
P
T
Y
D
P
N
S
P
E
Site 23
Y225
D
V
N
E
D
P
T
Y
D
P
N
S
P
E
E
Site 24
S229
D
P
T
Y
D
P
N
S
P
E
E
T
A
V
F
Site 25
T248
E
N
I
M
L
K
L
T
F
S
T
T
Q
I
Q
Site 26
Y257
S
T
T
Q
I
Q
Q
Y
E
N
V
F
I
F
E
Site 27
Y279
A
I
K
Y
N
Q
D
Y
L
D
I
C
T
Y
Q
Site 28
Y285
D
Y
L
D
I
C
T
Y
Q
R
L
Q
Q
R
L
Site 29
Y293
Q
R
L
Q
Q
R
L
Y
L
Q
K
K
I
I
Q
Site 30
Y337
K
K
K
M
K
V
P
Y
L
S
S
L
L
Q
P
Site 31
S339
K
M
K
V
P
Y
L
S
S
L
L
Q
P
F
S
Site 32
S340
M
K
V
P
Y
L
S
S
L
L
Q
P
F
S
D
Site 33
S346
S
S
L
L
Q
P
F
S
D
D
K
V
K
T
E
Site 34
T352
F
S
D
D
K
V
K
T
E
R
E
L
P
P
F
Site 35
Y361
R
E
L
P
P
F
I
Y
G
R
D
F
K
C
Q
Site 36
Y377
F
H
Y
K
E
N
Q
Y
F
H
V
H
G
G
I
Site 37
S389
G
G
I
E
F
D
I
S
T
P
S
I
E
N
A
Site 38
S392
E
F
D
I
S
T
P
S
I
E
N
A
L
E
D
Site 39
T414
I
R
D
C
A
A
N
T
F
I
E
D
S
G
Y
Site 40
Y421
T
F
I
E
D
S
G
Y
K
E
Y
Y
S
I
P
Site 41
Y425
D
S
G
Y
K
E
Y
Y
S
I
P
V
M
E
F
Site 42
Y438
E
F
H
G
K
S
Y
Y
V
I
Y
F
E
L
E
Site 43
Y441
G
K
S
Y
Y
V
I
Y
F
E
L
E
T
F
Y
Site 44
T475
R
L
K
R
L
P
L
T
D
A
Q
L
H
E
Q
Site 45
S497
K
R
A
M
K
C
K
S
I
P
F
G
M
K
S
Site 46
S504
S
I
P
F
G
M
K
S
A
V
E
R
G
L
S
Site 47
T516
G
L
S
A
V
F
H
T
F
S
R
K
T
S
S
Site 48
S518
S
A
V
F
H
T
F
S
R
K
T
S
S
S
T
Site 49
T521
F
H
T
F
S
R
K
T
S
S
S
T
I
N
V
Site 50
S522
H
T
F
S
R
K
T
S
S
S
T
I
N
V
S
Site 51
S523
T
F
S
R
K
T
S
S
S
T
I
N
V
S
D
Site 52
S524
F
S
R
K
T
S
S
S
T
I
N
V
S
D
E
Site 53
T525
S
R
K
T
S
S
S
T
I
N
V
S
D
E
A
Site 54
S529
S
S
S
T
I
N
V
S
D
E
A
G
Y
T
I
Site 55
T566
V
N
Q
R
R
F
V
T
F
S
Q
G
P
T
P
Site 56
S568
Q
R
R
F
V
T
F
S
Q
G
P
T
P
L
H
Site 57
Y596
L
L
C
S
K
A
D
Y
T
L
S
E
K
R
G
Site 58
T597
L
C
S
K
A
D
Y
T
L
S
E
K
R
G
W
Site 59
S599
S
K
A
D
Y
T
L
S
E
K
R
G
W
M
P
Site 60
S628
A
L
C
R
K
D
P
S
L
L
E
A
E
A
T
Site 61
T635
S
L
L
E
A
E
A
T
A
E
N
Q
C
T
P
Site 62
T685
L
S
V
L
T
F
H
T
E
V
L
K
Y
I
I
Site 63
Y714
E
M
L
Q
C
E
S
Y
K
R
R
M
M
A
V
Site 64
S767
C
K
T
V
G
L
L
S
N
I
S
T
H
K
S
Site 65
T771
G
L
L
S
N
I
S
T
H
K
S
A
V
H
A
Site 66
S774
S
N
I
S
T
H
K
S
A
V
H
A
L
V
E
Site 67
Y822
N
K
D
V
I
A
K
Y
N
G
I
P
S
L
I
Site 68
Y869
R
E
H
K
G
L
P
Y
L
I
R
F
L
S
S
Site 69
S875
P
Y
L
I
R
F
L
S
S
D
S
D
V
L
K
Site 70
S922
L
F
K
G
K
Q
I
S
V
Q
M
K
G
A
M
Site 71
S949
Q
K
A
F
L
E
K
S
L
T
K
Y
L
L
K
Site 72
Y986
Q
T
L
K
Q
Q
K
Y
M
A
E
Q
I
G
Y
Site 73
S1019
G
E
A
V
I
A
L
S
K
D
S
R
M
H
Q
Site 74
S1074
A
H
T
S
N
P
V
S
Q
Q
F
V
V
D
E
Site 75
S1096
Q
L
L
R
N
H
P
S
P
N
I
K
V
E
V
Site 76
Y1129
H
E
N
E
G
F
E
Y
A
D
V
L
Y
L
L
Site 77
Y1134
F
E
Y
A
D
V
L
Y
L
L
H
S
T
E
K
Site 78
Y1163
F
N
N
R
F
Q
Q
Y
L
I
L
E
S
G
I
Site 79
T1183
F
E
R
F
L
E
S
T
V
E
T
E
K
A
M
Site 80
T1209
I
R
D
M
D
H
I
T
L
S
A
R
G
V
T
Site 81
Y1262
G
T
I
Q
R
L
C
Y
H
L
Y
S
G
I
E
Site 82
Y1265
Q
R
L
C
Y
H
L
Y
S
G
I
E
E
V
R
Site 83
T1283
S
S
A
L
G
Y
L
T
Y
N
A
N
A
F
R
Site 84
S1311
I
R
I
K
N
N
I
S
R
D
A
S
I
N
P
Site 85
S1315
N
N
I
S
R
D
A
S
I
N
P
A
F
L
K
Site 86
T1329
K
E
F
Q
M
Q
Q
T
L
V
G
L
P
S
L
Site 87
S1335
Q
T
L
V
G
L
P
S
L
S
L
E
K
N
G
Site 88
S1369
P
K
I
Q
P
K
D
S
L
T
L
L
P
P
V
Site 89
T1371
I
Q
P
K
D
S
L
T
L
L
P
P
V
T
N
Site 90
S1392
A
T
K
K
T
K
D
S
H
N
I
F
S
F
S
Site 91
S1397
K
D
S
H
N
I
F
S
F
S
S
T
I
T
S
Site 92
S1399
S
H
N
I
F
S
F
S
S
T
I
T
S
D
I
Site 93
S1400
H
N
I
F
S
F
S
S
T
I
T
S
D
I
T
Site 94
T1401
N
I
F
S
F
S
S
T
I
T
S
D
I
T
N
Site 95
S1404
S
F
S
S
T
I
T
S
D
I
T
N
V
S
R
Site 96
T1407
S
T
I
T
S
D
I
T
N
V
S
R
P
R
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation