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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IRF2BP2
Full Name:
Interferon regulatory factor 2-binding protein 2
Alias:
Interferon regulatory factor 2 binding protein 2; Interferon regulatory factor-2 binding protein 2A; IRF-2-binding protein 2; IRF-2BP2
Type:
Mass (Da):
61025
Number AA:
587
UniProt ID:
Q7Z5L9
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
A
A
A
S
R
R
Q
S
C
Y
L
C
D
L
P
Site 2
Y17
A
S
R
R
Q
S
C
Y
L
C
D
L
P
R
M
Site 3
Y43
V
C
R
G
C
V
N
Y
E
G
A
D
R
V
E
Site 4
S71
G
C
F
P
E
G
R
S
P
P
G
A
A
A
S
Site 5
S78
S
P
P
G
A
A
A
S
A
A
A
K
P
P
P
Site 6
S87
A
A
K
P
P
P
L
S
A
K
D
I
L
L
Q
Site 7
Y117
A
P
Q
A
L
E
R
Y
P
L
A
A
A
A
E
Site 8
S131
E
R
P
P
R
L
G
S
D
F
G
S
S
R
P
Site 9
S135
R
L
G
S
D
F
G
S
S
R
P
A
A
S
L
Site 10
S141
G
S
S
R
P
A
A
S
L
A
Q
P
P
T
P
Site 11
T147
A
S
L
A
Q
P
P
T
P
Q
P
P
P
V
N
Site 12
S175
P
P
E
L
N
R
Q
S
P
K
P
R
R
G
H
Site 13
T197
P
L
M
N
G
S
A
T
P
L
P
T
A
L
G
Site 14
T219
S
L
A
A
V
S
G
T
A
A
A
S
L
G
S
Site 15
T230
S
L
G
S
A
Q
P
T
D
L
G
A
H
K
R
Site 16
S240
G
A
H
K
R
P
A
S
V
S
S
S
A
T
V
Site 17
S242
H
K
R
P
A
S
V
S
S
S
A
T
V
E
H
Site 18
S243
K
R
P
A
S
V
S
S
S
A
T
V
E
H
E
Site 19
S244
R
P
A
S
V
S
S
S
A
T
V
E
H
E
Q
Site 20
S272
A
H
R
G
P
A
D
S
L
S
T
A
A
G
A
Site 21
S274
R
G
P
A
D
S
L
S
T
A
A
G
A
A
E
Site 22
S283
A
A
G
A
A
E
L
S
A
E
G
A
G
K
S
Site 23
S290
S
A
E
G
A
G
K
S
R
G
S
G
E
Q
D
Site 24
S293
G
A
G
K
S
R
G
S
G
E
Q
D
W
V
N
Site 25
T304
D
W
V
N
R
P
K
T
V
R
D
T
L
L
A
Site 26
T308
R
P
K
T
V
R
D
T
L
L
A
L
H
Q
H
Site 27
S318
A
L
H
Q
H
G
H
S
G
P
F
E
S
K
F
Site 28
S323
G
H
S
G
P
F
E
S
K
F
K
K
E
P
A
Site 29
S360
T
A
R
K
R
K
P
S
P
E
P
E
G
E
V
Site 30
S381
G
E
A
Q
P
W
L
S
T
S
T
E
G
L
K
Site 31
T392
E
G
L
K
I
P
M
T
P
T
S
S
F
V
S
Site 32
T394
L
K
I
P
M
T
P
T
S
S
F
V
S
P
P
Site 33
S395
K
I
P
M
T
P
T
S
S
F
V
S
P
P
P
Site 34
S396
I
P
M
T
P
T
S
S
F
V
S
P
P
P
P
Site 35
S399
T
P
T
S
S
F
V
S
P
P
P
P
T
A
S
Site 36
T404
F
V
S
P
P
P
P
T
A
S
P
H
S
N
R
Site 37
S406
S
P
P
P
P
T
A
S
P
H
S
N
R
T
T
Site 38
S409
P
P
T
A
S
P
H
S
N
R
T
T
P
P
E
Site 39
T413
S
P
H
S
N
R
T
T
P
P
E
A
A
Q
N
Site 40
S449
K
D
A
N
Q
V
H
S
T
T
R
R
N
S
N
Site 41
T450
D
A
N
Q
V
H
S
T
T
R
R
N
S
N
S
Site 42
T451
A
N
Q
V
H
S
T
T
R
R
N
S
N
S
P
Site 43
S455
H
S
T
T
R
R
N
S
N
S
P
P
S
P
S
Site 44
S457
T
T
R
R
N
S
N
S
P
P
S
P
S
S
M
Site 45
S460
R
N
S
N
S
P
P
S
P
S
S
M
N
Q
R
Site 46
S462
S
N
S
P
P
S
P
S
S
M
N
Q
R
R
L
Site 47
S463
N
S
P
P
S
P
S
S
M
N
Q
R
R
L
G
Site 48
S492
L
E
P
V
H
P
A
S
L
P
D
S
S
L
A
Site 49
S496
H
P
A
S
L
P
D
S
S
L
A
T
S
A
P
Site 50
S537
C
F
P
C
S
R
Q
S
I
K
Q
Q
G
A
S
Site 51
S544
S
I
K
Q
Q
G
A
S
G
E
V
Y
C
P
S
Site 52
Y548
Q
G
A
S
G
E
V
Y
C
P
S
G
E
K
C
Site 53
S551
S
G
E
V
Y
C
P
S
G
E
K
C
P
L
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation